Navigation Links
Researchers design unique method to induce immunity to certain STDs
Date:4/30/2009

Chlamydia trachomatis is the most common bacterial agent of sexually transmitted disease, accounting for more than a million reported infections in the United States each year.

Researchers at the California NanoSystems Institute (CNSI) at UCLA and the David Geffen School of Medicine at UCLA have now designed a unique method for inducing immunity to the infection. The findings could accelerate progress toward the development of a vaccine against Chlamydia trachomatis infections, which can lead to reproductive dysfunction and profound local inflammation requiring medical attention.

Their study, which describes the first use of a novel vaccine platform that utilizes an engineered nanoparticle delivery system, appears in the April 30 edition of the peer-reviewed online journal PLoS ONE, published by the Public Library of Science, and is available at http://dx.plos.org/10.1371/journal.pone.0005409.

The research team, a partnership between UCLA immunologists and nanotechnologists, is led by Kathleen Kelly, an associate professor of pathology and laboratory medicine and a CNSI member, and Leonard H. Rome, interim director of the CNSI and a professor of biological chemistry. The team also includes Cheryl I. Champion, Valerie A. Kickhoefer, Guangchao Liu, Raymond J. Moniz, Amanda S. Freed, Lisa L. Bergmann, Dana Vaccari, Sujna Raval-Fernandes and Ann M. Chan.

The researchers were able to uncover a surprising connection between vault nanoparticles and mucosal immunity. Vaults are barrel-shaped nanoscale capsules found in the cytoplasm of all mammalian cells that can be engineered to serve as potential therapeutic delivery devices.

"The primary goal of vaccines is to generate robust cell-mediated immune responses at mucosal surfaces while reducing overall inflammation caused by infection," Kelly said. "We found that vault nanoparticle
'/>"/>

Contact: Jennifer Marcus
jmarcus@cnsi.ucla.edu
310-267-4838
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/29/2014)... retrospective study led by researchers at Brigham and ... colonoscopies for colorectal cancer screening and surveillance. The ... intervals than established guidelines support, and these recommendations ... , "Our study shows that a high percentage ... resulting in use of scarce health care resources ...
(Date:9/29/2014)... Atlantic NeuroSurgical Specialists (ANS) brain ... to celebrate their strides in their fight against brain cancer. ... at their Morristown office. , The annual BBQ has grown ... a place where patients can find love, hope and support ... and activities were enjoyed by guests, including a dunk tank ...
(Date:9/29/2014)... September 30, 2014 NAPW ... as a 2014 Professional Woman of the Year. Ms. ... in home healthcare. As the largest networking organization of ... and profession, the National Association of Professional Women is ... and nearly 300 Local Chapters. , “I love the ...
(Date:9/29/2014)... NY (PRWEB) September 30, 2014 ... B.S.N., Clinical Manager Specialist, as a 2014 Professional Woman ... prestigious distinction for leadership in clinical care. As the ... spanning virtually every industry and profession, the National Association ... with over 600,000 members and nearly 300 Local Chapters. ...
(Date:9/29/2014)... September 30, 2014 Top10BestSEOHosting.com is ... reviews about hosting products. It is headed by ... experience. The site offers research-based information and factual ... suppliers in the current market. , Top10BestSEOHosting.com ... announced that GoDaddy ( http://www.top10bestseohosting.com/go/GoDaddy.com/ ) and Bluehost ...
Breaking Medicine News(10 mins):Health News:Endoscopists recommend frequent colonoscopies, leading to its overuse 2Health News:Local Brain Tumor Foundation, ANS Center of Hope, Celebrates its Brain Cancer Patients 2Health News:National Association of Professional Women Announces Carol A. Stormer, Home Health Occupational at LHC GroupTherapist, a 2014 Professional Woman of the Year 2Health News:National Association of Professional Women Announces Sarah Shiermeister, Clinical Manager Specialist at Gentiva Health Services, a 2014 Professional Woman of the Year 2Health News:Top10BestSEOHosting.com: New Reviews for Linux Web Hosting Suppliers Available Online 2
... standard for grading, staging and "stad-ging" the chronic liver ... acquiring new knowledge on the liver pathology. Demand for ... in liver biopsy samples has been fuelled by the ... molecules on the lesions characterising the histological patterns of ...
... 31 /PRNewswire-Asia-FirstCall/ -- China Medical Technologies,Inc. (the ... leading China-based medical device,company that develops, manufactures ... that the Company has completed the previously,announced ... tumor therapy system,business (the "HIFU Business") to ...
... in Near Term Continue Trading Under the Ticker ... HAXS ) and BPO Management Services, Inc., ... focused on serving middle-market enterprises, today jointly announced ... the previously announced merger in which BPOMS will ...
... Dec. 30 Scantek Medical, Inc. (Pink ... it filed a voluntary petition in the United States ... of the United States Code. Scantek also announced ... BreastCare(TM)/BreastAlert(TM) Differential Temperature Sensor product ("BreastCare") to a medical ...
... CAMBRIDGE, Mass., Dec. 30 Biopure Corporation (Nasdaq: ... has advised the U.S. Naval Medical Research Center ("NMRC") by ... Biopure,s product Hemopure [hemoglobin glutamer - 250 (bovine)], under a ... As previously announced, the Navy had filed a protocol ...
... Dec. 30 Biopure Corporation (Nasdaq: BPUR ... The NASDAQ Stock Market stating that NASDAQ has again ... value requirements for continued listing, thereby extending the Company,s ... these rules is scheduled to resume on Monday, April ...
Cached Medicine News:Health News:A rigorous method for liver biopsy 2Health News:China Medical Technologies Announces the Completion of the Sale of its HIFU Business 2Health News:China Medical Technologies Announces the Completion of the Sale of its HIFU Business 3Health News:China Medical Technologies Announces the Completion of the Sale of its HIFU Business 4Health News:China Medical Technologies Announces the Completion of the Sale of its HIFU Business 5Health News:Healthaxis and BPO Management Services, Inc. Announce Closing of Merger 2Health News:Healthaxis and BPO Management Services, Inc. Announce Closing of Merger 3Health News:Scantek Medical Files for Chapter 11 Voluntary Bankruptcy and Receives Orders for the Sale of BreastCare(TM) 2Health News:U.S. Navy Requested Operations Trial on FDA Hold 2Health News:U.S. Navy Requested Operations Trial on FDA Hold 3Health News:Biopure Receives Extension of Time to Regain NASDAQ Listing Compliance 2
(Date:9/29/2014)... DUBLIN , Sept. 29, 2014 Research ... "Cardiac Pacemakers - Global Trends, Estimates and Forecasts, 2012-2018" ... sector is projected to reach US$5.7 billion by 2016. The ... global market share while Europe claims ... fastest growing region with a CAGR of 11.4% driving a ...
(Date:9/29/2014)... 2014  Guerbet, a pioneer in the field ... a Drug Shortage Assistance Award from the U.S. ... preventing or alleviating a drug shortage. ... to the shortage of Ethiodol (ethiodized oil) injection, ... post-approval supplements to restart manufacturing with acceptable compliance ...
(Date:9/29/2014)... , Sept. 29, 2014 Adaptive ... Next Generation Sequencing to profile the adaptive immune ... Scientific Advisory Board to provide strategic and clinical ... suite of assays in the diagnosis and monitoring ... focus of the SAB will be to support ...
Breaking Medicine Technology:Global Cardiac Pacemakers - Trends, Estimates and Forecasts to 2018 2Global Cardiac Pacemakers - Trends, Estimates and Forecasts to 2018 3Global Cardiac Pacemakers - Trends, Estimates and Forecasts to 2018 4Global Cardiac Pacemakers - Trends, Estimates and Forecasts to 2018 5Guerbet Receives FDA's Drug Shortage Assistance Award: Recognized for contributions to address a shortage of Ethiodol (ethiodized oil) injection 2Adaptive Biotechnologies Announces the Formation of a Hematologic Malignancies Scientific Advisory Board 2Adaptive Biotechnologies Announces the Formation of a Hematologic Malignancies Scientific Advisory Board 3
... Catalyst system introduces a new ... to microsurgical instrumentation. It has ... design with advanced microcomputer control ... to operate with a full ...
The Storz Premiere comes as anterior, posterior and anterior/posterior combo. The combo provides the following modes irrigation, irrigation/aspiration, vitrectomy, and illumination....
... Horizon Phacoemulsification System is ... surgical system. Lightweight and ... performance and features in ... also provides all modes ...
Compact ultrasonic phacoemulsification system....
Medicine Products: