Navigation Links
Researchers find anatomic differences after robotic-assisted radical prostatectomy
Date:4/11/2011

(Boston) Researchers from Boston University School of Medicine (BUSM) have concluded that the anatomy of the pelvis following robotic-assisted radical prostatectomy

(RARP) is considerably different when compared to the anatomy of the pelvis following an open prostatectomy (OP). These findings, which are the first to ever compare pelvic anatomy following RARP and OP surgery, may have implications for patients requiring post-operative radiation. The study currently appears on-line in Practical Radiation Oncology.

Prostate cancer is the most common non-cutaneous cancer diagnosed in men globally. In 2009, there were 192,280 new cases diagnosed, and 27,360 deaths from prostate cancer in the U.S. The surgical approaches to prostatectomy include open (OP), laparoscopic, and robot-assisted prostatectomy. In particular, robot-assisted prostatectomy has rapidly gained acceptance in the urologic community and is now in widespread and rapidly expanding use. Currently it is estimated that nearly 60 percent of all prostatectomies in the United States are performed using the robotic technique.

The role of postoperative radiation therapy has been well established. A 1992 randomized, multicenter phase III study by the European Organization for Research and Treatment of Cancer indicated biochemical progression-free survival was statistically significantly improved in the patients treated with adjuvant radiation therapy (74 percent) versus patients treated by radical prostatectomy alone (52.6 percent).

The researchers compared post-operative pelvic MRI scans on consecutive prostatectomy patients (15 RARP and 10 OP) measuring 13 distinct anatomic distances to determine differences in each of the parameters between RARP and OP.

According to the researchers the pelvic anatomy post-RARP is considerably different from the pelvic anatomy post-OP. "The most clinically relevant differences observed in the current study were the superior mediolateral separation of the levator ani and the trend toward statistical significance in the separation of the bladder from the rectum, representing the anterior, posterior, and lateral borders of treatment volumes," explained lead author Ariel Hirsch, MD, an assistant professor of radiation oncology at BUSM "Thus, careful attention must be paid in planning the posterior and lateral margins to ensure that coverage is sufficient in men who have undergone RARP. To that end, our data support that the CTV borders as suggested by the Radiation Therapy Oncology Group guidelines be expanded five mm beyond the anterior rectal wall posteriorly and five mm beyond the levator ani muscles laterally in men who have undergone RARP," she added.

The researchers believe that as RARP continues to become a more widespread surgical option for the management of localized prostate cancer, the radiation field design may need to be further adjusted.


'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... giving viewers the lowdown on sciatica in a new episode of "Success Files," ... on current events and innovation and investigates each subject in-depth with passion and ...
(Date:10/12/2017)... ... 2017 , ... First Healthcare Compliance (FHC), an industry leader ... range of technology and learning solutions at the 68th Annual American Healthcare Association ... held October 14–18, 2017 at the Mandalay Bay Resort in Las Vegas, Nevada. ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( ... today the introduction of an innovative new design of the shoulder pad. The ... get maximum comfort while controlling your pain while using cold therapy. By utilizing ice ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. ... recently contributed a medical article to the newly revamped Cosmetic Town journal ... spotlights the hair transplant procedure known as Follicular Unit Extraction (FUE). ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... named one of Michigan’s 2017 Best and Brightest in Wellness® by Best and ... Wellness® awards program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  True Health, ... has amplified its effort during National Breast Cancer ... hereditary cancer risks. ... Clinical Oncology calculated that more than 10 million ... inherited mutations in BRCA1 or BRCA2 and have not ...
(Date:10/5/2017)... , Oct. 5, 2017  In response to ... Oral and Maxillofacial Surgeons (AAOMS) released prescribing recommendations ... to be used as a first-line therapy to ... Recognizing the value ... White Paper "Opioid Prescribing: Acute and Postoperative Pain ...
(Date:10/2/2017)... 2, 2017  Eli Lilly and Company (NYSE: ... the third quarter of 2017 on Tuesday, October 24, ... that day with the investment community and media to ... conference call will begin at 9 a.m. Eastern time. ... live webcast of the conference call through a link ...
Breaking Medicine Technology: