Navigation Links
Researchers find anatomic differences after robotic-assisted radical prostatectomy
Date:4/11/2011

(Boston) Researchers from Boston University School of Medicine (BUSM) have concluded that the anatomy of the pelvis following robotic-assisted radical prostatectomy

(RARP) is considerably different when compared to the anatomy of the pelvis following an open prostatectomy (OP). These findings, which are the first to ever compare pelvic anatomy following RARP and OP surgery, may have implications for patients requiring post-operative radiation. The study currently appears on-line in Practical Radiation Oncology.

Prostate cancer is the most common non-cutaneous cancer diagnosed in men globally. In 2009, there were 192,280 new cases diagnosed, and 27,360 deaths from prostate cancer in the U.S. The surgical approaches to prostatectomy include open (OP), laparoscopic, and robot-assisted prostatectomy. In particular, robot-assisted prostatectomy has rapidly gained acceptance in the urologic community and is now in widespread and rapidly expanding use. Currently it is estimated that nearly 60 percent of all prostatectomies in the United States are performed using the robotic technique.

The role of postoperative radiation therapy has been well established. A 1992 randomized, multicenter phase III study by the European Organization for Research and Treatment of Cancer indicated biochemical progression-free survival was statistically significantly improved in the patients treated with adjuvant radiation therapy (74 percent) versus patients treated by radical prostatectomy alone (52.6 percent).

The researchers compared post-operative pelvic MRI scans on consecutive prostatectomy patients (15 RARP and 10 OP) measuring 13 distinct anatomic distances to determine differences in each of the parameters between RARP and OP.

According to the researchers the pelvic anatomy post-RARP is considerably different from the pelvic anatomy post-OP. "The most clinically relevant differences observed in the current study were the superior mediolateral separation of the levator ani and the trend toward statistical significance in the separation of the bladder from the rectum, representing the anterior, posterior, and lateral borders of treatment volumes," explained lead author Ariel Hirsch, MD, an assistant professor of radiation oncology at BUSM "Thus, careful attention must be paid in planning the posterior and lateral margins to ensure that coverage is sufficient in men who have undergone RARP. To that end, our data support that the CTV borders as suggested by the Radiation Therapy Oncology Group guidelines be expanded five mm beyond the anterior rectal wall posteriorly and five mm beyond the levator ani muscles laterally in men who have undergone RARP," she added.

The researchers believe that as RARP continues to become a more widespread surgical option for the management of localized prostate cancer, the radiation field design may need to be further adjusted.


'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to ... to save lost souls in the Philippines. “The Journey: From the Mountains to the ... teacher of the Bible. She has taught all ages and currently teaches a class ...
(Date:10/12/2017)... ... 12, 2017 , ... The company has developed a suite ... regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been developed ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, ...
(Date:10/12/2017)... LOS ANGELES (PRWEB) , ... October 12, 2017 ... ... of Parsa Mohebi Hair Restoration, has recently contributed a medical article to the ... doctors, on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
(Date:10/12/2017)... ... October 12, 2017 , ... Health Literacy Innovations ... literacy software tool, and the Cancer Patient Education Network (CPEN), an independent professional ... announce a new strategic alliance. , As CPEN’s strategic partner, HLI will ...
Breaking Medicine News(10 mins):
(Date:9/23/2017)... HORSHAM, Pa. , Sept. 22, 2017 ... received a complete response letter from the U.S. Food ... (BLA) seeking approval of sirukumab for the treatment of ... response letter indicates additional clinical data are needed to ... of moderately to severely active RA. ...
(Date:9/22/2017)... -- AVACEN Medical (AVACEN) announced that its CE-Marked AVACEN ... with the widespread pain associated with fibromyalgia in the ... Essex, England commented, "I had difficulty ... sleep at all, tremendous pain, with every movement sending ... AVACEN 100] enough, how this has and is helping ...
(Date:9/19/2017)... , Sept. 19, 2017   ZirMed Inc ., ... analytics, today announced that it has been ranked #1 by ... Black Book™ Rankings 2017 User Survey. ZirMed was recognized ... for large hospitals and medical centers over 200 beds and ... Book,s healthcare technology user survey history. ...
Breaking Medicine Technology: