Navigation Links
Researchers find important 'target' playing role in tobacco-related lung cancers
Date:2/9/2012

on-small cell lung cancer in patients with a history of tobacco use, and particularly by tobacco's nicotine component. The researchers stated that upon exposure to nicotine, cells express high levels of IKBKE protein. In their study co-expression of STAT3 and IKBKE was "observed in primary non-small cell lung cancer."

"Current treatments for non-small cell lung cancer include surgery, radiotherapy and chemotherapy," explained Cheng. "Advanced patients generally develop chemotherapy and radiotherapy resistance, so there is a great need to understand the molecular mechanism of therapy resistance in order to find 'targets' to overcome resistance."

The discovery that STAT3 appears to regulate IKBKE in response to nicotine induced by tobacco carcinogen may also help develop a strategy for an intervention in non-small cell lung cancer by targeting IKBKE.


'/>"/>

Contact: Ferdie De Vega
Ferdinand.DeVega@moffitt.org
813-745-7858
H. Lee Moffitt Cancer Center & Research Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... from our parents shapes many aspects of our lives. ... epigenome that is set during development, but can be ... by those of our parents and grandparents. , The ... supporting proteins that determine whether genes are expressed or ... our own health, but also that it may be ...
(Date:8/27/2014)... Hudson County, NJ (PRWEB) August 27, 2014 ... that a leading pediatric practice, Hoboken Pediatrics has ... system welcomes Dr. Andrzej Klos, Dr. Piotr Oko, ... the community. Hundreds of highly skilled and experienced ... network of top doctors and practices in Hudson ...
(Date:8/27/2014)... and Germantown, Md., and Denver (PRWEB) August 27, 2014 ... real estate developer , has broken ground on a ... new Holy Cross Health hospital campus in Germantown, an ... Md. Germantown is the third most populous place in ... building on the Holy Cross Germantown Hospital campus is ...
(Date:8/27/2014)... 27, 2014. Kessler Foundation scientists examined the implications ... injury research and rehabilitation. The article by Anthony ... cultural diversity in acquired brain injury (ABI) rehabilitation ... Drs. Lequerica and Krch are research scientists ... Foundation and co-investigators for the Northern New Jersey ...
(Date:8/27/2014)... you experienced worrisome medical symptoms, did you look ... If so, you,re not alone. Consumers are increasingly ... groups to gather anecdotal information and advice, which ... sources. New research to be presented at the ... characteristics of consumers who use the Internet to ...
Breaking Medicine News(10 mins):Health News:Scientists map the 'editing marks' on fly, worm, human genomes 2Health News:Scientists map the 'editing marks' on fly, worm, human genomes 3Health News:Scientists map the 'editing marks' on fly, worm, human genomes 4Health News:Hoboken Pediatrics Joins CarePoint Health Medical Group 2Health News:Hoboken Pediatrics Joins CarePoint Health Medical Group 3Health News:NexCore Breaks Ground on Medical Office Building on Holy Cross Health Campus in Germantown, Maryland 2Health News:NexCore Breaks Ground on Medical Office Building on Holy Cross Health Campus in Germantown, Maryland 3Health News:NexCore Breaks Ground on Medical Office Building on Holy Cross Health Campus in Germantown, Maryland 4Health News:Educated consumers more likely to use potentially unreliable online healthcare information 2
... than 125 leaders,from throughout the state, led by ... multi-year, statewide campaign to Make Delaware,s Kids the,Healthiest ... Health and,Prevention Services (NHPS), encourages and celebrates the ... centers,parents, and other leaders to improve the motivation, ...
... Pa., Oct. 4 The following is an,op-ed by ... Coalition:, As if it isn,t bad enough to ... twice -- imagine being diagnosed with an aggressive form ... medical treatment., That,s precisely what happened to Gina, ...
... Science, Technology and Research,s (A*STAR) Institute of Molecular ... mechanisms that provide a more detailed understanding of ... as Candida albicans transforms into a serious and ... can cause serious and potentially life-threatening infections in ...
... Oct. 9 gift to resource center is just part of what is ... needed at local nonprofit for teens., ... a new home to an estimated $75,000 in furniture,arcade games and supplies. ... McGinnis Mansion in Beaverton, will be donated to the,Sexual Minority Youth Resource ...
... (NYSE: MYL ),today announced that it and its ... settle pending litigation with UCB Societe,Anonyme and UCB Pharma ... 750mg, the generic version of UCB,s Keppra(R). Litigation ... U.S. District,Court for the Northern District of Georgia since ...
... Konashen District, Guyana (Oct. 2, 2007) Three years ... the northern Amazon, the Wai Wai people of Guyana ... the nations first Community Owned Conservation Area. , Under ... community formally designated their land a protected area and ...
Cached Medicine News:Health News:Governor Ruth Ann Minner, U.S. Senator Tom Carper, U.S. Representative Mike Castle and Lt. Governor John Carney Join 125 Delaware Community Leaders Endorsing the Campaign to Make Delaware's Kids the Healthiest in the Nation 2Health News:Governor Ruth Ann Minner, U.S. Senator Tom Carper, U.S. Representative Mike Castle and Lt. Governor John Carney Join 125 Delaware Community Leaders Endorsing the Campaign to Make Delaware's Kids the Healthiest in the Nation 3Health News:Op-Ed: Free Treatment for Breast Cancer Patients Who Are Uninsured 2Health News:Op-Ed: Free Treatment for Breast Cancer Patients Who Are Uninsured 3Health News:How Candida albicans transforms from its normally benign form into life-threatening form 2Health News:Contents of the McGinnis Mansion Refurbishes Portland, Oregon Sexual Minority Youth Center 2Health News:Contents of the McGinnis Mansion Refurbishes Portland, Oregon Sexual Minority Youth Center 3Health News:Mylan Settles Its First-to-File Opportunity on Levetiracetam with UCB 2Health News:Wai Wai choose conservation economy for traditional Amazon territory 2Health News:Wai Wai choose conservation economy for traditional Amazon territory 3
(Date:8/27/2014)... , Aug. 27, 2014 By now, if you ... not living on this planet. The awareness campaign has brought ... has helped to raise over $88.5 Million (and counting) for ... and some companies are starting to as well. ... Orlando, Florida , who actually works with ALS sufferers ...
(Date:8/27/2014)... CHICAGO , Aug. 27, 2014  Hill-Rom Holdings, ... listen to a management presentation at the Morgan Stanley ... p.m. EDT. You are invited to listen ... http://ir.hill-rom.com/events.cfm or access it directly at ... be available one hour after conclusion of the live ...
(Date:8/27/2014)... North American lighting leader OSRAM SYLVANIA ... the new OSRAM ITOS ® PHASER ® 3000, ... microscopy, endoscopy and surgical head lamps that delivers the same ... lamp life. "We,re honored to be recognized by ... new technologies of the past year," said Andreas Osten ...
Breaking Medicine Technology:Acorn Stairlifts Gives a Lift to the ALS Ice Bucket Challenge 2OSRAM ITOS PHASER 3000 Laser and LED Light Module Recognized With Prestigious R&D 100 Award 2OSRAM ITOS PHASER 3000 Laser and LED Light Module Recognized With Prestigious R&D 100 Award 3
Patent Pending lateral flow assay platform that contributes to increased sensitivty...
Iso-Electric Determination Kit; contains 1 bottle of 40 nm Naked Gold Iso-Electric Determination Kit to optimize gold conjugation of antibodies...
Gold Labeling kit for antibodies, the Coat-Block-Run Conjugation Kit pH 5-8; contains 1 bottle each of 20 nm and 40 nm Naked Gold...
Colloidal Gold Conjugated, Goat anti-rabbit IgG (H&L) - 50 OD...
Medicine Products: