Navigation Links
Researchers develop and test new molecule as a delivery vehicle to image and kill brain tumors
Date:8/3/2011

RICHMOND, Va. (Aug. 3, 2011) A single compound with dual function the ability to deliver a diagnostic and therapeutic agent may one day be used to enhance the diagnosis, imaging and treatment of brain tumors, according to findings from Virginia Commonwealth University and Virginia Tech.

Glioblastomas are the most common and aggressive brain tumor in humans, with a high rate of relapse. These tumor cells often extend beyond the well-defined tumor margins making it extremely difficult for clinicians and radiologists to visualize with current imaging techniques. Researchers have been investigating enhanced methods of attacking these cells in order to possibly delay or prevent brain tumor relapse.

In a study published in the August issue of the journal Radiology, the research team led by Panos Fatouros, Ph.D., a former professor and chair of the Division of Radiation Physics and Biology in the VCU School of Medicine who retired in 2010, demonstrated that a nanoparticle containing an MRI diagnostic agent can effectively be imaged within the brain tumor and provide radiation therapy in an animal model.

The nanoparticle filled with gadolinium, a sensitive MRI contrast agent for imaging, and coupled with radioactive lutetium 177 to deliver brachytherapy, is known as a theranostic agent a single compound capable of delivering simultaneously effective treatment and imaging. The lutetium 177 is attached to the outside of the carbon cage of the nanoparticle.

"We believe the clustering properties of this nanoplatform prolong its retention within the tumor, thereby allowing a higher radiation dose to be delivered locally," said Michael Shultz, Ph.D., a research fellow in Fatouros' lab in the Department of Radiology in the VCU School of Medicine.

"This theranostic agent could potentially provide critical data about tumor response to therapy by means of longitudinal imaging without further contrast administration," said
'/>"/>

Contact: Sathya Abraham
sbachia@vcu.edu
804-827-0890
Virginia Commonwealth University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Stomach Cancer Tumors Have Genetic Differences: Researchers
2. Traumatic brain injury: NIH-funded researchers will assess biomarkers for diagnosis and treatment
3. Researchers map minority microbes in the colon
4. Clemson University researchers are making every bite count
5. Researchers discover method to decrease harmful cyanogens and increase protein levels in key crop
6. Obesity counseling should focus on neurobehavioral processes, not personal choice, researchers say
7. Johns Hopkins researchers discover how some breast cancers alter their sensitivity to estrogen
8. Researchers aim for direct brain control of prosthetic arms
9. Researchers work to take the pressure off newborns lungs
10. Researchers capture breakthrough data on cervical spine injuries
11. To help doctors and patients, UB researchers are developing a vocabulary of pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2015)... Final Cut Pro X ... Film Studios, entitled TranSports. , “TranSports is a ... Cut Pro X,” said Christiana Austin, CEO of Pixel ... to effortlessly transition using this cool sports transition tool.” ... uniquely styled transition pack for Final Cut Pro X. ...
(Date:3/28/2015)... AZ (PRWEB) March 28, 2015 Coffee could ... also help protect you from gum disease, researchers have found. ... against gum disease. , Coffee contains antioxidants. Antioxidants fight gum ... the question researchers at Boston Univ. Henry M. Goldman School ... in the August 2014 issue of the Journal of Periodontology. ...
(Date:3/28/2015)... 2015 With more than 4,500 ... of osteoporosis, osteoarthritis and musculoskeletal diseases gathered here ... be the first time in the 17-year history ... the hot-button topic is an emerging non-pharmaceutical protocol ... scientific principles of Wolff’s law, osteogenic loading at ...
(Date:3/28/2015)... India Network visitor health insurance ... all visitors who purchase the plan before arrival in ... to purchase the insurance program as soon as travel ... for pre-existing medical conditions. Parents and grandparents traveling from ... with serious consequences to their health. Many visitors may ...
(Date:3/28/2015)... (PRWEB) March 28, 2015 One in ... according to research presented today at the American Orthopaedic ... The study examined the long term success of surgery ... “We examined survey data from 242 patients who underwent ... Justin P. Roe, MBBS, FRACS, from North Sydney Orthopaedic ...
Breaking Medicine News(10 mins):Health News:Introducing TranSports for Final Cut Pro X Users from Pixel Film Studios 2Health News:New Research Impliments Coffee May Help Fight Gum Disease and Increasing Benefits With Tylers Coffee 2Health News:Non-Drug Protocol for Building Bone Density Expected to Steal Spotlight at World Congress on Osteoporosis 2Health News:India Network Health Insurance Today Announces New Eligibility Criteria for Pre-existing Condition Health Insurance Coverage for Visitors to the United States 2Health News:India Network Health Insurance Today Announces New Eligibility Criteria for Pre-existing Condition Health Insurance Coverage for Visitors to the United States 3Health News:Young Athletes at Greater Risk for Re-Injury after ACL Surgery 2
... up to Take Control of Health, Take off Pounds to ... Gain ... a year makes!,What a difference people can make when they join together ... Washington,D.C. to join Dr. Ian Smith, Patti LaBelle, Yolanda Adams, Michael Strahan,Steve ...
... a,Washington, D.C.-based research, evaluation and consulting organization,today released ... finds,low awareness and knowledge levels about HIV/AIDS, but ... important predictors for heightened,awareness., Some key findings ... -- Only 1 percent of respondents were ...
... April 2, 2008 The Richard B. and,Lynne V. ... the Institute,s Board of Directors. As a director, she ... "We are delighted to have Mary Cheney join ... of the Cheney family,actively involved in shaping the major ...
... Oaks,Development Group announced today the company has closed on ... behind St. David Medical Center in Austin,Texas. A 29,724-square-foot ... being converted to Oaks, unique tenant-ownership model., Oaks, ... limited liability,company (L.L.C.). Tenant partners split ownership interest of ...
... Sky,One Medical, Inc. (OTC Bulletin Board: CSKI) ("China Sky ... pharmaceutical,medicinal and diagnostic products in China, today announced record,financial ... December 31,2007., Fourth Quarter 2007 Highlights ... from the fourth quarter of ...
... stalled at just 9 percent, HARTFORD, Conn., April ... need to re-examine its value proposition to break,out of ... broader market,according to a new study by Conning Research ... sold primarily by specialist agents,to a niche market of ...
Cached Medicine News:Health News:50 Million Pound Challenge Marks 1st Anniversary - What a Difference a Year Makes! 2Health News:50 Million Pound Challenge Marks 1st Anniversary - What a Difference a Year Makes! 3Health News:50 Million Pound Challenge Marks 1st Anniversary - What a Difference a Year Makes! 4Health News:Education and Media Key to Improving HIV/AIDS Awareness and Knowledge Levels in Afghanistan, New InterMedia Report Says 2Health News:Education and Media Key to Improving HIV/AIDS Awareness and Knowledge Levels in Afghanistan, New InterMedia Report Says 3Health News:Mary Cheney Joins the Cheney Cardiovascular Institute Board of Directors 2Health News:Oaks Development Group Acquires Medical Office Building in Austin, Texas 2Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 2Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 3Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 4Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 5Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 6Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 7Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 8Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 9Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 10Health News:China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2007 Results 11Health News:Conning Research: Long Term Care Insurance Industry Continues to Search for Broader Market 2
(Date:3/27/2015)... - Covalon Technologies Ltd. (the "Company" or "Covalon") (TSXV: ... issuance of an aggregate of 30,000 stock options to ... of 120,500 stock options to employees and consultants of ... years and will be exercisable for a period of ... stock option. About Covalon Covalon Technologies ...
(Date:3/27/2015)... 27, 2015 /CNW Telbec/ - Russell Williams , ... Companies (Rx&D), welcomes the 2015-2016 Quebec Budget, noting the ... on the biopharmaceutical industry. However, the association is concerned ... "We commend the government,s intent to strive for a ... to promote Quebec,s economic development ...
(Date:3/27/2015)... , March 27, 2015   Cypher ... today announced new data showing that, compared to ... technology provided highly equivalent interpretations of whether ... and did so in a fraction of the ... way for more comprehensive genetic analysis in non-invasive ...
Breaking Medicine Technology:Covalon Announces Issuance of Stock Options 2Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 2Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 3New Data at ACMG Shows Cypher's Software Can Automate Interpretation of Genetic Variants to Advance Non-invasive Prenatal Testing 2New Data at ACMG Shows Cypher's Software Can Automate Interpretation of Genetic Variants to Advance Non-invasive Prenatal Testing 3
... , , LOS ANGELES , ... that it has joined forces with New Jersey -based ... create the nation,s first IVF insurance program. The Assisted Reproduction ... financial solutions for the ever-rising costs of In Vitro Fertilization ...
... Ind. , Jan. 20 Medco Health Solutions, Inc. ... Medco Therapeutic Resource Center ® (TRC) for oncology patients headquartered ... company,s more than 850,000 patients currently living with cancer, one of ... consists of nearly 150 specialist pharmacists and more than 250 support ...
Cached Medicine Technology:New Life Agency, Inc. Joins Forces With The Diamond Institute and Walgreens Specialty Pharmacy to Introduce the Nation's First In Vitro Fertilization Insurance Program 2New Life Agency, Inc. Joins Forces With The Diamond Institute and Walgreens Specialty Pharmacy to Introduce the Nation's First In Vitro Fertilization Insurance Program 3Medco to Advance Cancer Care with Personalized and Specialized Treatment for Oncology Patients 2Medco to Advance Cancer Care with Personalized and Specialized Treatment for Oncology Patients 3Medco to Advance Cancer Care with Personalized and Specialized Treatment for Oncology Patients 4Medco to Advance Cancer Care with Personalized and Specialized Treatment for Oncology Patients 5
The PerkinElmer LS 45 Luminescence spectrometer offers versatility, reliability and ease-of-use for routine analyses in an affordable package....
Spectra 2000 Digital Spectrophotometer is designed for quantitative and qualitative analysis in visible range from 320 nm to 1020 nm....
... 400 Series Spectrophotometer ... approach to UV-VIS instrumentation. ... are incorporated into a ... in features and performance ...
... Quebec Colony Counter allows the user to quickly ... models allows for digital counting or manual counting. ... standard lens increasing magnification to 3.0X. The adjustable ... be raised or lowered. The lens also rotates ...
Medicine Products: