Navigation Links
Researchers explore connection between popular pain relievers, bladder cancer
Date:11/7/2012

(Lebanon, NH, 11/5/2012) Dartmouth researchers have found that duration of ibuprofen use was associated with a reduced risk of bladder cancer in patients in northern New England, which has a high mortality rate of this disease. In a 2012 collaborative project with the National Cancer Institute, Margaret Karagas, PhD, co-director, Cancer Epidemiology & Chemoprevention program at Norris Cotton Cancer Center, and Professor of Community and Family Medicine at the Geisel School of Medicine at Dartmouth, and Richard Waddell, D.Sc, Research Assistant Professor of Medicine at the Geisel School of Medicine, looked for connections between ibuprofen use and bladder cancer.

Bladder cancer and ibuprofen use

Karagas did an earlier study on the relationship between bladder cancer and nonsteroidal anti-inflammatory drugs (NSAIDs) usage in New Hampshire. The new study included patients in Vermont and Maine. Researchers enrolled 1,171 participants newly diagnosed with bladder cancer and 1,418 participants who did not have bladder cancer. Karagas also added a genetic component looking at thirty-nine genes related to NSAID metabolism and studied a new class of NSAIDs known as selective cyclooxygenase (COX-2) inhibitors, such as celecoxib (Celebrex). Their results were published in the International Journal of Cancer (June 2012).

Those with specific genetic traits appear to have reduced risk

The findings in the recent study suggest that "regular use of nonaspirin nonselective NSAIDs, particularly ibuprofen, may reduce bladder cancer risk, especially among regular users for 10 years or more." However, the study also notes that observed reduction in risk was specific to individuals carrying a specific allele (or variant of a gene) related to NSAID metabolism.

Findings suggest further study needed for newer prescription pain reliever

For Karagas one of the novel findings was a trend of an increased
'/>"/>

Contact: Donna Dubuc
donna.m.dubuc@hitchcock.org
603-653-3615
Dartmouth-Hitchcock Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers discover immune pathway
2. Temple researchers show targeted cancer drug may stunt hearts ability to repair itself
3. Researchers discover how underground rodent wards off cancer
4. Forum to bring together leading-edge ophthalmic researchers and investors
5. George Mason University researchers target breast cancer in 3 trials
6. IU researchers report first effective treatment of tumors arising from common genetic disease NF1
7. OHSU researchers discover potential way to repair brain damage in multiple sclerosis
8. Penn researchers find error reporting improves perceptions of safety and may reduce incidents
9. Common Antidepressants Too Risky During Pregnancy, Researchers Say
10. Mechanism found for destruction of key allergy-inducing complexes, Stanford researchers say
11. Feinstein Institute researchers discover that bean used in Chinese food could protect against sepsis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... its top dressmaking technologies, has been a leading dress supplier ... latest designs of wedding dresses and launching a site-wide promotion ... the fresh new products are designed for 2015, and they ... All the clothes from LunaDress follow up with the latest ...
(Date:1/22/2015)... 2015 VogueQueen is a seasoned and trusted ... many designers are thrilled to have it lead the wedding ... new collection of prom dresses for the global market. , ... strategic vision and he focuses on continuing the goal of ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 The federal court ... the U.S. District Court, Southern District of West Virginia has ... in that proceeding’s first bellwether trial. In an Order dated ... new trial after finding that C.R. Bard had not proven ...
(Date:1/22/2015)... For over 20 years, Dr. David Cruz of Cruz ... has treated just about every type of injury that can result ... those same twenty-plus years, the team at Doctors on Liens ... best possible doctor. With the combined breadth of experience ...
(Date:1/22/2015)... Recently, Weddingshe.com has added many trendy Champagne wedding ... revenues in the past three years. Today, the business announces ... According to the sales manager of the company, this is ... 2015. This point can be reflected on the discounted wedding ...
Breaking Medicine News(10 mins):Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2
... of Molecular, Cellular and Developmental Biology (MCDB) and faculty ... prestigious 2006 E. B. Wilson Medal, the American ... in cell biology. ,The medal is indeed ... and function of fine, hair-like cell organelles, called cilia ...
... bath in divine dew, sunshine, herbal soup, joss-stick smoke or ... ,Sitting in a room lit with homemade joss sticks ... According to the Tibetan medical code, there are a myriad ... ,The most popular cleansing rituals include river baths, dips in ...
... suffer most under global warming. Past history gives us ... Of greatest concern are the 'large infrequent disturbances' to ... effects. In a remarkable study from the Kenyan Tsavo ... Ecology, Dr Lindsey Gillson uncovers evidence for a drought ...
... children who reportedly swallowed tiny magnets that fell off ... the Consumer Product Safety Commission has// ordered a major ... made by Mattel.,Mattel is an El Segundo-based toy manufacturer. ... around 170 complaints reporting that small magnets fell out ...
... with autism and related advocacy groups are questioning the ... a strategy for laying out// treatment resources equally across ... a series of small steps intended for helping researchers ... Media Conference, Sam Yassine, father of an autistic child ...
... of Tourism of Philippines, proposes to link-up with tour ... and check-ups with rest and recreation in// the itinerary ... ,Cynthia Carrion, the assistant secretary for Sports and Wellness ... [coordinating] with the PTAA (Philippine Travel Agencies Association) and ...
Cached Medicine News:Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 2Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 3Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 4Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 5Health News:Impact of Climate Change in Africa 2
(Date:1/22/2015)... Calif. , Jan. 22, 2015  Amgen (NASDAQ: AMGN ... full year 2014 financial results on Tuesday, Jan. 27, 2015, after ... followed by a conference call with the investment community at 2 ... Robert A. Bradway , chairman and chief executive officer, and other ...
(Date:1/22/2015)... , Jan. 22, 2015 Increasing sophistication among ... consolidation of localization purchasing in 2015, says Moravia ... to a recent study by market research firm Common ... single-source solution for their translation and localization needs. "From ...
(Date:1/22/2015)... Markets ( http://www.researchandmarkets.com/research/w25xpc/allergy ) has announced the addition ... & by End User - Global Forecast to 2019" ... diagnostics market is valued at $1,228.58 million in 2014 and ... reach $2,230.72 million by 2019. Allergy diagnostics is used to ...
Breaking Medicine Technology:Amgen Announces Webcast of 2014 Fourth Quarter and Full Year Financial Results 2Moravia Sees Single-Sourcing as Key Localization Trend in 2015 2Global Allergy Diagnostics (Immunoassay Analyzer, Luminometer, Assay Kit, Consumables) Market - Forecast to 2019 2Global Allergy Diagnostics (Immunoassay Analyzer, Luminometer, Assay Kit, Consumables) Market - Forecast to 2019 3
... Robbins & Myers, Inc. (NYSE: RBN ) ... second quarter ending February 28, 2010 , before the market ... is scheduled for Wednesday, March 24, 2010 , at ... Officer, and Christopher M. Hix , Vice President and Chief ...
... March 10 CVS Caremark Corporation (NYSE: CVS ) today announced that its Board of Directors has approved a quarterly dividend of $0.0875 per share on ... ... ... ...
Cached Medicine Technology:Robbins & Myers to Release Second Quarter Fiscal 2010 Financial Results 2CVS Caremark Corporation Announces Quarterly Dividend 2
PLX30s, 30 Watt Sealed CO2 Laser System....
... Super Pulse sealed CO2 surgical lasers offer ... the experience and support services of a ... laser experience. All settings are available at ... MD Super Pulse surgical lasers are compatible ...
Ophthalmic Nd Yag Laser with excellent quality optics for clear image and good laser delivery. Compact and light-weight for portability....
A conventional blue visibility-tinted daily-wear lens, custom made for astigmats with up to -3.00 D of cylinder requiring adds of up to +2.50 D....
Medicine Products: