Navigation Links
Researchers develop magnetic molecular machines to deliver drugs to unhealthy cells
Date:8/10/2010

nanoparticles is of interest for its potential applications in magnetic resonance imaging, as addition of the magnetic core may make it useful as a contrast agent."

For this study, nanoparticles carrying the anti-cancer drug doxorubicin were introduced to and endocytosed by breast cancer cells. When the cancer cells containing the nanoparticles were then exposed to an oscillating magnetic field, cell death occurred.

"The novel magnetic-core silica nanoparticles are effective in activating nanovalves which release anti-cancer drugs when they are exposed to an oscillating magnetic field," Zink said.

The magnetic-field oscillation causes the zinc-doped iron oxide nanocrystals to heat. This increased heat causes the molecular machines to activate, and the doxorubicin in the pores is delivered into the cells.

"Magnetic nanocrystals are important in biomedical applications because they can be used for both therapeutics and imaging," said Cheon, director of the National Creative Research Initiative Center for Evolutionary Nanoparticles and the H.G. Underwood Professor of Chemistry and division head of the Nano-Medical National Core Research Center at Yonsei University.

"The ability to deliver anti-cancer drugs only to the cancer cells without affecting healthy cells is of key importance," added Cheon who is also a visiting professor at UCLA's CNSI.

Experiments for the research project were performed by UCLA graduate students Courtney Thomas and Daniel Ferris and Yonsei University graduate students Je-Hyun Lee and Eunsook Kim, who are part of the research group of professor Jeon-Soo Shin. The research team also involved Fraser Stoddard, a professor of chemistry at Northwestern University who began his collaboration with Zink while he was a professor of chemistry at UCLA. During his UCLA tenure, Stoddart served as Fred Kavli Chair of Nanosystems Sciences and director of the CNSI, positions now held by d
'/>"/>

Contact: Jennifer Marcus
jmarcus@cnsi.ucla.edu
310-267-4839
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. UCLA researchers discover protein that shuttles RNA into cell mitochondria
2. Help wanted: Highly cited researchers needed for high-ranking positions at research institutions
3. NIST researchers measure high infrared power levels from some green lasers
4. Mayo Clinic researchers share latest findings in CT radiation dose reduction efforts
5. Researchers develop advanced search tool to help physicians sort and retrieve vital EMR data
6. Researchers identify key enzyme in DNA repair pathway
7. Researchers study benefits of white button mushrooms
8. Use of decision-aid program increases safety for women experiencing abuse, researchers find
9. Researchers uncover biological rationale for why intensive lupus treatment works
10. OHSU Knight Cancer Institute researchers isolate importance of gene in breast cancer prognosis
11. Researchers pinpoint key stem cells for eating and sex
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... St. Joseph, Missouri (PRWEB) October 31, 2014 ... prepare for school, one Midwest optometrist feels they may ... vision problems to affect areas like concentration, school performance ... events may be too brief to identify progressive vision ... Options, St. Joseph, Mo., announces a new initiative: The ...
(Date:10/31/2014)... Oct. 31, 2014 (HealthDay News) -- Surgery for low ... where in the United States you live, a new ... experience low back pain at some point in their ... professional medical care for a spine problem," co-author Brook ... Clinical Practice, said in a college news release. ...
(Date:10/31/2014)... duration of treatment and cost, patients with early ... breast irradiation (APBI) with proton therapy versus whole ... The University of Texas MD Anderson Proton Therapy ... study based on typical patient characteristics, researchers used ... eight different types of partial and whole breast ...
(Date:10/31/2014)... lab device to give cancer researchers an unprecedented microscopic ... spread through the body, causing more than 90 percent ... tumor cells travel, the device could uncover new ways ... the university,s Whiting School of Engineering and its Institute ... new system recently in the journal Cancer Research ...
(Date:10/31/2014)... North Shore Eye Care today announced ... Island and the addition of leading ophthalmologist, William S. ... North Shore Eye Care Medical Director, Jeffrey Martin, MD. ... the Department of Ophthalmology of Winthrop-University Hospital and has ... for more than 30 years. He has been named ...
Breaking Medicine News(10 mins):Health News:New School Vision Initiative Announced by Dr. Rosenak’s Optical Options; Program Aims to Help Recognize Unseen Vision Problems That Impact School Success 2Health News:New School Vision Initiative Announced by Dr. Rosenak’s Optical Options; Program Aims to Help Recognize Unseen Vision Problems That Impact School Success 3Health News:Spinal Surgery Varies by Region in U.S.: Study 2Health News:Proton therapy shown to be less costly than some alternative radiotherapy techniques 2Health News:Proton therapy shown to be less costly than some alternative radiotherapy techniques 3Health News:Viewing cancer on the move: New device yields close-up look at metastasis 2Health News:Viewing cancer on the move: New device yields close-up look at metastasis 3Health News:William Kasper, MD Garden City Ophthalmologist, Joins Medical Staff at North Shore Eye Care 2Health News:William Kasper, MD Garden City Ophthalmologist, Joins Medical Staff at North Shore Eye Care 3
... , , SALT LAKE ... it has added 10 new sales representatives to its nationwide direct sales ... , , "We,re thrilled to be adding so ... vice president of sales and marketing at Dynatronics. "This is just ...
... , , EMERYVILLE, Calif., ... ) today announced that it will webcast an investor briefing ... Time. Speakers will review clinical data for Nexavar in breast ... 34th European Society for Medical Oncology (ESMO) Multidisciplinary Congress in ...
... , , C.S. Mott Children,s Hospital ... to have their children vaccinated against H1N1 flu, despite higher disease risk; ... ANN ARBOR, Mich., Sept. 24 With schools back in session, H1N1 ... children. A new vaccine against H1N1 flu -- strongly recommended for kids ...
... , , SAN ... company discovering and developing a new class of naturally occurring ... in Tokyo on Tuesday October 6. Jeff Watkins, CEO of ... product engine, and lead program based on naturally occurring resected ...
... N.J., Sept. 24 Marketing Technology Solutions , ... QualityHealth.com , has today filed a lawsuit alleging that ... misappropriated trade secrets and other confidential information by utilizing MTS-copyrighted online ... a health website owned and operated by MediZine. , , ...
... Singapore and Washington DC (September 24, 2009) There is clear ... cancer, according to a study published in the current issue ... The article "Lifestyle Interventions in the Prevention and Treatment ... common forms of cancer (lung, colorectal, breast, prostate and skin) ...
Cached Medicine News:Health News:Dynatronics Expands Nationwide Direct Sales Force by 25 Percent 2Health News:H1N1 Flu: Are Parents Underestimating Risk to Kids? 2Health News:H1N1 Flu: Are Parents Underestimating Risk to Kids? 3Health News:H1N1 Flu: Are Parents Underestimating Risk to Kids? 4Health News:aTyr Pharma to Present at Japan Biopharma Partnering Conference 2Health News:MediZine Named in Intellectual Property Lawsuit Filed by Marketing Technology Solutions 2
(Date:10/31/2014)... -- Though therapies are in their nascent phase, sales ... annual increase of 16.2% over the 2010-2020 period, reaching ... to Kalorama Information,s report, Stem Cell Therapeutics Markets ... have gained or are expected to gain approval from ... ever more complicated conditions, stem cell therapies hold the ...
(Date:10/30/2014)... 30, 2014 /CNW/ - Atlantic Canadians will save an ... Canada,s provinces and territories and ... of the Canadian Generic Pharmaceutical Association (CGPA), said today. ... speaking at the Atlantic Summit on Healthcare and Drug ... is being hosted by the Public Policy Forum and ...
(Date:10/30/2014)... -- Stryker Orthopaedics, the Official Joint Replacement Products of ... its debut year of the relationship at the Charles ... This marks the eleventh tournament stop along both ... has activated on-site with the "Stryker Mobility Zone" – ... importance of joint health.  The Stryker ...
Breaking Medicine Technology:Report: Stem Cell Technologies Market Growing 2Atlantic Canadians to Save $560-Million Through Unprecedented Three-Year Pan-Canadian Agreement on Generic Prescription Medicines 2Atlantic Canadians to Save $560-Million Through Unprecedented Three-Year Pan-Canadian Agreement on Generic Prescription Medicines 3Stryker Mobility Zone Makes Final Stop Of 2014 At Charles Schwab Cup Championship 2Stryker Mobility Zone Makes Final Stop Of 2014 At Charles Schwab Cup Championship 3Stryker Mobility Zone Makes Final Stop Of 2014 At Charles Schwab Cup Championship 4
... and Buffalo Grove, Ill. , May 11 Solta ... today announced that they have reached an agreement resolving lawsuits involving certain Thermage® ... , , ... U.S. District Court in Delaware by Alma Lasers seeking a declaration ...
... CrystalGenomics, Inc., a novel drug R&D company announced today that ... antibiotic candidate, CG400549, has been successfully completed in Europe . ... CG400549 is ... which is a critical enzyme in generating bacterial membrane) as it ...
Cached Medicine Technology:Solta Medical and Alma Lasers Resolve Patent Lawsuits 2Solta Medical and Alma Lasers Resolve Patent Lawsuits 3CrystalGenomics Announces Successful Completion of a Phase I SAD Clinical Trial for CG400549, its Novel Antibiotic Candidate 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: