Navigation Links
Researchers explore the emerging role of infection in Alzheimer's disease
Date:5/22/2008

May 22, 2008, Amsterdam A number of chronic diseases are in fact caused by one or more infectious agents. For example, stomach ulcers are caused by Helicobacter pylori, chronic lung disease in newborns and chronic asthma in adults are both caused by Mycoplasmas and Chlamydia pneumonia, while some other pathogens have been associated with atherosclerosis. The realization that pathogens can produce slowly progressive chronic diseases has opened new lines of research into Alzheimers disease.

In a special issue of the Journal of Alzheimers Disease published May 2008, guest editors Judith Miklossy, from The University of British Columbia, and Ralph N. Martins, from Edith Cowan University and Hollywood Private Hospital, Perth, Western Australia, and a group of experts explore this exciting topic.

Alzheimers disease (AD), the most frequent cause of dementia, is a form of amyloidosis. It has been known for a century that dementia, brain atrophy and amyloidosis can be caused by chronic bacterial infections, namely by Treponema pallidum in the atrophic form of general paresis in syphilis. Bacteria and viruses are powerful stimulators of inflammation. It was suggested by Alois Alzheimer and his colleagues a century ago that microorganisms may be contributors in the generation of senile plaques in AD.

The fact that pathogens may suppress, subvert or evade host defenses and establish chronic or latent infection has received little attention in the past. During infection, active oxygen and nitrogen species generated by inflammatory cells may cause DNA damage, induce apoptosis, and modulate enzyme activities and gene expression. Depending upon the biology of the pathogen and the host defense mechanisms the organism can persist in the infected tissues and cause chronic inflammation and amyloid deposition. The outcome of infection is as much determined by the genetic predisposition of the patient as by the virulence and biology of the infecting agent
'/>"/>

Contact: Astrid Engelen
a.engelen@iospress.nl
31-206-883-355
IOS Press
Source:Eurekalert

Page: 1 2

Related medicine news :

1. 2 LA BioMed researchers named Heroes of Emergency Medicine
2. Virtual biopsy can tell whether colon polyp is benign without removal, Mayo researchers say
3. Researchers close in on new melanoma gene
4. Traditional herbal medicine kills pancreatic cancer cells, Jefferson researchers report
5. Researchers develop first transgenic monkey model of Huntingtons disease
6. Researchers expand natural killer cells in cord blood to fight leukemia
7. Medical College of Wisconsin researchers identify proteins that help develop mammalian hearts
8. Mastectomies on the rise and MRI use may explain part of the trend, say Mayo researchers
9. UCSD researchers show link between vitamin D status, breast cancer
10. Researchers find first conclusive evidence of Alzheimers-like brain tangles in nonhuman primates
11. Vancouver researchers discover missing link between TB bacteria and humans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2015)... In observance of World Malaria Day, ... Nets Pledge, a two-year pledge by the United Nations ... with one million bednets by 2016. This ambitious $10 ... partners to protect children, refugees, and families displaced by ... has been a large surge in refugee families displaced ...
(Date:4/25/2015)... (PRWEB) April 25, 2015 The Hon. ... Worker Safety issues the following statement following the deadly ... hit Kathmandu, Nepal, resulting in the deaths of more ... earthquake were felt across Nepal, Bangladesh, India and other ... my heartfelt condolences to the people of Nepal and ...
(Date:4/25/2015)... New Jersey (PRWEB) April 25, 2015 ... people aged twelve and above needed treatment for an ... according to the Substance Abuse and Mental Health Services ... September 2011). Beyond these alarming numbers are harrowing stories ... by substance abuse . David H. Kerr ...
(Date:4/25/2015)... April 25, 2015 The federal ... mesh lawsuits filed against C.R. Bard, Inc. continues ... Southern District of West Virginia. According to a ... was convened that day, after certain defendants submitted ... Complaint. The Order directed that any Preliminary Motions ...
(Date:4/25/2015)... Carinsurancequotesinfo.com has released a new blog post that ... for flatbed trucks. , Flatbed trucks are ... They are mainly used for commercial purposes and thus ... explains that by comparing multiple offers, drivers can find ... vehicles. , It is now possible to compare free ...
Breaking Medicine News(10 mins):Health News:Supporters Worldwide Join The Million Nets Pledge on World Malaria Day 2Health News:Supporters Worldwide Join The Million Nets Pledge on World Malaria Day 3Health News:Supporters Worldwide Join The Million Nets Pledge on World Malaria Day 4Health News:New Book Features Powerful Stories of People Who Overcame Addiction 2Health News:New Book Features Powerful Stories of People Who Overcame Addiction 3Health News:C.R. Bard Vaginal Mesh Lawsuit News: Federal Litigation Issues New Pretrial Order Following Submission of Amended Responses to Master Complaint 2Health News:C.R. Bard Vaginal Mesh Lawsuit News: Federal Litigation Issues New Pretrial Order Following Submission of Amended Responses to Master Complaint 3Health News:C.R. Bard Vaginal Mesh Lawsuit News: Federal Litigation Issues New Pretrial Order Following Submission of Amended Responses to Master Complaint 4Health News:Auto Insurance Quotes for Flatbed Trucks Available Online! 2
... Schizophrenia may blur the boundary between internal and external ... in self-reflection, and thus causing an exaggerated focus on ... has found. , The traditional view of schizophrenia ... characterize the disease are caused by disconnections among the ...
... aids can offer hope of better hearing for people ... conducted by the non-profit educational organization Better Hearing Institute ... the United States and Canada found that six out ... when using hearing aids and two of ten reported ...
... to Customers , LANDOVER, Md., Jan. 21 Recently, ... containing peanut butter and peanut paste from their shelves. ... salmonella to a plant owned by Peanut Corporation of ... our shelves including:, , ...
... influence medical care and research that demonstrates how science ... the list of cardiovascular disease and stroke advances from ... Heart Association.The American Heart Association has been compiling an ... heart disease and stroke research since 1996."It,s always difficult ...
... controls winter in Northern Hemisphere , , WEDNESDAY, Jan. 21 (HealthDay ... open earlier in the spring, and birds are migrating sooner, ... worldwide temperatures been rising for the last 50 years, but ... days earlier. , That,s the conclusion of a new ...
... A new study appearing in The Prostate has ... strain known as MV-CEA, may prove to be an effective ... that this type of treatment, called virotherapy, can effectively infect, ... cancer is a leading cause death among males in the ...
Cached Medicine News:Health News:Altered brain activity in schizophrenia may cause exaggerated focus on self 2Health News:Altered brain activity in schizophrenia may cause exaggerated focus on self 3Health News:Hearing Aids Offer Hope for Those Who Suffer from Persistent 'Ringing in the Ears,' Better Hearing Institute Survey Finds 2Health News:Hearing Aids Offer Hope for Those Who Suffer from Persistent 'Ringing in the Ears,' Better Hearing Institute Survey Finds 3Health News:Hearing Aids Offer Hope for Those Who Suffer from Persistent 'Ringing in the Ears,' Better Hearing Institute Survey Finds 4Health News:Giant Food Responds to Recall of Peanut Based Products 2Health News:American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities 2Health News:American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities 3Health News:American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities 4Health News:American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities 5Health News:American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities 6Health News:American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities 7Health News:American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities 8Health News:American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities 9Health News:American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities 10Health News:Seasons Arriving 2 Days Earlier, Study Says 2Health News:Measles virus may be effective prostate cancer treatment 2
(Date:4/25/2015)... April 2015 Hospira, Inc. ... Entwicklung von Biosimilar-Behandlungen, sprach heute auf der jährlichen ... (EGA) in London über ... Verfügbarkeit von Biosimilars für Patienten. Das ... Papers mit dem Titel „Why extrapolation is ...
(Date:4/25/2015)... -- With the introduction of Elekta,s new Leksell Gamma Knife® ... available for more patients with a wider variety of ... system for the brain, integrates advanced motion management, dose ... Gamma Knife radiosurgery. Elekta unveiled Leksell Gamma Knife Icon ... Barcelona . "This is ...
(Date:4/24/2015)... , und BARCELONA , ... Nr. 4410) iCAD, Inc. (Nasdaq: ICAD ... Bildanalyse, Lösungen für Behandlungsabläufe und Strahlentherapie für ... heute die sofortige Verfügbarkeit des ersten Xoft ... (eBx ® ) System ® in ...
Breaking Medicine Technology:Führungskräfte von Hospira präsentieren auf bedeutendem europäischen Biosimilars-Forum - Ankündigung eines White Papers über Extrapolation 2Führungskräfte von Hospira präsentieren auf bedeutendem europäischen Biosimilars-Forum - Ankündigung eines White Papers über Extrapolation 3Führungskräfte von Hospira präsentieren auf bedeutendem europäischen Biosimilars-Forum - Ankündigung eines White Papers über Extrapolation 4Führungskräfte von Hospira präsentieren auf bedeutendem europäischen Biosimilars-Forum - Ankündigung eines White Papers über Extrapolation 5Führungskräfte von Hospira präsentieren auf bedeutendem europäischen Biosimilars-Forum - Ankündigung eines White Papers über Extrapolation 6Führungskräfte von Hospira präsentieren auf bedeutendem europäischen Biosimilars-Forum - Ankündigung eines White Papers über Extrapolation 7Führungskräfte von Hospira präsentieren auf bedeutendem europäischen Biosimilars-Forum - Ankündigung eines White Papers über Extrapolation 8New Leksell Gamma Knife to benefit more patients with brain disease 2New Leksell Gamma Knife to benefit more patients with brain disease 3Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 2Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 3Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 4Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 5Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 6
... NASHVILLE, Tenn. , April 26 Cumberland Pharmaceuticals Inc. ... preference study evaluating Kristalose® ( lactulose ) for Oral Solution, a prescription ... Digestive Disease Week® meeting in New Orleans .   , ... A poster presentation of the study, ...
... DIEGO , April 26 Neurocrine Biosciences, Inc. (Nasdaq: NBIX ... of Neurocrine Biosciences, will be presenting at the Deutsche Bank 35th Annual Health ... , , ... 10:00 a.m. Eastern Time / 7:00 a.m. Pacific Time . ...
Cached Medicine Technology:Kristalose(R) Clinical Data to Be Presented at Digestive Disease Week(R) Meeting 2Kristalose(R) Clinical Data to Be Presented at Digestive Disease Week(R) Meeting 3Neurocrine Biosciences to Present at the Deutsche Bank 35th Annual Health Care Conference 2
... The patented ratchet design provides fingertip ... ,The Series I Instrument program offers state-of-the-art ... profile, while maintaining strength and durability. Low ... in tight joint spaces. Series I instruments ...
... A broad selection of procedurally specific ... and allow easy access to all ... variety of approaches.,Loop Handled Graspers feature ... holds tissue firmly without tearing or ...
... of procedurally specific tip configurations provide ... access to all areas of the ... Handled Graspers feature an "infinite position ... without tearing or slipping even ...
...
Medicine Products: