Navigation Links
Researchers discover common cell wall component in Chlamydia bacteria
Date:12/11/2013

Researchers studying Chlamydia trachomatis bacteria, which cause the sexually transmitted infection chlamydia as well as infectious blindness, have confirmed that the bacteria containand, in fact, cannot function withoutthe common molecule peptidoglycan, a structural component found in the cell wall of many bacteria. This finding puts an end to years of uncertainty about whether Chlamydia bacteria, like almost all bacterial species, rely on peptidoglycan to reproduce and to maintain their shape and structure. In addition, the novel method the investigators used may be adapted to further examine the molecule's role in the structure and function of other bacteria.

Scientists had long known that Chlamydia infections could be treated with antibiotics that block peptidoglycan synthesis, but previous attempts to detect the molecule in the bacteria were unsuccessfulan apparent paradox known as the "chlamydial anomaly." In the new study, researchers at the Uniformed Services University of the Health Sciences and Indiana University modified certain amino acids, the building blocks of peptidoglycan, by labeling them with chemicals that can be detected using a fluorescent dye. When fed to growing Chlamydia bacteria, the modified amino acids glowed as they were incorporated into peptidoglycan, indicating the regions where the molecule was being produced and confirming its presence.

In addition to helping resolve the chlamydial anomaly, this method can be used to examine other aspects of peptidoglycan production in Chlamydia bacteria. This technique may also be adapted to enhance visualization of peptidoglycan in other bacterial species, the study authors write.

The work, published Dec. 11 in Nature, was supported by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of General Medical Sciences, both of the National Institutes of Health.


'/>"/>

Contact: Nalini Padmanabhan
padmanabhannm@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert  

Page: 1

Related medicine news :

1. Researchers at Mount Sinai Say a New Strain of Bird Flu Packs a Punch Even After It Becomes Resistant to Drugs
2. OHSU researchers develop new drug approach that could lead to cures for wide range of diseases
3. Keep on exercising, researchers advise older breast cancer survivors
4. CU researchers may have discovered a plan to disable Menieres disease
5. Norwegian brain researchers share Horwitz prize
6. RI researchers validate tool for pain assessment in patients following cardiac surgery
7. University of California Researchers Validate Automated Breast Density Software
8. UAlberta researchers uncover why combination drug treatment ineffective in cancer clinical trials
9. Researchers identify fundamental differences between human cancers and genetically engineered mouse models of cancer
10. UEA researchers receive share of £1.26 million to reduce animal experimentation for drug development
11. Prostate cancer stem cells are a moving target, UCLA researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers discover common cell wall component in Chlamydia bacteria
(Date:7/21/2017)... ... July 21, 2017 , ... The Bryant Agency, a ... and business owners in the Dalton region, is working in conjunction with the ... assault and physical abuse. , The GreenHouse is headquartered in Dalton and provides ...
(Date:7/21/2017)... ... July 21, 2017 , ... ... financial planning services to communities in the greater Birmingham area, is joining the ... to underprivileged young people in the region. , The Chris Hammond Youth Foundation ...
(Date:7/21/2017)... Norwalk, Connecticut (PRWEB) , ... July 21, 2017 , ... ... data from HealthCareMandA.com . The number of hospital acquisitions rose to 23 in ... quarter of 2017, and up 15% from the 20 announced deals in the year-ago ...
(Date:7/21/2017)... Basking Ridge, NJ (PRWEB) , ... July 21, ... ... Hills (VNA) has received a $5,000 grant from the C. R. ... Adult Day Center at Somerset Hills , a service available through the ...
(Date:7/21/2017)... Fresno, CA (PRWEB) , ... July 21, 2017 , ... ... Ms. “Tu” Tuantu Doan Vu, PA-C. Beginning July 17, 2017, Ms. Vu will join ... than 27 years of experience in dermatology, skin cancer , and more. She ...
Breaking Medicine News(10 mins):
(Date:7/17/2017)... ORLANDO, Fla. , July 17, 2017  MedX ... - branded medical testing, strengthening and rehabilitation equipment, today ... Back Machine Program. MedX is considered the gold standard ... world leader in specialized medical strengthening equipment. ... into a lease with the physician or practice who ...
(Date:7/13/2017)... 2017  Centurion Medical Products, a leader in medical product innovation ... impaction removal device for hospice patient care. ... Centurion Medical Products ... Patient pain management and emotional comfort are part of ... patient pain while preventing unneeded emergency department admission due to severe ...
(Date:7/12/2017)... , July 12, 2017  Eli Lilly and Company ... agreement with generic companies to resolve pending patent litigation in ... Virginia regarding the Cialis ® (tadalafil) ... on April 26, 2020. As part of the agreement, Cialis ... September 27, 2018. "The unit dose patent for ...
Breaking Medicine Technology: