Navigation Links
Researchers discover method to decrease harmful cyanogens and increase protein levels in key crop
Date:8/2/2011

221.10.254.64

ST. LOUIS, MO August 2, 2011 Researchers working at The Donald Danforth Plant Science Center have made an another advancement in their efforts to improve the root crop cassava which is a major source of calories to 700 million people worldwide, primarily living in the developing world. A study conducted by Dr. Narayanan N. Narayanan and Dr. Uzoma Ihemere, research scientists working in the lab of Dr. Richard T. Sayre, have developed an approach that not only accelerates the reduction of cyanogen during food processing, resulting in a safer food product, but also lead to increased root protein levels and enhanced nutritional value. The results of this research are published in the recent article, "Overexpression of Hydroxynitrile Lyase in Cassava Roots Elevates Protein and Free Amino Acids while Reducing Residual Cyanogen Levels," in the PloS One journal.

Cassava has many properties that make it an important food source across much of Africa and Asia. It grows well in poor soils with little rainfall, but it also has many limitations; both leaves and roots contain potentially toxic levels of cyanogenic glucosides and although calorie dense, the starchy, tuberous roots provide the lowest sources of dietary protein among the major staple food crops; less than 30% of the minimum daily requirement.

Insufficient protein intake often leads to protein energy malnutrition (PEM), which can lead to permanent physical and mental disabilities. Cassava has the lowest protein to energy ratio (P:E) of any staple food, making resource-poor populations that rely on cassava as their major source of calories at high risk of PEM. According to the World Health Organization, PEM is by far the most lethal form of malnutrition, affecting one in four children in Africa.

Hydroxynitrile Lyase (HNL) is a natural cassava protein that contains 50% essential amino acids and is found in the leaves of the plant. It can be eaten by humans with no allergic side effects. Narayanan and his colleagues showed that transgenic roots expressing HNL had a 53-74% reduction in root cyanogen levels, and resulted in a nutritionally enhanced cassava that contained three times as much protein and twice as much total amino acids when compared with wild type. They also proved that over-expression of HNL reduced the time required to process and remove life threatening cyanogens in the tuberous roots from days to minutes. Significantly, HNL is heat stable and will tolerate cooking for 15 minutes which is helpful in variety of food preparation methods.

"This breakthrough demonstrates that it is possible to use genetic modification to deliver enhanced cassava with decreased cyanogenic content as well as increased protein and essential amino acids that will directly benefit children and at-risk populations," said Narayanan.


'/>"/>

Contact: Melanie Bernds
mbernds@danforthcenter.org
314-587-1647
Donald Danforth Plant Science Center
Source:Eurekalert  

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers discover method to decrease harmful cyanogens and increase protein levels in key crop 
(Date:2/26/2017)... ... 26, 2017 , ... IndustryArchive.Org . is announcing a new way for ... will now only pay for B.A.N.T. quality sales leads based on the Sellers decision ... the new reality that B2B buyers are controlling the sales process via the Internet ...
(Date:2/26/2017)... Miami, Florida (PRWEB) , ... February 26, 2017 ... ... disease (PD) patients after receiving cognitive rehabilitation, according to a study released today ... already known that cognitive rehabilitation programs are proven to be effective in improving ...
(Date:2/24/2017)... ... February 24, 2017 , ... HealthPostures, ... Go. Core benefits and advantages built into the home office sit stand solution ... and feel. Ability to gain the benefits embedded in the TaskMate Go are ...
(Date:2/24/2017)... ... 24, 2017 , ... WHAT: , The New Jersey Tech ... well as advocacy for the state and region‘s technology businesses, hosted their 2017 ... Council's Innovation Forecast event highlights innovation throughout the region from small to large ...
(Date:2/24/2017)... ... February 24, 2017 , ... The Smart Machine Age is here, and ... that 47 percent of all jobs in the United States may be taken over ... day of the aggressive know-it-all who steamrolls over colleagues is drawing to a close. ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... 23, 2017  Directors from Pharma To Market Pty Ltd and ... forces, resulting in the founding of Pharma To Market Pte Ltd, ... Market are pleased to announce their expansion into Asia ... Singapore . The company are delighted to appoint Joelle ... Singapore based entity. Joelle brings with her ...
(Date:2/24/2017)... 24, 2017  Xynomic Pharmaceuticals, Inc., an oncology drug ... has acquired exclusive worldwide rights to develop, manufacture ... inhibitor targeting hematological and solid tumors. ... and 2 clinical trials of Abexinostat in US, ... already been completed, demonstrating that Abexinostat is clinically ...
(Date:2/23/2017)... Südkorea, 23. Februar 2017 LG Innotek hat ... vorgestellt. Die Sterilisationsleistung beträgt das 1,5-fache des 45-mW-Moduls der ... im Bereich zwischen 200 und 280 nm und eignet sich ... indem es ihre DNA zerstört. Das Produkt von LG ... ...
Breaking Medicine Technology: