Navigation Links
Researchers demonstrate that 'safe' cigarettes are as hazardous as tobacco
Date:5/12/2010

Using the same technique they developed to document the harmful effects of tobacco products, a team of researchers found that cigarettes made without tobacco or nicotine may be more carcinogenic because they actually induce more extensive DNA damage than tobacco products. The technique has been awarded U.S. patent No. 7,662,565.

The research team was led by Zbigniew Darzynkiewicz, M.D., Ph.D., professor of pathology. Their study, "DNA damage response induced by exposure of human lung adenocarcinoma cells to smoke from tobacco- and nicotine-free cigarettes," will appear in the June 1 issue of Cell Cycle (Volume 9, Issue 11).

Using laser scanning cytometry (LSC) technology to measure DNA damage response to the smoke from commercially available tobacco- and nicotine-free cigarettes, the research team expected to find the alternative products were less hazardous than regular tobacco cigarettes. However, their data suggest that exposure of cells to smoke from tobacco- and nicotine-free cigarettes leads to formation of double-strand DNA breaks (DSBs). Since DSBs are potentially carcinogenic, the data indicate that smoking tobacco- and nicotine-free cigarettes is at least as hazardous as those containing tobacco and nicotine.

The authors conclude that their methodology to assess the potential carcinogenic properties of tobacco smoke, based on measurement of DNA damage response as assessed by LSC, provides a useful addition to the battery of genotoxic tests for probing cigarette smoke hazards. Such tests, which can be applied to evaluate the effects of cigarettes and cigarette surrogate products on human health, can be important tools for regulatory agencies such as the Food and Drug Administration or, in the case of environmental smoke, by the Environmental Protection Agency.


'/>"/>

Contact: Donna E. Moriarty
donna_moriarty@nymc.edu
914-594-4536
New York Medical College
Source:Eurekalert

Page: 1

Related medicine news :

1. UCSF Researchers Identify Regulator of Human Sperm Cells
2. Researchers find broad spectrum antiviral that fights multitude of viruses
3. University of Alberta researchers develop drug interface to save lives
4. Caregivers of ICU patients are collateral damage of critical illness, say Pitt researchers
5. Researchers fight world hunger by mapping the soybean genome
6. HIV researchers solve key puzzle after 20 years of trying
7. UC Davis researchers identify brain protein for synapse development
8. UCLA cancer researchers perform complete genomic sequencing of brain cancer cell line
9. Researchers find new way to study how enzymes repair DNA damage
10. UCLA researchers image earliest signs of Alzheimers, before symptoms appear
11. Researchers find leukemia cells metabolize fat to avoid cell death
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... (PRWEB) , ... May 23, 2017 , ... Orbita’s Nathan ... Tuesday, May 23, 2017 in San Francisco. Titled Connected Health and IoT: Technology ... Home Event hosted by Parks Associates, a market research and consulting firm specializing ...
(Date:5/23/2017)... ... May 23, 2017 , ... Patients in need of a pulpotomy ... schedule an appointment, with or without a referral. Dr. Cotey is a respected dental ... patients as a healthy alternative to a tooth extraction. , When a child has ...
(Date:5/22/2017)... MO (PRWEB) , ... May 22, 2017 , ... Today, ... in Washington, MO with a public ribbon cutting ceremony. Since opening over ... offering an alternative to the emergency room. The new Our Urgent Care walk-in ...
(Date:5/22/2017)... ... May 22, 2017 , ... Faithfully following pop culture, people today are ... toned and shaped through fitness programs. It carries on to skin nourished, pampered and ... an irresistible, radiant smile. CDA has found that just like a perfectly ...
(Date:5/21/2017)... Dallas, Texas (PRWEB) , ... May 19, 2017 ... ... country, is pleased to announce the appointment of James (Jim) Vertino as Chief ... Vertino is a proven, transformational leader who drives innovation and business performance. He ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)...  The Corporate Whistleblower Center says, "We are ... clinics to call us anytime at 866-714-6466 if they ... in a substantial scheme to overbill Medicare. We ... employee of a medical equipment company if their ... medical practice groups with extra generous incentives to use, ...
(Date:5/9/2017)... -- Demonstrating its commitment to representing research- based biopharmaceutical ... Research and Manufacturers of America (PhRMA) today approved ... have to meet new research and development (R&D) ... PhRMA. "By putting in place new ... message that being a member of PhRMA means ...
(Date:5/8/2017)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO)., has completed its acquisition ... care service center company based in Chantilly, ... management programs for leading pharmaceutical manufacturers and health care ... will join Envoy Health Management, LLC , as ... firms, and other service companies. Together, WRB and EnvoyHealth ...
Breaking Medicine Technology: