Navigation Links
Researchers develop device that simulates gastro-intestinal tract
Date:3/31/2014

colleagues developed a laboratory device that simulates the human gut and its differing pH gradients, which play a decisive role in determining the manner, in which orally-administered medications are dissolved and then absorbed. It is now possible to fairly discriminate the formulations of a new drug and identify potential candidates for further development that are likely to be successful during clinical trials.

"By minimising human trials we would reduce the cost of development, which is then charged to patients when the drug comes to the market if the development costs are lower, then we can make new drugs more affordable," said Dr Merchant, who has research experience in industry as well as academia.

The testing device, co-developed by Dr Merchant, includes a chamber for holding a solvent medium plus a pH probe and a control unit. This monitors changes in the pH of the solvent medium in order to test the performance of a drug carrier at different levels of acidity or alkalinity, mimicking the conditions of the gastrointestinal tract. The device is particularly suitable for testing and developing dosage forms for oral delivery of drugs and can also simulate the variability between individuals.


'/>"/>

Contact: Nicola Werritt
nicola.werritt@hud.ac.uk
01-484-473-315
University of Huddersfield
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. UNC researchers show cancer chemotherapy accelerates molecular aging
2. NUS researchers developed worlds first fluorescent sensor to detect date rape drug
3. Cancer researchers find key protein link
4. Researchers: Biomarkers predict effectiveness of radiation treatments for cancer
5. Researchers issue state-of-the-state on genetic-based testing and treatment for breast cancer
6. Researchers identify impaired new learning in persons with Parkinsons disease
7. Researchers identify potential new therapeutic target for controlling high blood sugar
8. Ottawa researchers find new pathway connected to type 2 diabetes
9. Shoulder revision repair surgery not as successful 2 years later, say researchers
10. Researchers find significant increase in painkillers prescribed to US adults in the ER
11. Dartmouth researchers develop new approach to chronic lymphocytic leukemia treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers develop device that simulates gastro-intestinal tract
(Date:12/26/2014)... “Many people become overwhelmed by the thought ... and phone calls with insurance companies,” The Jones Firm ... free eBook on pedestrian and bicycle accidents . ... bicycle auto accident claims assures the injured individual that ... handling their case while they focus on recovering. ...
(Date:12/26/2014)... December 26, 2014 Parker & ... the best in heating, cooling and plumbing contractor ... hour emergency services in 2014 with regard to ... that Arizona is known for its incredibly hot ... understands the intricacies and details of a wide ...
(Date:12/25/2014)... December 26, 2014 The report ... to 2023” focuses on the current treatment landscape, ... the colorectal cancer market. Stivarga is a drug ... or rectal cancer. Boehringer Ingelheim is developing nintedanib ... treatment of refractory CRC in the US, Europe, ...
(Date:12/25/2014)... Recently, iFitDress.com, the popular online supplier of wedding dresses and ... of black one-shoulder cocktail dresses . In addition, all ... at discounted prices, up to 70% off. , ... weeks only. You know, we have thousands of frequent callers ... new items can visit our website for more details. The ...
(Date:12/25/2014)... 2014 BambooFlooringChina.com sells many bamboo products ... flooring. Today, the company announces big discounts on ... and colors. , BambooFlooringChina.com is the world’s leader in ... is valid until Jan. 20, 2015. , The bamboo ... with a natural thread. All the bamboo strips for ...
Breaking Medicine News(10 mins):Health News:Guide to Handling Pedestrian and Bicycle Accidents Released By The Jones Firm, Featured in Recent Article 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... 2010 In a major crackdown, Cambodia has forced ... country to close within the past five months. Led ... Substandard Medicines (IMC), the shops were targeted because of ... substandard and counterfeit medicines in the country. This evidence ...
... find , WEDNESDAY, April 28 (HealthDay News) -- Researchers ... disease caused by cystic fibrosis: Which comes first, infection ... to answer that question, and it looks like infection ... assistant professor of internal medicine at the University of ...
... Mouse study suggests Wnt protein might help humans with fractures, ... have found a way to significantly speed up the healing ... in humans, could mean people with fractures would be free ... huge implications," said Dr. Victor Khabie, co-director of the Orthopedic ...
... ... companies to put plans on hold in favor of protecting assets, cutting costs, and “waiting ... evidence that corporations are re-starting their strategic engines and getting back to a more typical ... Plano, ...
... ... ... to pay $520 million in civil fines, penalties and damages to settle allegations that ... its marketing and promotional practices for the blockbuster atypical antipsychotic Seroquel (U.S. ex rel. ...
... in making men masculine, research shows , WEDNESDAY, April 28 ... to testosterone in men and estrogen in women, but a ... cut. , The male hormone testosterone doesn,t work in ways ... brain during development and making males behave a certain way ...
Cached Medicine News:Health News:Cambodia takes action in fight against substandard and counterfeit medicines 2Health News:Cambodia takes action in fight against substandard and counterfeit medicines 3Health News:Pigs Yield Clues to Cystic Fibrosis-Related Lung Disease 2Health News:Scientists Find Way to Heal Broken Bones Faster 2Health News:Scientists Find Way to Heal Broken Bones Faster 3Health News:Leading Corporate Consulting Firm Says U.S. Companies are Re-focusing on Corporate Strategic Planning 2Health News:AstraZeneca Pays $520 Million to Settle Seroquel Whistleblower Claims 2Health News:AstraZeneca Pays $520 Million to Settle Seroquel Whistleblower Claims 3Health News:Typical Male Behavior Comes From Estrogen, Too 2
(Date:12/24/2014)... , Dec. 24, 2014  Diplomat Pharmacy, Inc. (NYSE: ... pharmacy, is proud to announce Jennifer Hagerman , ... Diplomat, will take office as the president of the ... induction ceremony will take place Feb. 28, 2015, at ... held at the Renaissance Center in Detroit, ...
(Date:12/24/2014)... KENNEWICK, Wash. , Dec. 23, 2014 /PRNewswire/ ... stage development company engaged primarily in the development ... and therapeutic applications, today announced that it has ... the Food and Drug Administration ("FDA") for marketing ... to Section 513(f)(2) of the U.S. Food, Drug ...
(Date:12/24/2014)... , Dec. 23, 2014  Lockton Dunning ... of Lockton Companies, announced the addition of Vice ... will join Lockton Dunning,s Pharmacy Consulting team, Excelsior ... of relevant industry experience to the position.  Most ... Market Sales at Diplomat Specialty Pharmacy, where she ...
Breaking Medicine Technology:Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 2Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 3Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3Kim Foerster Joins Lockton Companies 2
... 2012 Pernix Therapeutics Holdings, Inc. (NYSE Amex: ... the introduction of Omeclamox-Pak® , a ten-day therapy ... mg) and amoxicillin capsules (500 mg) for the treatment ... infection and duodenal ulcer disease (active or one-year history) ...
... leading events organizer UBM Live announced strong ... event for buyers and sellers of high value chemistry. ... show which takes place from February 19th to 22nd ... Major pharmaceutical, fine and specialty chemical companies that have ...
Cached Medicine Technology:Pernix Therapeutics Introduces Omeclamox-Pak®, First Product in Gastroenterology Portfolio 2Pernix Therapeutics Introduces Omeclamox-Pak®, First Product in Gastroenterology Portfolio 3Strong Booking Levels For Informex 2013 2Strong Booking Levels For Informex 2013 3
... NCP-1, was designed to maximize patient comfort ... the first ever to feature Vacuum Pump ... augmentation and reduces the "slamming" effect commonly ... treatment platform maintains patients comfort and security ...
... The Arctic Sun 2000 represents a ... The Arctic Sun System rapidly induces mild ... from therapeutic hypothermia or rapidly reduces temperature ... monitors and maintains core body temperature in ...
... Artic Sun 100 monitors and controls patient ... hypothermia associated with surgery, trauma, or other ... response to feedback provided from a patient ... ambient (room air) and 42C (107.6F) to ...
... its professional AED offeringthe G3 Pro. ... ECG color display, provides manual override ... most advanced technology available to provide ... for emergency treatment of sudden cardiac ...
Medicine Products: