Navigation Links
Researchers find smoking may increase risk for lung disease
Date:3/9/2011

Boston, MA A team of researchers at Brigham and Womens Hospital (BWH) have found that approximately one out of every twelve adult smokers have abnormal lung densities present on chest computed tomography (CT) images suggestive of interstitial lung disease which is associated with substantial reductions in lung volumes. In addition, despite being positively associated with smoking, these lung densities were inversely not associated with emphysema. This research is published online on March 10th in the New England Journal of Medicine.

It is increasingly acknowledged that interstitial lung disease may evolve prior to the development of symptoms. Although it is known that smoking can cause some forms of interstitial lung disease, the prevalence of these chest CT scan abnormalities and their effect on lung volumes had been unclear. This manuscript highlights the degree of lung volume reduction associated to previously unrecognized interstitial lung abnormalities in smokers, said Hiroto Hatabu, MD, and Ivan Rosas, MD of the Divisions of Radiology and Pulmonary/Critical Care Medicine at BWH.

In this study, researchers characterized the presence of interstitial lung abnormalities in 2416 participants from the COPDGene study. The researchers found that interstitial lung abnormalities are associated with both reduced total lung capacity and less emphysema in smokers. The team also found that smokers with interstitial lung abnormalities are at an increased risk for a restrictive reduced lung oxygen volume.lung deficit.

The fact that smoking can result in distinct, and to some degree, physiologically divergent pulmonary conditions highlights the need for a better understanding of the phenotypic, environmental, and genetic backgrounds that can predispose smokers to diverse pulmonary diseases, said George Washko, MD, and Gary Hunninghake, MD, of the Division of Pulmonary/Critical Care Medicine at BWH.

Further research is needed to definitely characterize the link between interstitial lung abnormalities present on chest CT and idiopathic pulmonary fibrosis, the most common and severe form of interstitial lung disease.


'/>"/>

Contact: Holly Brown-Ayers
hbrown-ayers@partners.org
617-534-1603
Brigham and Women's Hospital
Source:Eurekalert

Related medicine news :

1. Researchers identify new biomarker for Creutzfeldt-Jakob disease, the human form of mad cow disease
2. Researchers selectively control anxiety pathways in the brain
3. Researchers develop synthetic compound that may lead to drugs to fight pancreatic, lung cancer
4. Report: International collaboration between researchers results in greater recognition
5. U of M researchers using salmonella to fight cancer
6. University of South Florida researchers find blood-brain barrier damaged by disease
7. Boston researchers create SMArt platform architecture, launch $5,000 health app competition
8. UCLA researchers use nano-Velcro technology to improve capture of circulating cancer cells
9. Aging in place preserves seniors independence, reduces care costs, MU researchers find
10. Elderly see pedestrians half as often as younger drivers, according to Ben-Gurion U. researchers
11. Researchers use human cues to improve computer user-friendliness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... ... February 24, 2017 , ... With millions of Americans and ... that we all are aware of our options and are empowered with strength ... the launch of its newest edition of "Vision and Hearing" in USA Today, ...
(Date:2/24/2017)... Texas (PRWEB) , ... February 24, 2017 , ... Yisrayl ... that focuses on Bible Prophecy concerning this present generation. Yisrayl makes an astounding ... this current generation. He explains that the Bible details the current times so ...
(Date:2/24/2017)... Emeryville, CA (PRWEB) , ... February 24, 2017 ... ... Esparza for qualifying into the Senior International Elite division on February 12th. ... All Around divisions at the elite qualifier competition held in Las Vegas, Nevada. ...
(Date:2/23/2017)... ... February 23, 2017 , ... ... exclusively to funding innovative lymphoma research and serving the lymphoma community through a ... to the La Gorce Country Club in Miami Beach to host its Swirl: ...
(Date:2/23/2017)... ... 23, 2017 , ... Rosica Communications, a national PR ... media management, corporate communications, SEO and cause marketing, is opening an office in ... Hampshire, Massachusetts and Canada, Rosica will focus on expanding its footprint. , ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Feb. 24, 2017 Juan ... & Associates PC , a boutique securities firm headquartered ... York City , announces that a class action ... Massachusetts  against Inotek Pharmaceuticals Corporation (NASDAQ: ... the Company,s securities between July 23, 2015 and December 30, ...
(Date:2/24/2017)... , Feb. 23, 2017  Directors from Pharma To Market Pty ... have joined forces, resulting in the founding of Pharma To Market ... Pharma To Market are pleased to announce their expansion into ... Singapore . The company are delighted to appoint ... of the Singapore based entity. Joelle brings ...
(Date:2/24/2017)... , Feb. 24, 2017  Xynomic Pharmaceuticals, Inc., ... announced that it has acquired exclusive worldwide rights ... best-in-class innovative HDAC inhibitor targeting hematological and solid ... 14 Phase 1 and 2 clinical trials of ... have already been completed, demonstrating that ...
Breaking Medicine Technology: