Navigation Links
Researchers develop synthetic compound that may lead to drugs to fight pancreatic, lung cancer
Date:3/9/2011

ffective." If the compound continues to demonstrate efficacy, researchers would begin work to develop a drug with the compound's properties for further testing.

The compound appears to migrate into all tissues of studied mice, but the UT Southwestern researchers don't know yet if it will penetrate solid tumors in the animal, "which is an incredibly important step in evaluating chemicals as drug leads," Dr. White said.

"We've illuminated the dark matter of regulation of an incredibly important oncogenic survival pathway. We've found a new regulatory arm of this pathway, and we've discovered you can inhibit it pharmacologically. That's target validation. The next step is to translate that target validation into development of a medicine," he said.


'/>"/>

Contact: Debbie Bolles
debbie.bolles@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Report: International collaboration between researchers results in greater recognition
2. U of M researchers using salmonella to fight cancer
3. University of South Florida researchers find blood-brain barrier damaged by disease
4. Boston researchers create SMArt platform architecture, launch $5,000 health app competition
5. UCLA researchers use nano-Velcro technology to improve capture of circulating cancer cells
6. Aging in place preserves seniors independence, reduces care costs, MU researchers find
7. Elderly see pedestrians half as often as younger drivers, according to Ben-Gurion U. researchers
8. Researchers use human cues to improve computer user-friendliness
9. Researchers find new mechanism behind the formation and maintenance of long-term memories
10. Researchers pinpoint genetic pathways involved in breast cancer
11. Penn researchers find new role for cancer protein p53
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... Steven Reinberg HealthDay Reporter ... who have dementia and heart rhythm irregularities are more likely ... has found. In fact, the study of more than ... 80 percent more likely to get a pacemaker than those ... this study is why folks with dementia are so much ...
(Date:7/28/2014)... 2014 The Oakwood Foundation celebrated a ... Songe and Associates, PC that will benefit each community ... come. , The HBWS group is among the ... $2.5 million in donations. Through their latest gift, they ... Oakwood Women’s Healthcare Classic for the next 6 years; ...
(Date:7/28/2014)... HealthDay Reporter MONDAY, July 28, 2014 ... apnea in children, but a new study confirms that the ... already overweight. The researchers said that,s a concern, because ... problems -- including, ironically, sleep apnea. But they,re not advising ... said, doctors and parents should be aware that a healthy ...
(Date:7/28/2014)... July 28, 2014 Lourdes Health System ... access and reduced wait times for veterans needing medical ... systems in the state—and the only one in Camden, ... Patient-Centered Community Care program (PC3). PC3 gives veterans access ... hospital cannot provide services due to lack of available ...
(Date:7/28/2014)... NJ (PRWEB) July 28, 2014 ... representing the majority of professionals engaged in the ... of the Transplantation and Immunology Research Network ... transplantation and immunology research. As modern organ transplantation ... a network that could provide more opportunities for ...
Breaking Medicine News(10 mins):Health News:Pacemakers Common for Those With Dementia and Irregular Heartbeats 2Health News:Pacemakers Common for Those With Dementia and Irregular Heartbeats 3Health News:Tonsillectomy for Sleep Apnea May Trigger Weight Gain 2Health News:Tonsillectomy for Sleep Apnea May Trigger Weight Gain 3Health News:Lourdes Expands Military Partnership with Veterans 2Health News:Lourdes Expands Military Partnership with Veterans 3Health News:American Society of Transplantation (AST) Launches Transplantation and Immunology Research Network (TIRN); Aims to Expand Research Collaboration & Funding 2Health News:American Society of Transplantation (AST) Launches Transplantation and Immunology Research Network (TIRN); Aims to Expand Research Collaboration & Funding 3
... Canadian scientists has revealed that vaccines that contain ... ,McGill University Health Center scientists examined patterns between ... and reported their findings in the journal Pediatrics. ... were actually higher in children given shots after ...
... India Institute of Medical Sciences remained crippled today as ... the move to sack its Director P Venugopal//. ... since last evening as resident doctors and faculty of ... headed by Union Health Minister A Ramadoss recommended the ...
... ,The meeting of provincial health ministers to approve a ... the need for financial// help of the federal government ... ,The meeting in Fredericton was planned to be conducted ... reluctant to give any more than what was agreed ...
... infertility and needing cancer therapy, it was difficult to ... removed from their normal environment//. ,But a ... a new technology (i.e.) a three-dimensional culture system that ... helped maintain a normal connection between follicle and egg ...
... it was found that teenagers who were taking cannabis on ... in their life. ,Teenagers turn in to heroin ... that they derive by taking these drugs. Cannabis is ... person to get exposed to other hard drugs. Adolescents become ...
... – involved in tumor-suppression or cell-proliferation-suppressing function resulted in ... blood sugar// regulation - researchers at the University of ... menin gene (Men1) mutation can lead to a genetic ... this discovery also has implications for diabetes treatment. ...
Cached Medicine News:Health News:Clement Urged to Plot a National Pharmaceutical Strategy 2Health News:A three-dimensional Culture System ensures Female Fertility 2Health News:Menin Gene Mutation made Insulin Secreting Cells to Proliferate 2
(Date:7/28/2014)... , July 28, 2014  MedSpring Urgent Care, an ... at 517 S. Lamar Blvd., Austin, TX ... is located on the southeast corner of Barton Springs Rd. ... 9 a.m. - 9 p.m. daily, including weekends and holidays. ... Central Austin , Anderson Mill , ...
(Date:7/28/2014)... 28 luglio 2014 ResMed (NYSE: ... per la cura dei disturbi respiratori del sonno (SDB) ... un,ingiunzione permanente in Germania contro il produttore Taiwanese di ... vendita di apparecchiature da indossare in testa, che violano ... maschere 220. La sentenza della Corte Regionale Distrettuale di ...
(Date:7/28/2014)... 2014   Cardioxyl Pharmaceuticals, Inc. announced today ... CXL-1427, a novel potential treatment for acute decompensated heart ... company has now initiated dosing of hospitalized patients with ... designed to further evaluate the drug,s safety and tolerability ... Phase I clinical trial evaluated the safety and tolerability ...
Breaking Medicine Technology:MedSpring Urgent Care opens Barton Springs walk-in clinic in Austin, TX 2ResMed riceve un'ingiunzione permanente contro APEX in Germania, continua a far valere i propri diritti per i brevetti in Europa 2Cardioxyl Pharmaceuticals Successfully Completes First Clinical Trial For Heart Failure Drug CXL-1427 2
... , THE WOODLANDS, Texas , Jan. 28 ... treatment and research network, will announce its operating results for the ... Feb. 25, 2010 . , A conference call and simultaneous webcast ... following a distribution of the earnings release. Additional information will be ...
... , TORONTO , Jan. 28 ... appointment of Patricia Archambault as vice president, healthcare ... overseeing key client relationships and healthcare team activities in the ... The vice president, healthcare, role is new for the ...
Cached Medicine Technology:US Oncology to Report 2009 Fourth Quarter and Year End Operating Results 2MS&L Appoints Patricia Archambault as Vice President, Healthcare in Montreal 2MS&L Appoints Patricia Archambault as Vice President, Healthcare in Montreal 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: