Navigation Links
Researchers describe first 'functional HIV cure' in an infant
Date:3/3/2013

A team of researchers from Johns Hopkins Children's Center, the University of Mississippi Medical Center and the University of Massachusetts Medical School describe the first case of a so-called "functional cure" in an HIV-infected infant. The finding, the investigators say, may help pave the way to eliminating HIV infection in children.

A report on the case is scheduled for presentation at a press conference on Sunday, March 3, at the 20th Conference on Retroviruses and Opportunistic Infections (CROI) in Atlanta. Johns Hopkins Children's Center virologist Deborah Persaud, M.D., lead author on the report, and University of Massachusetts Medical School immunologist and professor Katherine Luzuriaga, M.D., headed a team of laboratory investigators. Pediatric HIV specialist Hannah Gay, M.D., associate professor of pediatrics at the University of Mississippi Medical Center provided treatment to the baby.

The infant described in the report underwent remission of HIV infection after receiving antiretroviral therapy (ART) within 30 hours of birth. The investigators say the prompt administration of antiviral treatment likely led to this infant's cure by halting the formation of hard-to-treat viral reservoirs dormant cells responsible for reigniting the infection in most HIV patients within weeks of stopping therapy.

"Prompt antiviral therapy in newborns that begins within days of exposure may help infants clear the virus and achieve long-term remission without lifelong treatment by preventing such viral hideouts from forming in the first place," Persaud says.

The researchers say they believe this is precisely what happened in the child described in the report. That infant is now deemed "functionally cured," a condition that occurs when a patient achieves and maintains long-term viral remission without lifelong treatment and standard clinical tests fail to detect HIV replication in the blood.

In contrast to a sterilizing c
'/>"/>

Contact: Lisa Larson
Lisa.larson@umassmed.edu
508-856-2689
University of Massachusetts Medical School
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Researchers develop a new cell and animal model of inflammatory breast cancer
3. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
4. Researchers Find Gene Mutations That May Be a Key to Autism
5. Researchers find evidence of banned antibiotics in poultry products
6. NJ stroke researchers report advances in spatial neglect research at AAN Conference
7. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
8. Researchers Map Brain Regions Linked to Intelligence
9. Researchers ID Genes That May Determine Mental Illness
10. Researchers Develop Blood Test for Depression
11. University of Cincinnati researchers win $3.7M grant from US Department of Defense
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... LunaDress, with its top dressmaking technologies, has been a ... is showing its latest designs of wedding dresses and launching ... company’s CEO, all the fresh new products are designed for ... to 80% off. All the clothes from LunaDress follow up ...
(Date:1/22/2015)... Woodloch Pines, an all-inclusive family resort ... as the number one best large hotel for families in ... for their annual Travelers’ Choice Awards. , TripAdvisor represents ... is home to millions of unbiased and honest traveler reviews. ...
(Date:1/22/2015)... 22, 2015 Padre Murphy's and Owner Tom ... Pro Player Health Alliance (PPHA). The PPHA's passion ... getting everyone, including NFL greats, treated for obstructive sleep apnea ... groups supporting the cause in the valley. The most recent ...
(Date:1/22/2015)... January 22, 2015 The Incredible Bulk is ... Pakulski to increase lean muscle by up to 30lbs in ... the attention of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative review. ... is a step-by-step, scientific diet formula that allows the body ...
(Date:1/22/2015)... Blue Cross and Blue Shield of Minnesota (Blue Cross) ... to “Live Fearless.” , The “Faces of Fearless” ... about how they or someone they know has faced a ... the moment. By telling these types of stories through livefearlessmn.com, ...
Breaking Medicine News(10 mins):Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2
... Information Source for ... ... http://www.searchhope.org , LOS ANGELES, March 10 Siegel+Gale, ... inviting,child-friendly web-based portal that allows sick children and their,families to easily ...
... damage that can occur in babies with congenital heart disease is ... defect results in too much blood in the lungs, more blood ... blood vessel growth is abruptly halted. , You get this burst ... we think the system gets shut down and the lungs dont ...
... Duke University Medical Center say they may have figured ... health in women than in men. , Their study, ... found that poor sleep is associated with greater psychological ... risk of heart disease and type 2 diabetes. ...
... Philadelphia is pleased to name Mary Beth Esposito-Herr, ... appointment follows an,extensive national search., (Photo: ... Hospital, Esposito-Herr served as the Vice,President of Patient ... where she also held a joint appointment in ...
... Gentiva Health,Services, Inc. (Nasdaq: GTIV ), the nation,s ... it is scheduled to,present from 8:30 a.m. to 8:55 ... Eleventh Annual Global Healthcare Conference in Miami,Florida., The ... live audio web cast,which may be accessed by visiting ...
... damage and stunted growth , , MONDAY, March 10 (HealthDay ... place pediatric patients at risk for bone damage and ... red flag concerns a signal transduction inhibitor (STI) medication ... brain tumors by short-circuiting tumor growth on the molecular ...
Cached Medicine News:Health News:Siegel+Gale Designs New 'HOPE Portal' for Childrens Hospital Los Angeles 2Health News:Siegel+Gale Designs New 'HOPE Portal' for Childrens Hospital Los Angeles 3Health News:Lung damage in babies with congenital heart disease under study 2Health News:Lung damage in babies with congenital heart disease under study 3Health News:Poor sleep more dangerous for women 2Health News:Poor sleep more dangerous for women 3Health News:The Children's Hospital of Philadelphia Appoints New Chief Nursing Officer 2Health News:Gentiva(R) Health Services to Present March 18th at Lehman Brothers Eleventh Annual Global Healthcare Conference in Miami 2Health News:Gentiva(R) Health Services to Present March 18th at Lehman Brothers Eleventh Annual Global Healthcare Conference in Miami 3Health News:New Drug for Brain Cancer Too Dangerous for Pediatric Patients 2Health News:New Drug for Brain Cancer Too Dangerous for Pediatric Patients 3
(Date:1/23/2015)... LONDON and BOSTON , January ... structure-guided drug discovery and development company, is delighted to announce ... has been awarded to Miles Congreve (Vice President ... co-founder) and Malcolm Weir (Chief Executive Officer and ...
(Date:1/22/2015)... , Jan. 22, 2015  ViewRay™, a privately held medical ... an exclusive distributor agreement with ITOCHU Corporation (Tokyo Stock ... system for the treatment of cancer in ... is the world,s first and only MRI-guided radiation therapy ...
(Date:1/22/2015)... UPI ), a medical device company that develops, manufactures ... today reported financial results for the fiscal 2015 third ... the Company,s Urgent ®  PC Neuromodulation System grew 14.5% ... compared to $3.9 million in the third quarter of ...
Breaking Medicine Technology:Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2Uroplasty Reports Record Revenue in Fiscal Third Quarter 2Uroplasty Reports Record Revenue in Fiscal Third Quarter 3Uroplasty Reports Record Revenue in Fiscal Third Quarter 4Uroplasty Reports Record Revenue in Fiscal Third Quarter 5Uroplasty Reports Record Revenue in Fiscal Third Quarter 6Uroplasty Reports Record Revenue in Fiscal Third Quarter 7Uroplasty Reports Record Revenue in Fiscal Third Quarter 8Uroplasty Reports Record Revenue in Fiscal Third Quarter 9Uroplasty Reports Record Revenue in Fiscal Third Quarter 10Uroplasty Reports Record Revenue in Fiscal Third Quarter 11Uroplasty Reports Record Revenue in Fiscal Third Quarter 12Uroplasty Reports Record Revenue in Fiscal Third Quarter 13Uroplasty Reports Record Revenue in Fiscal Third Quarter 14Uroplasty Reports Record Revenue in Fiscal Third Quarter 15Uroplasty Reports Record Revenue in Fiscal Third Quarter 16Uroplasty Reports Record Revenue in Fiscal Third Quarter 17Uroplasty Reports Record Revenue in Fiscal Third Quarter 18
... Decision Marks Delay in Potential First Treatment for Deadly Disease ... SAN ... Pulmonary Fibrosis (CPF), representing tens of thousands of patients, is responding ... which will delay potential approval of the first drug in the treatment of ...
... , May 4 A new report identifies ... "rogue" Internet pharmacies that display fake pharmacy licenses or sell prescription drugs ... , ... firms LegitScript and KnujOn provided sixteen domain name ...
Cached Medicine Technology:Coalition for Pulmonary Fibrosis Responds to News of Further Review of Pirfenidone By FDA 2Coalition for Pulmonary Fibrosis Responds to News of Further Review of Pirfenidone By FDA 3Coalition for Pulmonary Fibrosis Responds to News of Further Review of Pirfenidone By FDA 4Fake Pharmacy Licenses, No-Prescription Meds OK with Internet Companies, LegitScript Reports 2
... digital output. Three-chip color camera for brightfield, ... of high-quality color video cameras give you ... need for an efficient viewing experience. These ... of your specimen that can be easily ...
... The PM20 is a fully automatic ... high quality photomicrographs of even the most ... mind, the new PM20 system provide solution ... In addition to their automatic exposure control, ...
... The PM30 is a premium photomicrography system ... photomicrographs of even the most difficult specimens. ... new PM30 system provide solution to the ... to their automatic exposure control, the system ...
... Digital camera systems for optimum image ... mono-chrome digital camera system is specifically designed ... available. State-of-the-art electronics create bright, vibrant images ... dynamic range offered by the Leica cameras ...
Medicine Products: