Navigation Links
Researchers complete first clinical trial of Apatone for cancer treatment
Date:10/5/2007

In a significant advancement in the ongoing battle against cancer, a group of researchers from Summa Health System, IC-MedTech and other institutions have completed the first ever FDA-approved human clinical trial of Apatone. Demonstrating promising results, Apatone exploits a new strategy to selectively lower the level of compounds within tumor cells that assist in energy production and protect against chemotherapy. This non-toxic approach weakens and kills cancers in a novel way.

Apatone was discovered by Dr. Henryk Taper from the Catholic University of Leuven in Brussels, Belgium and was developed by Dr. James Jamison and Dr. Jack Summers, both of Summa Health System, and Dr. Jacques Gilloteaux, now with the American University of the Caribbean in St. Maarten. Their groundbreaking discovery found that moderate doses of Apatone eliminate many types of cancer cells, including prostate, bladder, renal and ovarian.

This strategy targets cancer cells by their inflammatory response, explains Dr. Jamison. Its a different approach than most other anti-tumor drugs, which target dividing cells or the development of blood vessels within the tumor. Since normal cells use sugars or fats for energy and cancer cells rely on glucose, the real key here is that Apatone resembles glucose. As Apatone preferentially accumulates in cancer cells, it also supplies quinone that weakens and can destroy the cancer cell from within.

The bottom line is: Apatone selectively targets and kills tumor cells using non-toxic biochemistry that protects surrounding healthy tissue.

Licensed in 2004 to IC-MedTech, Inc., a California-based biotechnology company, the first clinical trial began in 2005 to evaluate the drug in prostate cancer patients. The clinical studies, which were conducted at Summa Health System in Akron, Ohio and with Dr. Ananias Diokno at William Beaumont Hospital in Royal Oak, Mich., examined the safety and effectiveness in 17 end-
'/>"/>

Contact: Julie Uehara
ueharaj@summa-health.org
330-375-7117
Summa Health System
Source:Eurekalert

1

GOOD

Page: 1 2 3

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers identify the early makers of Neonatal Sepsis
4. OHSU Researchers Announce New Discovery
5. Researchers Identify Gene Connected To Bipolar Disorder
6. Ecstasy shrinks brain!!-researchers unveil the secrets of MDMA.
7. Researchers trick Alzheimers Enzyme
8. Researchers find new HIV hiding place
9. Gene researchers make Malaria-resistant mosquito
10. New Hair in 15 Days Could Now Be A Possibility Say Researchers
11. Researchers developed world’s smallest toothbrus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2008)...STON, Nov. 21 The Univ...ed the beginning of a collaborative effort to erad...hip for Breast Cancer Awareness and Research of th...First Lady of the United States, and Vivian Fernan..., Joining M. D. Anderson in the initiative are t...
(Date:11/21/2008)...4% Shareholders Intend To Vigorously Protect Inves...CINNATI, Nov. 21 Dr. St...led an amendment to their Schedule 13D with the U....previously filed a 13D disclosing ownership of 11....erates 77 LasikPlus fixed-site laser vision correc...
(Date:11/21/2008)...NKLIN LAKES, N.J., Nov. 21 /PRNewswire-FirstCall/ ...for medical intervention in treating 88 percent of...rcent of Americans treated for a chronic condition...pending and 75 percent of all medical costs. A pr...years by Medco Health Solutions, Inc. (NYSE: MHS...
(Date:11/21/2008)...eriments in mice find running increases production...1 (HealthDay News) -- In experiments in mice, exer...ion of brain stem cells usually seen with aging, T...restoration of the brain,s ability to stave off ag...tore a neurochemical that is essential for the pro...
Breaking Medicine News(10 mins):Health News:First Lady Laura Bush's Partnership for Breast Cancer Awareness and Research Extends to Panama 2Health News:First Lady Laura Bush's Partnership for Breast Cancer Awareness and Research Extends to Panama 3Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 2Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 3Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 4Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 5Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 6Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 7Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 2Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 3Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 4Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 5Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 6Health News:Exercise Keeps the Brain Young 2
...ys alert even if there is no sound (silence). The ...ng out for a sound. Pierre Fonlupt and Julien Voi...ional research institute. He studied the brain act...th the help of Magnetic Resonance Imaging. // It ...
...arch at the sleep and Chronobiology Laboratory in ...that mental skills performed immediately after get...He also explains that this is due to the fact that...ing moments might resemble as if you have been int...
...munity with regard to locating a care facility in ...g to the Mental Health Council // . The Western Au...l for having reversed the approval given to the 20...as expressed fears that violent inmates of the hou...
...am from McMaster University in their clinical tria...of Antiarrhythmic drugs such as amiodarone combine...educe the painful shocks in ventricular arrhythmia...fibrillator (ICD). ICD treatment produces high vol...
Other Medicine News:Health News:Sleep Inertia Resembles Intoxication 2
(Date:11/20/2008)...way, November 20 The Scandinavian-...s announced results of studies on its,lead antimi...ashington, DC,the studies showed that the novel ...idal effect, significantly better towards killing ...than marketed gold standard drugs. In,addition to...
(Date:11/19/2008)....Y., Nov. 19 Biotech scientists in...oxicology research to better understand the effect...ystems, reports Genetic Engineering & Biotech...ed in figuring out a new compound,s mechanism of a...ology technique, according to the November 15 issu...
(Date:11/18/2008)...ov. 18 Arlington Medical Resources... for the pharmaceutical and diagnostic,imaging in...ng,s Privigen was,sold in the U.S. during the thi...of intravenous immune globulin (IVIG) and was laun...uct created from the blood plasma of thousands,of...
(Date:11/13/2008)...uggests Nutritional Supplements Prior to Surgery, ...wswire/ -- Identifying,malnutrition before surgery...ouring will significantly decrease surgical compli...ality and boost patient energy levels,according t...onstructive,Surgery(R), the official medical journ...
Breaking Medicine Technology:Lytix Presents LTX-109 Anti-Microbial Data at ICAAC 2GEN Reports on the Trend Toward Predictive Toxicogenomics 2Over $10 Million of CSL Behring's Privigen Was Sold in the U.S. During the Third Quarter of 2008 2Plastic Surgeons Warn of Malnutrition in Body Contouring Patients 2Breakthroughs Offer Hope to MS Patients 23300 1Breakthroughs Offer Hope to MS Patients 23300 2Breakthroughs Offer Hope to MS Patients 23300 3Treatment delays result in poor outcomes for men with breast cancer 3900 1Treatment delays result in poor outcomes for men with breast cancer 3900 2Want to fly 3F Dont copy the birds and the bees 3898 1Want to fly 3F Dont copy the birds and the bees 3898 2Topical oral syrup prevents early childhood caries 23298 1
...ata for New Combination , , , , , PARSIPPANY, NJ...blocker,amlodipine besylate with the angiotensin r...nificant mean reductions in,seated systolic and di...on, according to data presented at the American So... Scientific Meeting and,Exposition (ASH 2007). Th...
...rscores Impact of Disease on Work Status and,Produ...tCall/ -- Findings,presented today at Digestive Di...s of the ACT trials (Active Ulcerative Colitis 1,&...rely active,ulcerative colitis (UC) who had respon...se of the trials maintained,improvement in their c...
Other Medicine Technology:Amlodipine and Olmesartan Study Results Released;Late Breaker,Presented at American Society of Hypertension Twenty-Second Annual,Scientific Meeting (ASH 2007) 2Amlodipine and Olmesartan Study Results Released;Late Breaker,Presented at American Society of Hypertension Twenty-Second Annual,Scientific Meeting (ASH 2007) 3Amlodipine and Olmesartan Study Results Released;Late Breaker,Presented at American Society of Hypertension Twenty-Second Annual,Scientific Meeting (ASH 2007) 4Long-Term Extension of Ulcerative Colitis Study Shows Remicade,Responders Maintained Improvement Through Two Years of Follow-Up 2Long-Term Extension of Ulcerative Colitis Study Shows Remicade,Responders Maintained Improvement Through Two Years of Follow-Up 3Long-Term Extension of Ulcerative Colitis Study Shows Remicade,Responders Maintained Improvement Through Two Years of Follow-Up 4Long-Term Extension of Ulcerative Colitis Study Shows Remicade,Responders Maintained Improvement Through Two Years of Follow-Up 5Long-Term Extension of Ulcerative Colitis Study Shows Remicade,Responders Maintained Improvement Through Two Years of Follow-Up 6Long-Term Extension of Ulcerative Colitis Study Shows Remicade,Responders Maintained Improvement Through Two Years of Follow-Up 7Long-Term Extension of Ulcerative Colitis Study Shows Remicade,Responders Maintained Improvement Through Two Years of Follow-Up 8Long-Term Extension of Ulcerative Colitis Study Shows Remicade,Responders Maintained Improvement Through Two Years of Follow-Up 9
...ts name from its first known site of origin, the p...nd to anti-chymotrypsin (PSA-ACT) and other compou...patients with prostate cancer, benign prostatic hy..., PSA serum levels appear to correlate with the vo...
The Bard Ellik Bladder Evacuator is designed for ease of maneuverability during the removal of tissue sections during transurethral prostatectomy, TURPs, bladder biopsy, etc.
The Urology C-Arm Table features motorized actuation of height, X-Y, lateral roll and Trendelenburg motions of the tabletop, and is fully accessorized for urologic procedures.
UROSKOP Access, the dedicated urodiagnostic table with truly unrestricted patient access optimizes nearly all diagnostic and interventional procedures.
Medicine Products: