Navigation Links
Researchers explore the emerging role of infection in Alzheimer's disease
Date:5/22/2008

May 22, 2008, Amsterdam A number of chronic diseases are in fact caused by one or more infectious agents. For example, stomach ulcers are caused by Helicobacter pylori, chronic lung disease in newborns and chronic asthma in adults are both caused by Mycoplasmas and Chlamydia pneumonia, while some other pathogens have been associated with atherosclerosis. The realization that pathogens can produce slowly progressive chronic diseases has opened new lines of research into Alzheimers disease.

In a special issue of the Journal of Alzheimers Disease published May 2008, guest editors Judith Miklossy, from The University of British Columbia, and Ralph N. Martins, from Edith Cowan University and Hollywood Private Hospital, Perth, Western Australia, and a group of experts explore this exciting topic.

Alzheimers disease (AD), the most frequent cause of dementia, is a form of amyloidosis. It has been known for a century that dementia, brain atrophy and amyloidosis can be caused by chronic bacterial infections, namely by Treponema pallidum in the atrophic form of general paresis in syphilis. Bacteria and viruses are powerful stimulators of inflammation. It was suggested by Alois Alzheimer and his colleagues a century ago that microorganisms may be contributors in the generation of senile plaques in AD.

The fact that pathogens may suppress, subvert or evade host defenses and establish chronic or latent infection has received little attention in the past. During infection, active oxygen and nitrogen species generated by inflammatory cells may cause DNA damage, induce apoptosis, and modulate enzyme activities and gene expression. Depending upon the biology of the pathogen and the host defense mechanisms the organism can persist in the infected tissues and cause chronic inflammation and amyloid deposition. The outcome of infection is as much determined by the genetic predisposition of the patient as by the virulence and biology of the infecting agent
'/>"/>

Contact: Astrid Engelen
a.engelen@iospress.nl
31-206-883-355
IOS Press
Source:Eurekalert

Page: 1 2

Related medicine news :

1. 2 LA BioMed researchers named Heroes of Emergency Medicine
2. Virtual biopsy can tell whether colon polyp is benign without removal, Mayo researchers say
3. Researchers close in on new melanoma gene
4. Traditional herbal medicine kills pancreatic cancer cells, Jefferson researchers report
5. Researchers develop first transgenic monkey model of Huntingtons disease
6. Researchers expand natural killer cells in cord blood to fight leukemia
7. Medical College of Wisconsin researchers identify proteins that help develop mammalian hearts
8. Mastectomies on the rise and MRI use may explain part of the trend, say Mayo researchers
9. UCSD researchers show link between vitamin D status, breast cancer
10. Researchers find first conclusive evidence of Alzheimers-like brain tangles in nonhuman primates
11. Vancouver researchers discover missing link between TB bacteria and humans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/30/2015)... 2015 The iconic American actor, and ... hosting a new segment on Medical Malpractice. This segment ... malpractice in the health care field. , According to ... medical malpractice suits were filed, roughly only 20% of ... out of court, while the remaining 30% were tossed ...
(Date:5/30/2015)... “ Milli the Snail ” was featured ... a look at the latest and coolest applications on the ... of AppWatch and technology expert, conducted the app review and ... engages and educates children. , Interactive mobile games for children ... content and games they are playing are doing much for ...
(Date:5/30/2015)... Nevada (PRWEB) May 30, 2015 Venus ... of acne scars, large pores, deep wrinkles, stretch marks, ... licensed medical professional, such as Dr. F. Victor Rueckl ... of the clinical trials in Las Vegas. This body ... technology into a system that delivers proven results through ...
(Date:5/29/2015)... CA (PRWEB) May 29, 2015 Displays and ... that has lowered the price of hanging signs ; ... Hanging signs that hang down from ceiling rigging points at ... over the trade show floor. These signs are very ... there are additional costs for installation and dismantle labor and ...
(Date:5/29/2015)... May 29, 2015 Based in St. Louis, ... awareness shirts for a couple of months now and ... latest release, which reads “I’m not misbehaving, I have Autism, ... the parent’s of an autistic child in order to start ... , Not only are they raising awareness through the autism ...
Breaking Medicine News(10 mins):Health News:An Aesthetic Game that Engages and Educates Children was Featured on NewsWatch Television 2Health News:Announcing Ground-Breaking Technology for Anti-Aging, FDA Approved, Venus Viva. 2Health News:Announcing Ground-Breaking Technology for Anti-Aging, FDA Approved, Venus Viva. 3Health News:Displays and Exhibits Announces New Hanging Sign Supplier 2Health News:La La Land Shirts Is Busy Spreading Autism Awareness with Complimentary Shipping on Their New Shirt 2
... uninsured accounted for almost 1 out of 5 ... -- An estimated 50 million, or 42 percent, of ... hospital emergency departments were billed to the Medicaid and ... Thursday. , Uninsured patients accounted for nearly 18 percent ...
... , , ABA program will ... CALDWELL, N.J., July 31 Caldwell College will launch the ... (ABA), a well developed scientific discipline that is best known for ... Caldwell,s program was recently approved by the New Jersey Commission ...
... July 31 /PRNewswire-FirstCall/ - Hard to Treat Diseases,Inc. (HTDS:PK), ... MEVAC-DTaP (Diphtheria, Tetanus and Acellular,Pertussis Combined Vaccine, adsorbed) had ... The sample analysis is expected to be completed,within the ... Terry Yuan CEO of HTDS said (sic) "We welcome ...
... 31 As the world prepares for a probable ... Pittsburgh researchers are controlling the spread of infectious diseases ... (NIH) grant to establish a Center of Excellence in ... the NIH,s Modeling of Infectious Disease Agent Study (MIDAS) ...
... July 31, 2009 Raytheon Company (NYSE: RTN ... public health-led team of first responders and hospital personnel in ... information. , , The EPTS, ... of victims during mass casualty incidents by providing selected patient ...
... expect meds to relieve stress, personal troubles, researchers caution, ... growing number of Americans now have a positive opinion ... About five out of six people surveyed felt psychiatric ... also expected the medications could help people deal with ...
Cached Medicine News:Health News:ER Visits Mostly by Medicare, Medicaid Recipients 2Health News:Caldwell College Receives Approval to Launch First Ph.D. for Applied Behavior Analysis-Autism Treatment in New Jersey 2Health News:Hard to Treat Diseases, Inc. (HTDS) Thai Registration Dossier 2Health News:Hard to Treat Diseases, Inc. (HTDS) Thai Registration Dossier 3Health News:Pitt receives $13.4 million NIH grant to create virtual models for epidemics 2Health News:Raytheon to Provide California First Responders and Healthcare Personnel Electronic Patient Tracking System 2Health News:Psych Drugs Gaining Widespread Acceptance 2Health News:Psych Drugs Gaining Widespread Acceptance 3
(Date:5/29/2015)... 29, 2015 LifeNet Health plans to enlarge ... 2015 to more than 160 people. The ... LifeNet Health,s innovative bio-implants, which are being made more ... be served. It also is a reflection of the ... "The growth and success of LifeNet Health is a ...
(Date:5/29/2015)... ON , May 29, 2015 /CNW/ - Covalon ... an advanced medical technologies company, is delighted to ... ended March 31, 2015, which includes revenue for ... the quarter of $264,340. Revenue from advanced wound care ... March 31, 2015 increased 24% to $1,742,672 compared ...
(Date:5/29/2015)... May 29, 2015  Epic Sciences announced today that ... from metastatic castrate resistant prostate cancer patients, at ... for Clinical Oncology. This application expands the investigational ... behind™ platform to characterize circulating tumor cell ... stage patients have heterogeneous clonal CTC populations harboring ...
Breaking Medicine Technology:LifeNet Health to add more than 160 jobs in 2015 2Covalon Announces Strong Second Quarter Results 2Covalon Announces Strong Second Quarter Results 3Genetic Analysis of Single Circulating Tumor Cells Shows High Intra-patient Heterogeneity 2Genetic Analysis of Single Circulating Tumor Cells Shows High Intra-patient Heterogeneity 3
Shepard tying forceps, round curved platform 8 mm, 8.5 cm....
Girard angled tying forceps made of titanium has angled 45 shafts with 4 mm tying platforms, width of shafts 0,25 mm, TCI platforms, round handle, diam. 6 mm, overall length 102 mm....
Curved tying forceps made of titanium has curved shafts with 6 mm V-grove tying platforms, width of shafts 0,5 mm, TCI platforms, flat handle, width 10 mm, overall length 103 mm....
McPherson angled tying forceps made of titanium tying forceps, angled 45 shafts with 6 mm tying platforms, width of shafts 0,25 mm, TCI platforms, flat handle, width 6 mm, overall length 84 mm....
Medicine Products: