Navigation Links
Researchers find CDT biomarker ineffective for identifying unhealthy alcohol use
Date:6/20/2011

(Boston) Researchers from Boston University School of Medicine (BUSM) have found that among HIV-infected adults with alcohol problems, measuring their carbohydrate-deficient transferrin (CDT) biomarker was a poor and inaccurate method for detecting unhealthy drinking. These findings currently appear on-line in AIDS Care.

Unhealthy alcohol use is common in HIV-infected persons. It can interfere with HIV medication adherence, may lower CD4 cell count and can cause hepatic injury. Furthermore, HIV co-infection with viral hepatitis is common and both HIV and viral hepatitis are adversely impacted by alcohol. For these reasons, detection of unhealthy alcohol use is important in the clinical care of HIV-infected individuals.

Some clinicians are interested in having a laboratory test that can detect unhealthy alcohol use. Although CDT, often measured as %CDT, can detect very heavy drinking, whether it does so in people with HIV in a clinically useful manner has yet to be established. The researchers evaluated the ability of %CDT and gamma glutamyltransferase to detect three levels of unhealthy alcohol consumption: "at-risk", "heavy" and "frequent heavy" drinking as determined by the reference standard Timeline Followback questionnaire.

Of the 300 subjects, 103 reported current consumption at "at-risk" amounts, and 47 reported "heavy" amounts. For "at-risk" drinking, sensitivity of %CDT was 28 percent, meaning the test detected only 28 percent of those with unhealthy alcohol use. For "heavy" drinking, sensitivity was 36 percent. According to the researchers, these findings suggest that %CDT is not sufficiently sensitive for use in screening for unhealthy alcohol use by people with HIV infection.

"There is evidence that early intervention for unhealthy alcohol use can be effective but early clinical signs are often missed and unhealthy alcohol use often goes undiagnosed by HIV healthcare providers," explained principal inve
'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Mayo Clinic researchers use human vaccine to cure prostate cancer in mice
2. UT Southwestern researchers uncover why ketamine produces a fast antidepressant response
3. Researchers report progress using iPS cells to reverse blindness
4. Researchers warn of fever from the forest
5. NIH researchers find new clues about aging
6. Routine screening for autism not needed: McMaster researchers
7. Researchers work to turn back the clock on bone-producing stem cells
8. U-M researchers advocate national strategic approach to therapeutic cancer vaccines
9. Rhode Island and Miriam researchers say patient gender may influence nuclear stress test referrals
10. Researchers discover biochemical weakness of malaria parasite -- vaccine to be developed
11. Researchers find that inhibiting microRNAs may help prevent degenerative eye disorders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/4/2015)... and Dayton, Ohio (PRWEB) March 04, 2015 ... killed in an IED explosion in Iraq, tells you ... recovering. He received some free Chiropractic care from the ... Magnetic Resonance Therapy. , This is what Harris said ... the Magnesphere, I have clarity, I feel more calm, ...
(Date:3/4/2015)... CA (PRWEB) March 04, 2015 ... have been selected by Chase Brexton Health Care, ... announced today. , Chase Brexton provides comprehensive primary ... than 30,000 patients across seven clinics in the ... adopters of electronic medical records, the organization has ...
(Date:3/4/2015)... Jose, California (PRWEB) March 04, 2015 ... CNS therapeutics market is driven by the increasing incidence ... an encouraging pipeline of late stage drugs. The unmet ... to fore the untapped potential in the market. Presently, ... effective drugs that overcome the limitations of current generation ...
(Date:3/4/2015)... 04, 2015 Follow us on ... enhancing the appearance of the skin and body, are ... of therapeutic agents to achieve the desired product properties ... society obsessed with physical beauty, youth, and achievement. Demand ... and sales of cosmetics. Growth in the market is ...
(Date:3/4/2015)... Ada Products Company, Inc ., an ... strategic partnership with the Dental Exchange in an effort ... them to engaging, inspiring ideas, products, career opportunities, and ... Dental Exchange is a first-of-its kind online resource ... other social platforms, the Dental Exchange dives much deeper ...
Breaking Medicine News(10 mins):Health News:Decorated Veterans Endorse “Halos for Heroes” an Indiegogo campaign to Help Wounded Military Heal at Home 2Health News:Decorated Veterans Endorse “Halos for Heroes” an Indiegogo campaign to Help Wounded Military Heal at Home 3Health News:Chase Brexton Selects i2i Systems Population Health Management Solutions to Demonstrate HEDIS Quality Outcomes to Maryland’s Health Plans 2Health News:Chase Brexton Selects i2i Systems Population Health Management Solutions to Demonstrate HEDIS Quality Outcomes to Maryland’s Health Plans 3Health News:Rising Incidence of CNS Disorders & a Promising Global Drug Pipeline Drive the CNS Therapeutics Market, According to a New Report by Global Industry Analysts, Inc. 2Health News:Rising Incidence of CNS Disorders & a Promising Global Drug Pipeline Drive the CNS Therapeutics Market, According to a New Report by Global Industry Analysts, Inc. 3Health News:Rising Incidence of CNS Disorders & a Promising Global Drug Pipeline Drive the CNS Therapeutics Market, According to a New Report by Global Industry Analysts, Inc. 4Health News:Rising Demand for Anti-Aging & Skincare Cosmeceuticals to Drive the Global Cosmetic Chemicals Market, According to a New Report by Global Industry Analysts, Inc. 2Health News:Rising Demand for Anti-Aging & Skincare Cosmeceuticals to Drive the Global Cosmetic Chemicals Market, According to a New Report by Global Industry Analysts, Inc. 3Health News:Rising Demand for Anti-Aging & Skincare Cosmeceuticals to Drive the Global Cosmetic Chemicals Market, According to a New Report by Global Industry Analysts, Inc. 4Health News:Ada Products Company, Inc. Announces Strategic Partnership with the Dental Exchange 2
... University of South Florida Department of Neurosurgery and Brain ... from the National Institutes of Health to investigate the ... benefit post-stroke patients by repairing the blood-brain barrier (BBB). ... entering the brain while allowing passage of needed substances. ...
... different alcoholic beverages and drinking behaviour on the risk of ... Cohort of Swedish Men, to study the association between consumption ... pancreatitis. In total, 84,601 individuals, aged 46-84 years, were ... developed acute pancreatitis. There was a doseresponse association between ...
... (HealthDay News) -- What do a prehistoric water reptile ... than you might expect, new research indicates. A ... its embryo offers the first evidence of live birth ... have had a social structure similar to modern dolphins, ...
... Electrodiagnostic Medicine (AANEM) has awarded accreditation status to four ... Neuromuscular Center in Northeast Ohio. The EMG labs ... Ahuja Medical Center in Beachwood, Oh., UH University Suburban ... Health Center in Westlake, Oh., received accreditation. UH Case ...
... isolating cells from patients, spinal tissue within a few days ... have developed a new model of the paralyzing disease amyotrophic ... cells called astrocytes become toxic to nerve cells a ... The new model could be used to investigate many ...
... , THURSDAY, Aug. 11 (HealthDay News) -- Symptoms ... people over 80, according to a new study that ... memory loss. The study included 105 Alzheimer,s patients ... age, those 60 to 75 (young-old) and those 80 ...
Cached Medicine News:Health News:USF researchers get $2.6 million NIH grant to investigate new post-stroke therapy 2Health News:Alcohol consumption in relation to acute pancreatitis 2Health News:Prehistoric Water Reptile's Social Life Similar to Dolphins: Study 2Health News:New model of ALS is based on human cells from autopsied tissue 2Health News:New model of ALS is based on human cells from autopsied tissue 3Health News:New model of ALS is based on human cells from autopsied tissue 4Health News:Alzheimer's Harder to Detect in the Very Old 2
(Date:3/4/2015)... , March 4, 2015  Results of the ... Consecutive Cases Using MarginProbe for Intra-Operative Positive Margin Detection ... session at the 32 nd Annual Miami Breast ... conducted by Moshe Papa , MD, FACS, Professor ... Tel Aviv University, reports an analysis of MarginProbe,s efficiency ...
(Date:3/4/2015)... N.J. , March 4, 2015  Bayer ... Drug Administration (FDA) has accepted the company,s Biologics ... Factor VIII compound.  Bayer is seeking FDA approval ... for the treatment of hemophilia A in children ... to continually bringing new therapies to hemophilia A ...
(Date:3/4/2015)... March 4, 2015  Heska Corporation (Nasdaq: ... You to Join Its Fourth Quarter and Year End ... 2015 @ 9:00 a.m. (MST) / 11:00 a.m. (EST)Where: ... 2014 Earnings Call link on the front page of ... to the web at the address above.  Alternatively, you ...
Breaking Medicine Technology:New Study Shows Breast Re-excision Rates Significantly Reduced in 100 Consecutive Cases 2FDA Accepts Bayer's Biologics License Application for Investigational Treatment Option in Hemophilia A 2FDA Accepts Bayer's Biologics License Application for Investigational Treatment Option in Hemophilia A 3Webcast Alert: Heska Announces Fourth Quarter and Year End 2014 Earnings Conference Call Webcast 2
... Corporation (OTC Bulletin Board: CONX), a worldwide developer and marketer ... the first fiscal quarter ended September 30, 2009, compared with ... of 2.2%. , The first quarter of fiscal 2010 produced ... $94,133 for the first quarter of fiscal 2009. The net ...
... 12 A new software technology is helping to ... by electronically identifying the sperm, eggs, resulting embryos and ... (IVF) treatment cycles. Using non-invasive Radio Frequency Identification (RFID), ... embryos during the course of treatment. If the wrong ...
Cached Medicine Technology:Corgenix Reports Financial Results for First Quarter of Fiscal 2010 2Corgenix Reports Financial Results for First Quarter of Fiscal 2010 3New Technology Reduces Risk of IVF Laboratory Mistakes by Electronically Identifying Sperm, Eggs and Other Materials for Each Patient 2New Technology Reduces Risk of IVF Laboratory Mistakes by Electronically Identifying Sperm, Eggs and Other Materials for Each Patient 3
Inquire...
Sealing Mat for 96-well, 2.0ml, Deep Well, Square Available Sterile...
Silicone Compression Mat, Bulk...
MicroAmp Full Plate Covers, which are manufactured from PCR-compatible rubber, are non-sterile, autoclavable and guaranteed reusable up to five times....
Medicine Products: