Navigation Links
Researchers find CDT biomarker ineffective for identifying unhealthy alcohol use
Date:6/20/2011

(Boston) Researchers from Boston University School of Medicine (BUSM) have found that among HIV-infected adults with alcohol problems, measuring their carbohydrate-deficient transferrin (CDT) biomarker was a poor and inaccurate method for detecting unhealthy drinking. These findings currently appear on-line in AIDS Care.

Unhealthy alcohol use is common in HIV-infected persons. It can interfere with HIV medication adherence, may lower CD4 cell count and can cause hepatic injury. Furthermore, HIV co-infection with viral hepatitis is common and both HIV and viral hepatitis are adversely impacted by alcohol. For these reasons, detection of unhealthy alcohol use is important in the clinical care of HIV-infected individuals.

Some clinicians are interested in having a laboratory test that can detect unhealthy alcohol use. Although CDT, often measured as %CDT, can detect very heavy drinking, whether it does so in people with HIV in a clinically useful manner has yet to be established. The researchers evaluated the ability of %CDT and gamma glutamyltransferase to detect three levels of unhealthy alcohol consumption: "at-risk", "heavy" and "frequent heavy" drinking as determined by the reference standard Timeline Followback questionnaire.

Of the 300 subjects, 103 reported current consumption at "at-risk" amounts, and 47 reported "heavy" amounts. For "at-risk" drinking, sensitivity of %CDT was 28 percent, meaning the test detected only 28 percent of those with unhealthy alcohol use. For "heavy" drinking, sensitivity was 36 percent. According to the researchers, these findings suggest that %CDT is not sufficiently sensitive for use in screening for unhealthy alcohol use by people with HIV infection.

"There is evidence that early intervention for unhealthy alcohol use can be effective but early clinical signs are often missed and unhealthy alcohol use often goes undiagnosed by HIV healthcare providers," explained principal inve
'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Mayo Clinic researchers use human vaccine to cure prostate cancer in mice
2. UT Southwestern researchers uncover why ketamine produces a fast antidepressant response
3. Researchers report progress using iPS cells to reverse blindness
4. Researchers warn of fever from the forest
5. NIH researchers find new clues about aging
6. Routine screening for autism not needed: McMaster researchers
7. Researchers work to turn back the clock on bone-producing stem cells
8. U-M researchers advocate national strategic approach to therapeutic cancer vaccines
9. Rhode Island and Miriam researchers say patient gender may influence nuclear stress test referrals
10. Researchers discover biochemical weakness of malaria parasite -- vaccine to be developed
11. Researchers find that inhibiting microRNAs may help prevent degenerative eye disorders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2015)... (PRWEB) May 03, 2015 It is not too ... Brain Aneurysm Walk in Memory of Lissa Anne Been in ... organized this great family-friendly event to honor her loving memory. It ... inception. , Just having turned 37, Lissa suffered a ... away on August 24, 2012. This event is designed to serve ...
(Date:5/2/2015)... As one of only 30 Illinois ... and Health Achievement and Recognition Program (SHARP) certification, ... by the Illinois Department of Labor to host this ... SHARP certification by the Occupational Safety and Health Administration’s ... continued to meet or exceed all of the necessary ...
(Date:5/2/2015)... Vancouver fencing company, QS Fencing, has recently announced that its ... related to their questions on railings and gates. Many people ... and patios. While that seems like an easy task, there ... rolls up their sleeve to start working. One of the ... gate that matches it. , Instead of spending hours worrying ...
(Date:5/2/2015)... ProText Kinetic 2 is a set of ... Pro X. ProText Kinetic 2 features 40 animation ... Pro X . Easily create interactive text videos without ... ProText Kinetic 2. , Using ProText Kinetic is as easy ... Kinetic presets in the FCPX timeline. Playback the default ...
(Date:5/2/2015)... We are pleased to announce the ... as one of the Top Workplaces of 2015. , ... treatment field for their ethics and standards of excellence. ... continue their educational efforts. The Delray Recovery Center prides ... their purpose – to help individuals heal from the ...
Breaking Medicine News(10 mins):Health News:Renowned Brain Aneurysm Foundation to Benefit from Arnold, Missouri’s 3rd Annual Brain Aneurysm Walk in Memory of Lissa Anne Been 2Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 2Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 3Health News:Professional Staff at QS Fencing Company Now Provides Advice on Railings and Gates 2Health News:Pixel Film Studios Announced the Release of Protext Kinetic 2 for FPCX. 2Health News:The Delray Recovery Center Named 2015 Top Workplace 2
... Nov. 6 Those biopharmaceutical companies that are ... their business models will be best positioned to ... according to a white paper published today by ... equity firm, and Health Advances, a leading healthcare ...
... 6 Bulletproof Blog , the ... with former Speaker of the U.S. House of Representatives ... to effect America,s business landscape. , In the interview, ... impacting the crossroads of business and government, including healthcare ...
... Nov. 6 Allied World Assurance,Company Holdings, Ltd ... World U.S.,Nicole Baummer, Assistant Vice President for Private/Not-for-Profit ... Lines,Claims, will be speaking at this year,s Professional ... in Chicago, Illinois,November 11-13, 2009. , ...
... 6 We Work for Health, an alliance of ... released the results of a first-of-its-kind economic impact study ... passed many of the traditional resource-based industries on which ... same range of importance as some of the new, ...
... Nov. 6 The current health care debate in the ... choices and life expectancy have been suggested but seldom clearly ... year on health care for every 80 year old, while ... octogenarians have a 20 percent less chance of dying than ...
... food choices in study , FRIDAY, Nov. 6 (HealthDay News) ... choices, researchers say. , The new study included 542 male ... irregular shifts. The average age of the participants was 49, ... sleep medicine division at Harvard Medical School found that adequate ...
Cached Medicine News:Health News:Surviving Healthcare Reform: How Biopharma Companies Can Come Out on Top 2Health News:Former House Speaker Newt Gingrich Shares Insights on Healthcare Reform and the Federal Pay Czar with BulletproofBlog.com 2Health News:Allied World's Nicole Baummer and Marjorie Thompson to Speak at PLUS International Conference 2Health News:Allied World's Nicole Baummer and Marjorie Thompson to Speak at PLUS International Conference 3Health News:New Study: Life Science Jobs Total 77,000 in Washington State 2Health News:New Study: Life Science Jobs Total 77,000 in Washington State 3Health News:Carnegie Mellon Researcher Links Health Care Debate to Risk of Dying in the U.S. and Europe 2Health News:Carnegie Mellon Researcher Links Health Care Debate to Risk of Dying in the U.S. and Europe 3Health News:Carnegie Mellon Researcher Links Health Care Debate to Risk of Dying in the U.S. and Europe 4
(Date:5/1/2015)... May 1, 2015 The breakthrough hepatitis C ... price but manufacturer Gilead Sciences overcame initial market resistance ... effective public relations campaigns. Sovaldi,s high cure ... side effects propelled the drug to $2.3 billion in ... first quarter on the market. But Sovaldi,s price tag ...
(Date:5/1/2015)... 2015 CANTEL MEDICAL CORP. (NYSE: CMN ) ... Officer, will be presenting at the Bank of America Merrill ... in Las Vegas, NV. The formal ... AM PT/1:00 PM ET. In addition, management will be available ... An audio webcast will be available via the investor relations ...
(Date:5/1/2015)... May 01, 2015 Research and Markets ... "US ACO IT Spending Outlook 2018" report ... number of lives covered by ACO would grow at ... report, the ACO IT spending has been studied on ... software and spending on services. Our research provides current ...
Breaking Medicine Technology:New Study Examines Success Lessons of Sovaldi's and Harvoni's Blockbuster Launches 2United States ACO IT Spending Outlook 2014-2018 2
... level of injury is key to treating MCLs nonsurgically, ... to the knee,s medial cruciate ligament (MCL) may be ... published in the March 2009 issue of The ... (JAAOS) . The key, the review,s authors found, ...
... 2 Aerovance Inc. today announced that it ... Drug Administration (FDA) and the U.K. Medicines and ... Phase IIb clinical trial, AeroTrial(TM), of inhaled dry ... begins today in the United States for AeroTrial, ...
Cached Medicine Technology:Treating Knee Ligament Injuries 2Treating Knee Ligament Injuries 3Aerovance Initiates Phase IIb Clinical Trial with Aerovant(TM) for the Treatment of Uncontrolled Asthma 2Aerovance Initiates Phase IIb Clinical Trial with Aerovant(TM) for the Treatment of Uncontrolled Asthma 3
High viscosity bone cement without antibiotics for digital use with an average setting time of approx. 6-8 Min., 40g of powder and 14.4g of liquid....
... The Videoscopes provide superior image ... connecting to the camera head with ... density ensures more light at the ... provide optimum image clarity and reliability.,The ...
... Nail System sports a 2mm mid-shaft ... support and stability of a large ... preserves diaphyseal bone stock in the ... fracture routinely associated with the use ...
... is the second generation of the lens ... technology allows one-handed delivery of the C11UB ... colored plunger allows better visualization and is ... insertion. The modified 55-degree beveled tip eases ...
Medicine Products: