Navigation Links
Researchers discover primary role of the olivocochlear efferent system
Date:3/29/2013

hard to conceive that some vertebrates, thousands of years ago, were submitted to stimuli similar to those delivered by speakers. So many researchers believed that the protective effects of the efferent system were an epiphenomenon not its true function."

Instead of using loud noise exposures evoking a change in hearing threshold, we used a moderate noise exposure at a level similar to those found in restaurants, conferences, malls, and also in nature (some frogs emit vocalizations at similar or higher levels) and instead of looking at thresholds, we looked for signs of cochlear neuropathy, Dr. Maison continued.

The researchers demonstrated that such moderate exposure lead to cochlear neuropathy (loss of auditory nerve fibers), which causes difficulty to hear in noisy environments.

"This is tremendously important because all of us are submitted to such acoustic environments and it takes a lot of auditory nerve fiber loss before it gets to be detected by simply measuring thresholds as it's done when preforming an audiogram," Dr. Maison said. "The second important discovery is that, in mice where the efferent system has been surgically removed, cochlear neuropathy is tremendously exacerbated. That second piece proves that the efferent system does play a very important role in protecting the ear from cochlear neuropathy and we may have found its main function."

The researchers say they are excited about this discovery because the strength of the efferent system can be recorded non-invasively in humans and a non-invasive assay to record the efferent system strength has already been developed and shows that one is able to predict vulnerability to acoustic injury (Maison and Liberman, Predicting vulnerability to acoustic injury with a noninvasive assay of olivocochlear reflex strength, Journal of Neuroscience, 20:4701-4707, 2000).

"One could envision applying this assay or a modified version of it to human populat
'/>"/>

Contact: Mary Leach
Mary_Leach@meei.harvard.edu
Massachusetts Eye and Ear Infirmary
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Researchers develop a new cell and animal model of inflammatory breast cancer
3. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
4. Researchers Find Gene Mutations That May Be a Key to Autism
5. Researchers find evidence of banned antibiotics in poultry products
6. NJ stroke researchers report advances in spatial neglect research at AAN Conference
7. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
8. Researchers Map Brain Regions Linked to Intelligence
9. Researchers ID Genes That May Determine Mental Illness
10. Researchers Develop Blood Test for Depression
11. University of Cincinnati researchers win $3.7M grant from US Department of Defense
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... December 20, 2014 It’s very easy to ... something that is put to the wayside until Christmas and ... have that travel “itch” and that burning desire to just ... families on their journey to Telluride with a no-fuss, affordable ... to and from the resort, and ensure that all accommodations ...
(Date:12/19/2014)... Silver Dollar City is picking up ... the first time ever, Silver Dollar City has a title ... 2015, listing the park’s wood coaster Outlaw Run as the ... announced this week, Silver Dollar City is named in CNN ... USA Today’s 10Best awards for “Best Public Lights Display,” and ...
(Date:12/19/2014)... 2014 The Medspa at Hendrick in ... from respected cosmetic brand Juvéderm. Voluma XC treats volume ... The Medspa at Hendrick is pleased to be able ... technology to its clients. , Voluma is the first ... to treat the mid-face and cheek area. This non-invasive ...
(Date:12/19/2014)... -- Potentially illness-causing E. coli bacteria were found on ... to a new study. Researchers checked cilantro, basil ... markets in Los Angeles and Orange counties in California, ... samples tested, 24 percent were positive for E. coli. ... researchers. Both types of bacteria can cause sometimes ...
(Date:12/19/2014)... December 19, 2014 Surviving Mesothelioma says thousands ... information indicates that these pipes can leach asbestos into drinking ... the full story on the Surviving Mesothelioma website. ... of natural asbestos deposits, decaying water mains made of asbestos ... , To protect consumers from mesothelioma , water ...
Breaking Medicine News(10 mins):Health News:Days Inn Montrose Colorado Delivers Last Minute Holiday Season Ski Getaway Accommodations 2Health News:Silver Dollar City Nets New Titles: Guinness Book of World Records, Plus CNN Travel, USA Today & Fodor’s Top Places for Christmas Lights 2Health News:Breakthrough New Injectable Dermal Filler Voluma XC Offered by The MedSpa at Hendrick 2Health News:E. Coli Germs Found on Farmers Market Herbs 2Health News:Surviving Mesothelioma Warns of Potential Mesothelioma Risk from Cement Water Pipes 2
... Childhood has shown that chidren who are overweight// at age ... starts from childhood and there are evidences to show that ... adulthood. But studies on the associations of body size with ... present study was undertaken to determine the association between obesity ...
... people may cause similar kind of brain damage as happens// ... in the age group of 17 to 26yrs may be ... non-addicted counterparts, said a study done by scientists of University ... equivalent to that happens in the early stage of Alzheimer’s ...
... et al., "Expression profiles and functional analyses of Wnt-related genes// ... of The American Journal of Pathology. The article revolves around ... disruption can lead to cancer in various organs. But current ... joint disease. ,At present a through analysis of the ...
... JAMA says that infective endocarditis is largely due to staphylococcal ... is an infection that affects the inner linings of the ... valves, the connective tissues surrounding the valves, and the inner ... also affect the linings of the arteries coming out of ...
... found that older women suffering from chronic cytomegalovirus// (CMV)(a lifelong ... more than triple the risk of being frail than those ... the Journal of the American Geriatrics Society. This is the ... been shown. CMV is a common lifelong infection but it ...
... Based on findings of a recent study researchers say that ... in milk, cheese, yogurt and fortified orange juice can actually ... (PMS) symptoms. ,Studies in the past have shown that ... studies suggest that when calcium is combined with enough vitamin ...
Cached Medicine News:Health News:Arthritis and the Wnt Factor 2
(Date:12/19/2014)... INDIANAPOLIS and LYON, France ... (NYSE: LLY ) and Adocia (Euronext Paris: ... focused on developing an ultra-rapid insulin, known as BioChaperone ... type 2 diabetes. BioChaperone Lispro relies on Adocia,s proprietary ... Lilly and Adocia will develop BioChaperone Lispro ...
(Date:12/17/2014)... STUTTGART , Alemania, December 17, 2014 ... del año anterior, con un alto nivel de gasto ... pasado año fiscal 2013/14 (finalizado el 30 de septiembre ... por ciento a 4.287 millones de euros (año anterior: ... de la moneda desfavorables. Las ganancias (EBIT) crecieron un ...
(Date:12/17/2014)... , Dec. 17, 2014  Northstar Global ... Depository Trust Company (DTC) has made their final ... Chill on the Company,s stock effective December 15, ... common stock for depository and book entry transfer ... Company is now once again fully "DTC Eligible", ...
Breaking Medicine Technology:Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 2Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 3ZEISS confirma su posición en un entorno difícil 2Northstar announces that the DTC chill on MDIN has been officially lifted 2Northstar announces that the DTC chill on MDIN has been officially lifted 3
... 8, 2011 INNOPHARMA LLC announced ... for levetiracetam injection (the generic equivalent of Keppra® injection from ... injectable drug, INNOPHARMA entered into a license agreement with X-GEN ... About INNOPHARMA: INNOPHARMA ...
... 8, 2011 Echo Therapeutics, Inc. (Nasdaq: ... as a non-invasive, wireless, transdermal continuous glucose monitoring (tCGM) ... delivery, today announced the receipt of notices of issuance ... notices of registration for the trademarks PRELUDE and SYMPHONY. ...
Cached Medicine Technology:Echo Therapeutics Announces Multiple Patents and Trademark Grants 2Echo Therapeutics Announces Multiple Patents and Trademark Grants 3
PRINCIPLE: The QC-SLIDES™ are specifically designed microscope slides intended to be part of the quality control program to monitor microbiological stains and staining techniques....
... KWIK-QC Slides have a positive and ... sample inoculation. With these slides, perform QC ... ,Laboratories enhance their education and training programs ... and interpretation, all on one slide! KWIK-QC ...
Each slide contains Giardia lamblia trophozoites applied as a mono-layer to the side....
Each slide contains a high yield of concentrated C. parvum oocysts within the positive control well. A negative control well is also included....
Medicine Products: