Navigation Links
Researchers discover strategy for predicting the immunity of vaccines
Date:11/23/2008

ell and antibody responses in their blood. There was a striking variation in these responses between individuals. Analysis of gene expression patterns in white blood cells revealed in the majority of the individuals the vaccine induced a network of genes involved in the early innate immune response against viruses.

"Using a bioinformatics approach, we were able to identify distinct gene signatures that correlated with the T cell response and the antibody response induced by the vaccine," says Pulendran. "To determine whether these gene signatures could predict immune response, we vaccinated a second group of individuals and were able to predict with up to 90 percent accuracy which of the vaccinated individuals would develop a strong T or B cell immunity to yellow fever," continues Pulendran.

Pulendran and his colleagues are now working to determine whether this approach can be used to predict the effectiveness of other vaccines, including flu vaccines. The ability to successfully predict the immunity and effectiveness of vaccines would facilitate the rapid evaluation of new and emerging vaccines, and the identification of individuals who are unlikely to be protected by a vaccine.

"This type of research is essential to answer fundamental questions that can lead to better vaccinations and prevention of disease. Yerkes, as one of only eight National Institutes of Healthdesignated national primate research centers, is uniquely positioned to carry out such diverse research," says Stuart Zola, PhD, director, Yerkes Research Center.


'/>"/>

Contact: Emily Rios
erios@emory.edu
404-727-7732
Emory University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Ability to quit smoking may depend on ADHD symptoms, Columbia researchers find
2. Researchers ID Suite of Genes in Aging Process
3. Researchers: Ban on fast food TV advertising would reverse childhood obesity trends
4. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
5. Leeds researchers reshape the future of drug discovery
6. UNC researchers find clue to stopping breast-cancer metastasis
7. U of U researchers to use patients own stem cells to treat heart failure
8. Researchers identify toehold for HIVs assault on brain
9. Researchers Tackle CLL, Diabetes and Trauma-Hemorrhage
10. Researchers Use New Method to Control Bleeding in Hemophilia
11. Stem cells with potential to regenerate injured liver tissue identified by Penn researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... May 27, 2015 One of America's ... upcoming episode of “In America” that takes a look ... is best described as an abnormal heart rhythm. Those ... beats either irregularly or much too quickly. , This ... fibrillation develops in an effort to inform viewers about ...
(Date:5/27/2015)... 27, 2015 According to research conducted ... Medical Center at Dallas some migraine patients have an ... and migraine headache apparently also have some shared risk ... obesity, people with a history of diabetes and/or smoking. ... Asians, and CTS in particular was less common in ...
(Date:5/27/2015)... (PRWEB) May 27, 2015 HomeTown Health, ... to six north Georgia cities on May 13 & ... for local physicians to meet with the group of ... 120 physicians and office staff attended. , Referred ... is designed to bring together Health Information Technology and ...
(Date:5/27/2015)... The Advanced Fertility Center of Chicago announces that ... to better serve the needs of couples in Chicagoland. ... the Northwest side of the city at 4920 North Central ... calling the Chicago office at (773) 794–1818. This is ... Chicago. The other 2 offices are in Gurnee and ...
(Date:5/26/2015)... In celebration of Parker and Sons forty years of service, ... systems with a high Season Energy Efficiency Rating (SEER) which ... SEER rating around 15-16 can be purchased for under $40/month, ... a SEER rating, it is essentially what miles per gallon ... of energy expended by the actual heating and cooling dispersed. ...
Breaking Medicine News(10 mins):Health News:Santa Rosa Orthopaedics Offers Insights into Recent Study Results Connecting Migraines with Chronic Conditions Such as Carpal Tunnel Syndrome 2Health News:Santa Rosa Orthopaedics Offers Insights into Recent Study Results Connecting Migraines with Chronic Conditions Such as Carpal Tunnel Syndrome 3Health News:Santa Rosa Orthopaedics Offers Insights into Recent Study Results Connecting Migraines with Chronic Conditions Such as Carpal Tunnel Syndrome 4Health News:HomeTown Health Leads Rural Physician Bus Tour; Brings Resources and Education to North Georgia 2Health News:HomeTown Health Leads Rural Physician Bus Tour; Brings Resources and Education to North Georgia 3Health News:The Advanced Fertility Center of Chicago Opens a New Fertility Office Location in Chicago 2Health News:Parker and Sons Recounts its Path to Success 2
... Jan. 29 Care Net , a ... to pregnant women, was drawn into the Tebow Super Bowl ... News.  Care Net President Melinda Delahoyde said the ... centers provide free services to 1.9 million people every year. ...
... , LOS ANGELES , Jan. 29 In a ... the nation,s organ donation and transplant community will vote for the best ... Seven Pounds , Return to Me , John Q ... Philadelphia Transplant Movie Night, a group of transplant recipients, living donors and ...
... public health intervention of all timeespecially in low-income countries, ... when they are sick. On Friday, January 29, speaking ... and Melinda Gates announced a new ten-year Gates Foundation ... commitment announced by Bill and Melinda Gates today will ...
... in on why listening to music seems so beneficial, , ... benefits is long: It can soothe infants and adults alike, ... beat faster or slower. "It," of course, is music. ... such suggestions for years. Just why music seems to have ...
... , ... Digestion Clinic provides natural solutions. , ... Potomac, MD (Vocus) January 29, 2010 -- Dr. David Williams is ... The site provides natural solutions that readers can act on immediately to relieve ...
... , , REDMOND, Wash. , Jan. 29 ... enlighten and transform the people attending. That is exactly what takes ... Chairman and CEO Dwayne Clark . As a national leader ... in the business of taking care of society,s "Greatest Generation." Dwayne ...
Cached Medicine News:Health News:Care Net Calls Tebow Ad Opponents' Slam of Pregnancy Centers 'Nonsensical' 2Health News:Nationwide Vote to Determine Best Organ Donation-Themed Movie 2Health News:Tune Up Your Health 2Health News:Tune Up Your Health 3Health News:Dr. David Williams Announces Launch of New Online Digestion Clinic 2Health News:Dr. David Williams Announces Launch of New Online Digestion Clinic 3Health News:Aegis Living's CEO Transforms Business As Usual One Employee At a Time 2Health News:Aegis Living's CEO Transforms Business As Usual One Employee At a Time 3
(Date:5/26/2015)... , May 26, 2015  Amgen (NASDAQ: ... from the Phase 3 OPTiM study in the ... The data published in JCO , which ... American Society of Clinical Oncology (ASCO) in 2013 and ... in patients with unresected stage IIIB, IIIC or IV ...
(Date:5/26/2015)... 2015   Generational Equity , a leading mergers ... to announce the acquisition of its client, Peaks ... Washington , by Mi-Med Supply , headquartered ... 2015. Peaks & Plains is the ... medical, incontinent, nutritional, patient care, and housekeeping equipment to ...
(Date:5/26/2015)... PORTLAND, Ore. , May 26, 2015 /PRNewswire/ ... outpatient rehabilitation business solutions, today announced the results ... rehabilitation practices perform day-to-day activities. 759 therapists, practice ... and confirmed a widespread industry need for technology ... In response to the survey findings, Clinicient published ...
Breaking Medicine Technology:Pivotal Study Results Published in Journal of Clinical Oncology Showed Talimogene Laherparepvec Improved Durable Response Rates in Patients With Metastatic Melanoma 2Pivotal Study Results Published in Journal of Clinical Oncology Showed Talimogene Laherparepvec Improved Durable Response Rates in Patients With Metastatic Melanoma 3Pivotal Study Results Published in Journal of Clinical Oncology Showed Talimogene Laherparepvec Improved Durable Response Rates in Patients With Metastatic Melanoma 4Pivotal Study Results Published in Journal of Clinical Oncology Showed Talimogene Laherparepvec Improved Durable Response Rates in Patients With Metastatic Melanoma 5Pivotal Study Results Published in Journal of Clinical Oncology Showed Talimogene Laherparepvec Improved Durable Response Rates in Patients With Metastatic Melanoma 6Pivotal Study Results Published in Journal of Clinical Oncology Showed Talimogene Laherparepvec Improved Durable Response Rates in Patients With Metastatic Melanoma 7Pivotal Study Results Published in Journal of Clinical Oncology Showed Talimogene Laherparepvec Improved Durable Response Rates in Patients With Metastatic Melanoma 8Generational Equity Announces the Acquisition of Peaks & Plains Inc. by Mi-Med Supply 2Survey: Half of Physical Therapists Underbill For Their Services 2
... NEW YORK , April 26 ... Healthy U, LLC for the Apple iPhone, is now available on ... is the first of its kind to help people live healthier ... which among other things can help them eat better, sleep better ...
... BOSTON , April 26 Although federal lawmakers have ... providers to use electronic information systems to improve patient care, thousands ... computerized ordering of medications. , ... The National Patient Safety Foundation (NPSF) has awarded a ...
Cached Medicine Technology:Heal Your 'Body & Mind' on the iPad, Too! 2Heal Your 'Body & Mind' on the iPad, Too! 3National Patient Safety Foundation Awards Grant to Research Safety of Computerized Ordering of Medications 2National Patient Safety Foundation Awards Grant to Research Safety of Computerized Ordering of Medications 3National Patient Safety Foundation Awards Grant to Research Safety of Computerized Ordering of Medications 4
36" Penrose drains...
12" Penrose drains...
Offers a more constant suction profile than three-spring evacuators, resulting in the potential for improved tissue approximation and reduced risk of hematoma....
Reliavac® 400cc kits with flat drain, Y-connector tubing...
Medicine Products: