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Researchers find possible clues to tamoxifen resistance in breast cancer patients
Date:3/30/2011

studies have found the proteins to be associated in various ways with breast cancer. But not all these previous findings are consistent with the findings of this study. "Thus, the status of Rho GDI-alpha as a marker of tamoxifen resistance is unclear," they write.

The editorialists also comment on the increasing number of genetic alterations emerging in breast cancer. "In the next several years," they write, "many entire breast cancer genomes will be published, revealing for the first time the enormous scale of the disruption of the human genome associated with the development of this disease." After that, they say, efforts to understand the functions of disrupted genes "will be essential for the next surge of progress."


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Contact: Caroline McNeil
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2

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