Navigation Links
Researchers developing bioadhesive gel to protect women from HIV and HSV infections
Date:7/24/2012

MENLO PARK, Calif.July 24, 2012A new grant from the National Institute of Allergy and Infectious Diseases (NIAID) will support the development of a topical microbicide gel for drug delivery. The innovative gel formulation will be a combination therapy against human immunodeficiency virus (HIV) and herpes simplex virus type 2 (HSV-2) infections in women.

Every day, more than 3,000 women around the world are newly infected with HIV, and it is the leading cause of death in sub-Saharan Africa. Of the 33.3 million people living with HIV/AIDS across the world, 22.5 million are in Africa. HSV-2 is a global epidemic and affects up to 80 percent of the female population in Africa.

As part of the grant, SRI International researchers will develop and test a prototype bioadhesive formulation for sustained delivery of the antiviral drugs tenofovir and acyclovir to the vaginal surface. Because chronic HSV-2 infections have been shown to speed the progression of immunodeficiency disease, researchers are focused on developing a microbicide that prevents both HIV and HSV-2 infections.

"The inexpensive and easy-to-use combination therapy in development could help contain the spread of HIV and HSV, and possibly other sexually transmitted diseases," said Gita Shankar, Ph.D., director of Formulations R&D, SRI Biosciences. "One of the strongest benefits of a topical gel formula is that it can offer protection when options such as condoms are unavailable or unacceptable."

The awarded grant is for two years with a possible extension of three additional years. Development work will focus on creating a combination therapy that will limit the risk of drug resistance, while providing women with safe and sustained drug delivery. The novel product will be based on a patented bioadhesive polymeric platform developed at SRI.

This research will be supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Heal
'/>"/>

Contact: Dina Basin
dina.basin@sri.com
650-859-3845
SRI International
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Researchers develop a new cell and animal model of inflammatory breast cancer
3. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
4. Researchers Find Gene Mutations That May Be a Key to Autism
5. Researchers find evidence of banned antibiotics in poultry products
6. NJ stroke researchers report advances in spatial neglect research at AAN Conference
7. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
8. Researchers Map Brain Regions Linked to Intelligence
9. Researchers ID Genes That May Determine Mental Illness
10. Researchers Develop Blood Test for Depression
11. University of Cincinnati researchers win $3.7M grant from US Department of Defense
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... May 20, 2013 yurbuds®, maker of ... out, today announced the launch of its new Signature ... Series-Pete Jacobs, with more signature athletes to come. Created ... Signature Series ITE 100 is the perfect training partner ... ITE 100 features reflective, tangle-resistant Kevlar cords, premium sound ...
(Date:5/20/2013)... The judge overseeing pretrial proceedings in the federal ... female lawyers to be included in a plaintiffs’ leadership ... acknowledges the judge’s request, noting that its lawyers ... on Mirena side effects and how to file a ... of some female lawyers to the committee. This followed ...
(Date:5/20/2013)... WINSTON-SALEM, N.C. May 20, 2013 Nearly 20 ... in the U.S. are refused for transplant due to ... the kidney,s filtering units to the organ going too ... of being discarded, these organs could be "recycled" to ... Researchers at Wake Forest Baptist Medical Center and colleagues, ...
(Date:5/20/2013)... Amsterdam, NL, 20 May 2013 While Huntington,s ... community anticipates that new disease-modifying therapies in development ... success of HD research depends upon the identification ... and evaluate therapies, and these biomarkers may eventually ... Biomarkers could be especially helpful to monitor changes ...
(Date:5/20/2013)... Dorland Health, a division of ... annual Case In Point Platinum Awards, recognizing outstanding ... the system is patient- and family-centric, safe and ... creative work across the healthcare system that is ... of care through effective care coordination across the ...
Breaking Medicine News(10 mins):Health News:yurbuds Expands Best-Selling Lines with Innovative New Products 2Health News:Mirena IUD Lawsuit Update: Judge Calls for More Input from Female Lawyers, Notes Rottenstein Law Group LLP 2Health News:Study suggests new source of kidneys for transplant 2Health News:Leading researchers report on the elusive search for biomarkers in Huntington's disease 2Health News:Leading researchers report on the elusive search for biomarkers in Huntington's disease 3Health News:Dorland Health Announces the 2013 Case In Point Platinum Awards Winners 2
... York, NY July 12, 2009) Researchers at ... compound called NIC5-15, might be a safe and effective ... to moderate Alzheimer,s disease. The two investigators, Giulio Maria ... Phase IIA preliminary clinical findings at the Alzheimer,s Association ...
... ... for Sports Medicine ,s (AOSSM) Annual Meeting in Keystone, Colorado, (July 9-12) details the benefits ... age of 14. , ... CO (Vocus) July 12, 2009 -- More and more children are participating and getting hurt ...
... strategies should help in staying calm and moving on ... for the stress level, as many in the midst of ... not surprisingly, nearly half of the 1,791 adults polled for ... that their stress had increased in the past year. As ...
... Ill., July 11, 2009 The Natural Orifice ... joint effort of the American Society for Gastrointestinal ... and Endoscopic Surgeons (SAGES), today announced Olympus, continuing ... invasive transdisciplinary therapy known as Natural Orifice Translumenal ...
... , ROCHESTER, Minn., July 11 A new Mayo ... neurodegenerative disorders in the future. The study will be ... Disease on July 11 in Vienna. , ... framework for MRI-based differential diagnosis of three common neurodegenerative ...
... ... other North American physicians as a 2009 American Orthopaedic Society for Sports Medicine ... ... Cleveland Clinic Foundation, Director of Operating Room Management, will join three other North American ...
Cached Medicine News:Health News:Mount Sinai researchers find new Alzheimer's disease treatment promising 2Health News:Risks of Delaying ACL Reconstruction in Young Athletes May Be Too High, Study Shows 2Health News:Risks of Delaying ACL Reconstruction in Young Athletes May Be Too High, Study Shows 3Health News:How to De-Stress a Recession-Riddled Life 2Health News:How to De-Stress a Recession-Riddled Life 3Health News:NOSCAR increases NOTES research with Olympus Medical Systems Corporation grant 2Health News:Mayo Clinic Study Using Structural MRI May Help Accurately Diagnose Dementia Patients 2Health News:Renowned, Cleveland Clinic Foundation, Orthopaedic Sports Medicine Surgeon, John Bergfeld, MD, Inducted into Sports Medicine Hall of Fame 2
(Date:5/20/2013)... , May 20, 2013 Sequent Medical, ... for the SL ("Single Layer") family of WEB ® ... release of these new models in select neurovascular centers ... and superior navigability that will enable physicians to treat ... The SL configurations are made possible by ...
(Date:5/20/2013)... ATLANTA , May 20, 2013  Atlantic ... developed and is commercializing a unique technology to ... founder and President, Anthony Soscia ... the Atlanta Business Chronicle ,s Health-Care Heroes ... Atlanta Business Chronicle to honor individuals and ...
(Date:5/20/2013)... 20, 2013 Enrollment of patients with Type ... dose-finding clinical trial of product candidate NewMet ™, ... for Type 2 diabetes. Elcelyx expects to complete enrollment ... June. Results of the trial,s primary endpoint of change ... and the read-out for long-term glucose lowering and weight ...
Breaking Medicine Technology:Sequent Medical, Inc. Launches New SL Family of WEB Aneurysm Embolization Devices 2Atlantic Pharmaceuticals President Named Health Care Hero Finalist in Atlanta Business Chronicle for Drug Abuse Deterrent Technology 2Elcelyx Therapeutics Enrolling Phase 2b Trial of NewMet for Type 2 Diabetes 2Elcelyx Therapeutics Enrolling Phase 2b Trial of NewMet for Type 2 Diabetes 3Elcelyx Therapeutics Enrolling Phase 2b Trial of NewMet for Type 2 Diabetes 4
... Karyopharm Therapeutics Inc., a leader in the new field of ... nuclear transport machinery plays an integral role in the regulation of ... disease. Karyopharm is focused on the discovery and development of novel ... n uclear e xport (SINE) ...
... CLEVELAND, Nov. 3, 2010 From pill-sized cameras to radioactive ... Clinic,s Top 10 Medical Innovations for 2011 showcases new techniques, ... The list of breakthrough devices and therapies was selected ... unveiled during Cleveland Clinic,s 2010 Medical Innovation Summit. ...
Cached Medicine Technology:Karyopharm Therapeutics Inc. Closes $20 Million Series A Financing to Advance Pipeline of Novel Nuclear Transport Modulators for Cancer, Inflammation and Other Disorders 2Karyopharm Therapeutics Inc. Closes $20 Million Series A Financing to Advance Pipeline of Novel Nuclear Transport Modulators for Cancer, Inflammation and Other Disorders 3Cleveland Clinic Unveils Top 10 Medical Innovations for 2011 2Cleveland Clinic Unveils Top 10 Medical Innovations for 2011 3Cleveland Clinic Unveils Top 10 Medical Innovations for 2011 4
For the quantitative determination of aspartate aminotransferase in serum. Optimized IFCC procedure without P-5'-P. 500 IU/L at 37C linearity....
The Definitive automated slide stainer is an industry standard. The Definitive allows automated slide staining in a compact, self-contained and easy-to use package....
... is an "assembly-line worker" for routine staining ... laboratories. Programmable continuous slide stainer for routine ... slides in short time. Its large number ... continuous working principle provides a high throughput. ...
HMS 760 Robot Stainer. Version includes display....
Medicine Products: