Navigation Links
Researchers find that eating high levels of fructose impairs memory in rats
Date:7/16/2009

ATLANTA Researchers at Georgia State University have found that diets high in fructose a type of sugar found in most processed foods and beverages impaired the spatial memory of adult rats.

Amy Ross, a graduate student in the lab of Marise Parent, associate professor at Georgia State's Neuroscience Institute and Department of Psychology, fed a group of Sprague-Dawley rats a diet where fructose represented 60 percent of calories ingested during the day.

She placed the rats in a pool of water to test their ability to learn to find a submerged platform, which allowed them to get out of the water. She then returned them to the pool two days later with no platform present to see if the rats could remember to swim to the platform's location.

"What we discovered is that the fructose diet doesn't affect their ability to learn," Parent said. "But they can't seem to remember as well where the platform was when you take it away. They swam more randomly than rats fed a control diet."

Fructose, unlike another sugar, glucose, is processed almost solely by the liver, and produces an excessive amount of triglycerides fat which get into the bloodstream. Triglycerides can interfere with insulin signaling in the brain, which plays a major role in brain cell survival and plasticity, or the ability for the brain to change based on new experiences.

Results were similar in adolescent rats, but it is unclear whether the effects of high fructose consumption are permanent, she said.

Parent's lab works with Timothy Bartness, Regents' Professor of Biology, and John Mielke of the University of Waterloo in Waterloo, Ontario, Canada to examine how diet influences brain function.

Although humans do not eat fructose in levels as high as rats in the experiments, the consumption of foods sweetened with fructose which includes both common table sugar, fruit juice concentrates, as well as the much-maligned high fructose corn syrup has been increasing steadily. High intake of fructose is associated with numerous health problems, including insulin insensitivity, type II diabetes, obesity and cardiovascular disease.

"The bottom line is that we were meant to have an apple a day as our source of fructose," Parent said. "And now, we have fructose in almost everything." Moderation is key, as well as exercise, she said.

Exercise is a next step in ongoing research, and Parent's team will investigate whether exercise might mitigate the memory effects of high fructose intake. Her lab is also researching whether the intake of fish oil can prevent the increase of triglycerides and memory deficits. Results from that research will be presented by her graduate student Emily Bruggeman at the 2009 Society for Neuroscience meeting in Chicago this fall.


'/>"/>

Contact: Jeremy Craig
jcraig@gsu.edu
404-413-1357
Georgia State University
Source:Eurekalert

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2017)... ... August 23, 2017 , ... Loyale Healthcare ... Growth. Mr. Smith joins other recent high-profile hires including Frank Massi, Chief Revenue ... began in 1993, helping physician practices and hospitals automate their clinical and financial ...
(Date:8/23/2017)... ... 23, 2017 , ... CEFEX, the Centre for Fiduciary Excellence, ... representing best practices in the retirement plan industry. The independent CEFEX Investment Advisor ... verify that NFP’s retirement division focuses on putting clients’ interests first and acting ...
(Date:8/23/2017)... ... August 23, 2017 , ... Cirrus Medical Staffing, ... new website, http://www.cirrusmedicalstaffing.com . The new site pairs a robust job search ... professionals who are traveling on short-term assignments to healthcare facilities around the country. ...
(Date:8/23/2017)... CA (PRWEB) , ... August 23, 2017 , ... Silicon ... to announce a new blog archive organized month-by-month. The new rotation of archived blog ... Local Bay Area residents searching information about hair transplantation can review details online and ...
(Date:8/23/2017)... ... 2017 , ... The non-profit Seafood Nutrition Partnership (SNP) ... the Science Symposium in partnership with the Global Organization for EPA and DHA ... a forum for global leaders in human nutrition to outline the latest consensus ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... and Gulf Coast Regional Blood Center to host a blood ... Law family has had 3 members that needed blood products ... is partnering with Gulf Coast Regional Blood Center of ... supplies are running low. Gulf Coast Regional Blood Center,s inventory is ... is why the blood center reached out to Mostyn Law ...
(Date:8/15/2017)...  AOTI Inc. announced today that its fully owned ... a New York City Office in Yonkers, New York ... Wound Oxygen (TWO 2 ) homecare therapy. This new East Coast ... Care (ACHC) under the company,s DMEPOS accreditation for Home/Durable Medical Equipment ... Advanced Oxygen Therapy ...
(Date:8/8/2017)... TEL AVIV, Israel, Aug. 8, 2017  BioLineRx Ltd. ... and immunology, today reports its financial results for the ... and achievements during the second quarter 2017 and to ... on multiple clinical development programs for the Company,s lead ... Phase 3 pivotal study with BL-8040 as novel stem ...
Breaking Medicine Technology: