Navigation Links
Researchers find predictive tests and early treatment delay progression of blood cell cancer
Date:11/6/2008

ROCHESTER, Minn. - Mayo Clinic researchers say they have moved closer to their goal of providing personalized care for a common blood cell cancer. They have found that the use of predictive biomarkers along with two targeted treatments significantly delays the need for conventional chemotherapy in patients with early-stage, but high-risk, chronic lymphoid leukemia (CLL).

Their study, published Oct. 15 in the journal Cancer, found that in a small group of patients the use of the new tools delayed the need for standard chemotherapy treatment to about four years after cancer diagnosis. Typically, people with this kind of high-risk CLL require chemotherapy at about two years after diagnosis.

Because this was a small phase II study, the researchers cannot yet say that this strategy will improve the quality or duration of life for patients. However, they say that because of these promising findings, all CLL patients at Mayo Clinic now undergo the predictive tests, whose results can be used to risk-stratify therapy, including enrollment in ongoing experimental treatments if appropriate.

The two targeted therapies studied, alemtuzumab and rituximab, are widely used in advanced-stage CLL. Both are monoclonal antibodies that produce an immune response against the cancer cells.

"This is the first publication of a study on CLL in which patients were selected for early treatment of their disease based on molecular prognostic markers, and it is also the first one to test a combination of targeted therapies in a group of patients who would not ordinarily be treated yet," says the study's lead investigator, Mayo hematologist Clive Zent, M.D.

"The standard of care for these patients is to watch and wait until patients develop more advanced disease and then to treat them with chemotherapy and monoclonal antibodies," he says. "We believe this new approach is better for patients because it identifies those who will develop aggre
'/>"/>

Contact: Karl Oestreich
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Researchers describe how chronic inflammation can lead to stomach cancer
2. Researchers ID Genetic Markers for Esophageal Cancer
3. Researchers identify mechanism, possible drug treatment for tumors in neurofibromatosis
4. Cancer requires support from immune system to develop, UT Southwestern researchers report
5. Researchers find new chemical key that could unlock hundreds of new antibiotics
6. Penn researchers find key to Sonic hedgehog control of brain development
7. Temple researchers look for behavioral link between breastfeeding and lower risk of obesity
8. MU researchers advance health communication for at-risk populations
9. Researchers Find More Genes Linked to Lung Cancer
10. Researchers estimate lives lost due to delay in antiretroviral drug use for HIV/AIDS in South Africa
11. Georgetown University Med Center reproductive health researchers tackle public health concerns
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... The exciting information sessions and AMTC auditions ... Lewis and Bob Wiley. The team of scouts ... the desire to illuminate entertainment with the light of ... invited to join the Bridge Training Program ... Sept. 6, Charlotte Convention Center, 501 South College St., ...
(Date:9/2/2014)... September 02, 2014 Friendship Village ... logo. “This creates a contemporary marketing presence ... and its parent organization, Friendship Senior Options,” said ... Senior Options. “By changing the logo, we are ... communicated to seniors and their families.” , Friendship ...
(Date:9/2/2014)... New York, NY (PRWEB) September 02, 2014 ... and other new blood thinners is growing at a ... ) continue to mount in courts around the U.S., ... published in American Journal of Medicine, within a year ... to be prescribed Xarelto as warfarin, a blood thinner ...
(Date:9/2/2014)... Los Angeles, CA (PRWEB) September 02, 2014 ... an article on its website titled “Why You Should ... more than 80 percent of the global population breathes ... droplets and particles of pollution lodge in the skin’s ... the body’s natural barrier to free radicals that may ...
(Date:9/2/2014)... with lumpectomy followed by radiation therapy survived as ... to a large study conducted by researchers at ... Cancer Prevention Institute of California. , The comprehensive ... disease is the first to directly compare survival ... bilateral mastectomy (the removal of both breasts), unilateral ...
Breaking Medicine News(10 mins):Health News:Actors, Models and Talent for Christ Auditions Are Set for Charlotte and Omaha on Saturday, September 6, 2014 2Health News:Friendship Village of Schaumburg In Illinois Announces New Logo 2Health News:Xarelto Lawsuit News: Bernstein Liebhard LLP Comments on Growing Use of Xarelto in Spite of Mounting Product Liability Litigation 2Health News:Xarelto Lawsuit News: Bernstein Liebhard LLP Comments on Growing Use of Xarelto in Spite of Mounting Product Liability Litigation 3Health News:Xarelto Lawsuit News: Bernstein Liebhard LLP Comments on Growing Use of Xarelto in Spite of Mounting Product Liability Litigation 4Health News:Simon Ourian, Kim Kardashian’s Doctor: Air Pollution May Be Aging Your Skin 2Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 2Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 3Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 4
... for Immunization (IFFIm) will be providing life saving vaccines ... the project costing $4 billion to be funded by ... said the scheme, the International Finance Facility for Immunization ... children over the next 10 years and another five ...
... Terming the disease as "virus enemy number one", the Indian ... recruits in all the three wings from Oct 1. ... number one// and, therefore, AIDS/HIV testing for all new recruits ... made mandatory from Oct 1," said the Director General of ...
... a nationwide study in USA to see if the ... hospitals. ,The study will enroll of more ... angioplasty //can be safely performed in smaller, community hospitals, ... to enroll the first study patients in early fall ...
... to launch her diet plan, which recommends eating of bread to reduce ... The Bread for Life Diet: The High-on-Carbs Weight Loss Plan.// ... slices a day for women and 16 slices a day for men ... program. ,The bread is not a gimmick. Rather it is ...
... meant embracing death together for a married couple in West ... dying a little of humiliation everyday. ,In an act driven// ... his 25-year-old wife and then hanged himself in the Durgapur ... , ,Probir and Basanti Sarkar were a happy couple ...
... to lose weight for health, it is equally important to ... unlimited servings of fruits, vegetables, whole grains and other such ... to adapt and follow and is more effective than the ... into it! ,A low-fat, plant-based diet has been found ...
Cached Medicine News:Health News:European Countries To Fund $4 Billion For Vaccination For Poor Children’ 2Health News:Testing For HIV/AIDS Compulsory For New Military Recruits 2Health News:Weight loss accomplished by high carbohydrate, vegan diet 2
(Date:9/2/2014)... Spanien, September 2, 2014 ... dem ESC-Kongress 2014 präsentierte GARFIELD-AF-Register bietet ... Behandlungsergebnisse von schlaganfallgefährdeten Patienten in der ... Die Daten der nahezu ... innovativen und unabhängigen Forschungsinitiative zur Untersuchung ...
(Date:9/2/2014)... September 2, 2014 , ... 2014 provide insight into treatment and outcomes of ... practice --   Data from nearly ... in the FIELD-Atrial Fibrillation (GARFIELD-AF), an innovative, independent ... strategies for atrial fibrillation (AF) patients remain sub-optimal ...
(Date:9/2/2014)... Sept. 2, 2014 Particle Sciences, the leading ... investment in development and manufacturing capabilities with the addition ... Mueller , Particle Sciences, Associate Director Clinical Production, "The ... clean room square footage, equipment and staff across the ... company now has over 6000ft 2 of operating ...
Breaking Medicine Technology:Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 2Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 3Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 4Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 5Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 6Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 7Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 8Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 9Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 10Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 11Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 2Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 3Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 4Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 5Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 6Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 7Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 8Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 9Particle Sciences Expands Drug Eluting Device Capabilities and Overall Clinical Trial Manufacturing Resources 2
... 2012 Medical Alarm Concepts Holding, Inc. (OTCQB: MDHI.PK), ... system that allows the user to speak and listen ... for this week,s media test.   The ... Inspirational TV, Fox News Channel, and MSNBC. The spot ...
... today releases further intriguing insights uncovered by its ,Face ... five surveyed European women think that it,s ,the norm, to ... and laser treatments to maintain their looks as they grow ... Hollywood elite, two thirds of the respondents admit that they ...
Cached Medicine Technology:Medical Alarm Concepts and Harrington Media Announce Final Schedule for MediPendant™ Nationwide Television Test Launch 2The Changing Face of Beauty 2The Changing Face of Beauty 3The Changing Face of Beauty 4The Changing Face of Beauty 5
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: