Navigation Links
Researchers find gene location that gives rise to neuroblastoma, an aggressive childhood cancer
Date:5/7/2008

initial changes on chromosome 6 in all their body cells eventually led to the genetic abnormalities seen in tumor cells in high-risk forms of the disease.

Because their finding reveals only the first step in a series of molecular events, added Maris, it would be premature to do prenatal genetic testing for the SNPs on chromosome 6. His research team will continue to perform genetic analyses, in search of other gene changes that interact with those SNPs. One data source will be 5,000 tissue samples in Mariss labthe worlds largest collection of neuroblastoma samples, drawing on decades of research into the disease by Maris, his colleagues and predecessors at Childrens Hospital.

This discovery lays the foundation for learning how these initial changes influence biological pathways that lead to neuroblastoma, added Maris. Understanding those pathways may guide us to new and better therapies that precisely target this cancer. Hakonarson added, This study represents one of many ongoing projects to which scientists at The Childrens Hospital of Philadelphia are committed, and we anticipate several comparable discoveries will be made in other common and equally complex pediatric disorders, such as autism, asthma, ADHD and diabetes.


'/>"/>

Contact: Rachel Salis-Silverman
Salis@email.chop.edu
267-426-6063
Children's Hospital of Philadelphia
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... the clinical indicators most strongly associated with concussion is ... evidence-based guidelines for concussion diagnosis, prognosis, and treatment, according ... , official journal of the Congress ... Lippincott Williams & Wilkins , a part of ... on analysis of the best available research data, a ...
(Date:7/10/2014)... the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan ... patients a new therapeutic combination to combat resistant sarcomas. ... treatment could stabilize the growth of these tumors have ... of Cancer ., Sarcomas , Sarcomas are a ... several subtypes. It can affect from children to older ...
(Date:7/9/2014)... If you think winning is one of the key determinants ... along with other mental bonuses ranked near the bottom of ... of 11 big fun factors, according to a new study. ... it comes to the "fun" factor, very little research had ... this elusive conceptuntil now. , The results of this study ...
(Date:7/9/2014)... associated with a small increased risk of prostate cancer, ... cancer according to a new study from Harvard School ... association remained even among men who received regular PSA ... be explained by diagnostic bias. It is the largest ... the link between vasectomy and prostate cancer. , The ...
(Date:7/9/2014)... heretofore hidden ways that cells are regulated, scientists at ... cancer cells more likely to metastasize. , What,s more, ... by blocking two other proteins that are normally linked ... processes could have unexpected ties. , The study, ... Nature , points to the possibility of new cancer ...
Breaking Medicine News(10 mins):Health News:What's a concussion? Review identifies four evidence-based indicators 2Health News:What's a concussion? Review identifies four evidence-based indicators 3Health News:New therapeutic combination to slow resistant sarcomas 2Health News:Being a good sport ranks as the top 'fun' factor in study of youth sports 2Health News:Being a good sport ranks as the top 'fun' factor in study of youth sports 3Health News:Vasectomy may increase risk of aggressive prostate cancer 2Health News:Protein pushes breast cancer cells to metastasize 2Health News:Protein pushes breast cancer cells to metastasize 3
... of his work,to ensure that all Pennsylvanians have access ... said 35,000 uninsured,individuals who have been waiting to enroll ... to receive health coverage at a,monthly premium of $33.50., ... and peace of mind,that every Pennsylvanian deserves," said Governor ...
... 40% of patients stopped taking drugs in Italian study , , ... taking cholesterol-lowering statins doubled their risk of dying in the ... an Italian study finds. , A number of other studies ... the study authors noted. , For instance, the Italian study ...
... cord dysfunction (VCD) is the sudden, abnormal narrowing of the ... is characterized by a noise that can mimic the sound ... an asthma attack though it does not respond to asthma ... the disorder using breathing and relaxation techniques to help the ...
... than visually inspecting the disease, doctors have no genetic blueprint ... Tumors generally are ranked by how deeply the growth has ... the skin, the more lethal the cancer, but some patients ... from thin ones. Two melanoma patients with cancers of ...
... Disease Control report that nearly 25 million women are infected with ... more than three million are thought to have one of the ... warts. , HPV is linked to oropharyngeal cancer and may be ... developed to treat HPV might decrease the risk of these cancers, ...
... group suggests , THURSDAY, Aug. 30 (HealthDay News) -- ... suffer oral allergy syndrome (OAS), which results from a ... and trees and similar proteins in some fresh fruits ... known as pollen-food syndrome -- include: itchiness, tingling or ...
Cached Medicine News:Health News:Governor Rendell Offers adultBasic Coverage to 35,000 Uninsured Pennsylvanians 2Health News:Stopping Statins After Stroke Doubles Death Risk 2Health News:Stopping Statins After Stroke Doubles Death Risk 3Health News:Study finds some kids are being misdiagnosed with asthma 2Health News:Gene signature spells poor outcome 2Health News:Human Papilloma Virus vaccines may decrease chances of oral cancer 2Health News:Pollen, Fruits, Veggies Help Trigger Oral Allergy Syndrome 2
(Date:1/15/2014)... Inc. (Nasdaq: ECTE ) ("Echo"), a medical ... non-invasive, wireless continuous glucose monitoring system, today announced that ... CEO of Echo Therapeutics, will present at "TEN", Noble ... Mr. Doman will make a corporate presentation to ...
(Date:1/15/2014)... , Jan. 15, 2014 Reportlinker.com ... is available in its catalogue: ... – Worldwide Analysis http://www.reportlinker.com/p01957812/Insulin-Pump-Market--Forecast-–-Worldwide-Analysis.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Equipment_and_Supply ... Analysis Insulin Pumps ...
(Date:1/15/2014)... NEW YORK , Jan. 15, 2014 ... research report is available in its catalogue: ... Technologies for Advanced Drug Delivery Systems -- ... http://www.reportlinker.com/p01940411/Global-Markets-and-Technologies-for-Advanced-Drug-Delivery-Systems----Focus-on-End-Users.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology STUDY OBJECTIVES ...
Breaking Medicine Technology:Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 16Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 18
... March 3, 2011 Palatin Technologies, Inc. (NYSE Amex: ... Drug Administration (FDA) has cleared Palatin,s request to begin a ... (IND) application using a subcutaneously administered formulation of PL-3994, an ... of asthma. "We are excited about the ...
... 3, 2011 Cell Therapeutics, Inc. ("CTI") (Nasdaq and MTA: ... the FDA,s Office of New Drugs ("OND") in Maryland and ... contained in its New Drug Application ("NDA") 22-481 support the ... "We appreciate OND,s consideration of our appeal.  While we ...
Cached Medicine Technology:FDA Clears Palatin Technologies' IND Filing to Commence Clinical Studies for Asthma 2FDA's Office of New Drugs Meets With Cell Therapeutics on its Appeal on Pixantrone 2FDA's Office of New Drugs Meets With Cell Therapeutics on its Appeal on Pixantrone 3
... The Thumper Board provides optimum head hyperextension, open ... intubation easier. Placed at strategic locations throughout ... CPR to be started immediately, and easy conversion ... patient application can be done in less than ...
The CryoSurgery console is the control center for CryoCath's surgical probe. It is a modular system made up of a console control unit and a tank dolly system. The system can be used as a unit or in s...
... developed a minimally invasive cryocatheter to ... delivers a very high level of ... site precision, minimal tissue disruption, and ... ,Freezor is a flexible, single-use, minimally ...
The Valve Mapper Steerocath-Dx has a unique "peanut" shaped tip. It is designed to conform to the anatomy during mapping procedures. Both 8F/8mm and 8F/6mm tips are available....
Medicine Products: