Navigation Links
Researchers discover common cell wall component in Chlamydia bacteria
Date:12/11/2013

Researchers studying Chlamydia trachomatis bacteria, which cause the sexually transmitted infection chlamydia as well as infectious blindness, have confirmed that the bacteria containand, in fact, cannot function withoutthe common molecule peptidoglycan, a structural component found in the cell wall of many bacteria. This finding puts an end to years of uncertainty about whether Chlamydia bacteria, like almost all bacterial species, rely on peptidoglycan to reproduce and to maintain their shape and structure. In addition, the novel method the investigators used may be adapted to further examine the molecule's role in the structure and function of other bacteria.

Scientists had long known that Chlamydia infections could be treated with antibiotics that block peptidoglycan synthesis, but previous attempts to detect the molecule in the bacteria were unsuccessfulan apparent paradox known as the "chlamydial anomaly." In the new study, researchers at the Uniformed Services University of the Health Sciences and Indiana University modified certain amino acids, the building blocks of peptidoglycan, by labeling them with chemicals that can be detected using a fluorescent dye. When fed to growing Chlamydia bacteria, the modified amino acids glowed as they were incorporated into peptidoglycan, indicating the regions where the molecule was being produced and confirming its presence.

In addition to helping resolve the chlamydial anomaly, this method can be used to examine other aspects of peptidoglycan production in Chlamydia bacteria. This technique may also be adapted to enhance visualization of peptidoglycan in other bacterial species, the study authors write.

The work, published Dec. 11 in Nature, was supported by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of General Medical Sciences, both of the National Institutes of Health.


'/>"/>

Contact: Nalini Padmanabhan
padmanabhannm@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert  

Page: 1

Related medicine news :

1. Researchers at Mount Sinai Say a New Strain of Bird Flu Packs a Punch Even After It Becomes Resistant to Drugs
2. OHSU researchers develop new drug approach that could lead to cures for wide range of diseases
3. Keep on exercising, researchers advise older breast cancer survivors
4. CU researchers may have discovered a plan to disable Menieres disease
5. Norwegian brain researchers share Horwitz prize
6. RI researchers validate tool for pain assessment in patients following cardiac surgery
7. University of California Researchers Validate Automated Breast Density Software
8. UAlberta researchers uncover why combination drug treatment ineffective in cancer clinical trials
9. Researchers identify fundamental differences between human cancers and genetically engineered mouse models of cancer
10. UEA researchers receive share of £1.26 million to reduce animal experimentation for drug development
11. Prostate cancer stem cells are a moving target, UCLA researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers discover common cell wall component in Chlamydia bacteria
(Date:10/13/2017)... IL (PRWEB) , ... October 13, 2017 , ... ... which established the certification process to promote standards of excellence for the field ... Symposium, scheduled for March 22 – 25, 2018 in Orlando, Florida at the ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... , ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to ... unique items from across the nation, this holiday-themed event will raise funds and awareness ... VNA. The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... most popular and least understood books in the Holy Scriptures, Revelation. The Book of ... baffled scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “The Journey: ... faced every danger possible to save lost souls in the Philippines. “The Journey: From ... Carole is a dedicated teacher of the Bible. She has taught all ages and ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... --  Montrium , an industry leader in powerful ... Trial Master Files & Inspection Readiness Conference ( ... Services has selected eTMF Connect to ... a leading European contract research organization (CRO), will ... enable greater collaboration with sponsors, improve compliance and ...
(Date:9/22/2017)... SAN DIEGO , Sept. 22, 2017 ... ll medical device is now successfully helping those with ... Union. Fibromyalgia diagnosed Amanda in ... getting dressed and washing my hair, experiencing no sleep ... body in painful spasm… I cannot recommend [the AVACEN ...
(Date:9/18/2017)... 2017 EpiVax, Inc. ("EpiVax") a ... immune engineering, today announced a new NIH-funded ... ... and presents a challenge for traditional flu ... be effective. Using state-of-the-art bioinformatics and molecular modeling methods, ...
Breaking Medicine Technology: