Navigation Links
Researchers attack stem cells that cause colon cancer
Date:4/28/2010

Many of the colon cancer cells that form tumors can be killed by genetically short-circuiting the cells' ability to absorb a key nutrient, a new study has found. While the findings are encouraging, the test tube study using human colon cancer cells also illustrates the difficulty of defeating these cells, known as cancer stem cells (CSCs).

"It is becoming more evident that only a small number of cells in the tumor are capable of forming the tumor, namely the cancer stem cells," said one of the study's authors Adhip P.N. Majumdar of the VA Medical Center and Karmanos Cancer Institute, Wayne State University in Detroit. "So the new strategy is to eliminate the cancer stem cells and thus lower the recurrence of cancer."

Colorectal cancer remains the third deadliest cancer in the U.S. There are 147,000 new cases of colorectal cancer each year, and 49,920 deaths, according to the American Cancer Society. About half of all cancers, including colon cancer, reoccur within five years of treatment, Majumdar said.

Majumdar will present the study, "IFG-1R regulation of colon cancer stem cells," on Wednesday, April 28 at the Experimental Biology 2010 conference. The presentation is part of the cancer stem cell track sponsored by the American Society for Investigative Pathology. The conference takes place April 24-28 at the Anaheim Convention Center. Majumdar carried out the study with Yingie Yu and Bhaumik B. Patel, who are also with Wayne State University.

Tumor factories

Unlike most cells in the body, which are programmed to die after dividing a number of times, normal adult stem cells have a remarkable ability to renew themselves by dividing almost without limit. In addition to this ability to replicate, they can also develop into many different types of cells, such as new heart muscle cells or intestinal cells. In the mature organism, stem cells play a critical role of renewal, replacing dead cells and repairing tissue.'/>"/>

Contact: Donna Krupa
media@faseb.org
714-765-2012
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Nutrition researchers to develop new growth charts for children with Down syndrome
2. MU researchers show potential for new cancer detection and therapy method
3. Researchers successfully lower radiation dose associated with pediatric chest CT scans
4. Researchers identify a new breast and ovarian cancer susceptibility gene
5. Researchers show that nitric oxide-donating naproxen can boost colorectal cancer prevention
6. Vitamin K may protect against developing non-Hodgkins lymphoma, say Mayo Clinic researchers
7. UAB researchers find 4 biomarkers important in colorectal cancer treatment prognosis
8. UAB researchers find 4 biomarkers important in colerectal cancer treatment prognosis
9. USC researchers discover new molecular subtype of brain cancer
10. Plant pathogen genetically tailors attacks to each part of host, say Stanford researchers
11. Researchers find compound effective in destroying antibiotic-resistant biofilms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... Australian researchers reveal that sudden, acute episodes of low ... as temperature, humidity, air pressure, wind direction and precipitation. ... a journal of the American College of Rheumatology (ACR), ... increases with higher wind speed or wind gusts, but ... World Health Organization (WHO) nearly everyone experiences low back ...
(Date:7/9/2014)... School of Medicine at the University of Pennsylvania in ... an $8 million grant from the National Cancer Institute ... (PDT) in patients with malignant pleural mesothelioma, a rare, ... in the lining of the lungs and is caused ... fund a clinical trial and additional studies looking at ...
(Date:7/9/2014)... that captures heretofore hidden ways that cells are regulated, ... makes breast cancer cells more likely to metastasize. , ... in part by blocking two other proteins that are ... two disease processes could have unexpected ties. , ... of Nature , points to the possibility of ...
(Date:7/9/2014)... Center paint a relatively optimistic picture of women,s chances ... spread to the chest wall or skin, but not ... regardless of size and whether they have involved lymph ... called "locally advanced" tumors, suggesting that they are a ... Locally advanced breast cancers of this and other types ...
(Date:7/9/2014)... The Miriam Hospital have found that people with ... depressed have difficulty sticking to a pulmonary rehabilitation ... women, and screening and brief treatment of depression ... study and its findings are published in print ... obstructive pulmonary disease is a common and often ...
Breaking Medicine News(10 mins):Health News:Low back pain? Don't blame the weather 2Health News:Penn mesothelioma program receives $8 million NCI grant 2Health News:Protein pushes breast cancer cells to metastasize 2Health News:Protein pushes breast cancer cells to metastasize 3Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 2Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 3Health News:Miriam Hospital study examines effect of depressed mood on pulmonary rehab completion 2
... Ph.D., a senior research scientist in the Department of ... Park, has been chosen to receive a 2009 Astellas ... Chemical Society, is given to individuals who have made ... their work in the chemical and related sciences. ...
... ... Carestream Health will Share Insights and Best Practices for Developing an Intelligent Portfolio ... Austin, Texas ... management solutions, will host a case study webinar discussing best practices for increasing ...
... , U.S. Rep. ... , WASHINGTON, Dec. 10 The Federal Employees Health Benefits ... American Federation of Government Employees, (AFGE) "Inside Government" radio program. The ... on Federal News Radio at www.federalnewsradio.com ...
... Speaker Nancy Pelosi issued the following statement today applauding ... Appropriations Act lifting the ban on federal funding for syringe ... bill passed the House this afternoon by a vote of ... syringe exchange could not be more clear. As Dr. Anthony ...
... Savient Pharmaceuticals, Inc. (Nasdaq: SVNT ) today announced that ... Morgan Healthcare Conference on Monday, January 11, 2010 at 2:30 p.m. ... Francis Hotel in San Francisco, CA. , Individuals can ... section of the company,s web site www.savient.com . Following ...
... may help avert drug errors, study authors suggest, , ... finds that even adults who know what medicines they ... getting in the hospital. , Forty-four percent of patients ... that was not actually prescribed. A patient who normally ...
Cached Medicine News:Health News:Planview and Carestream Health Discuss the Intelligent Portfolio on December 17 Webinar 2Health News:Planview and Carestream Health Discuss the Intelligent Portfolio on December 17 Webinar 3Health News:FEHBP Open Enrollment Period to be Discussed on Special Rebroadcast of 'Inside Government' 2Health News:Pelosi: Lifting the Ban on Federal Funding for Syringe Exchange is a Victory for Science and for Public Health 2Health News:Most Hospital Patients Don't Know What Meds They're Taking 2Health News:Most Hospital Patients Don't Know What Meds They're Taking 3
(Date:1/14/2014)... /PRNewswire-iReach/ -- Acumed,s new SLIC Screw System - a ... to place and insert the screw accurately - offers ... ligament) repair or reconstruction as it holds the bones ... http://photos.prnewswire.com/prnh/20140114/MN45636 ) The SLIC Screw ...
(Date:1/14/2014)... 2014   NuAire , a manufacturer of ergonomically designed laboratory ... Koki of Japan to sell and ... . NuAire will utilize its network of sales professionals throughout ... to offer assistance in application use, product benefits and ...
(Date:1/14/2014)... N.Y. , Jan. 14, 2014   Oligomerix, Inc. , ... modifying therapeutics for Alzheimer,s disease (AD) and related neurodegenerative ... to Valhalla, NY as of ... laboratory space at New York Medical College. ...
Breaking Medicine Technology:Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 3NuAire announces sales and service of Hitachi Koki centrifuges in North America 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2
... senior health policy analyst for Consumers Union, will urge Congress ... before the House Energy & Commerce Health Subcommittee.  The ... of the Medical Device User Fee Act beginning at 10:15 ... Recent safety problems with metal hip implants ...
... LA JOLLA, Calif., Feb. 15, 2012 Celladon ... and development of innovative treatments for cardiovascular diseases, ... million equity financing to advance its lead investigational ... failure. The financing was led by new investor ...
Cached Medicine Technology:Consumers Union to Testify for Stronger Medical Device Safety Oversight at House Hearing Today 2Consumers Union to Testify for Stronger Medical Device Safety Oversight at House Hearing Today 3Celladon Corporation Completes $43 Million Financing to Advance MYDICAR® for the Treatment of Heart Failure 2Celladon Corporation Completes $43 Million Financing to Advance MYDICAR® for the Treatment of Heart Failure 3
... Delivers the advanced performance benefits ... strength, versatility, and durability ... that augments the effectiveness of ... floor reconstruction. Comprised of sterile, ...
... (also known as the VOCARE) Bladder System ... used by people with spinal cord injuries ... demand. A secondary use of the device ... promote penile erection.,The Bladder System includes surgically ...
Used for dilation of a tract to the kidney for removal of stones. Supplied sterile in peel-open packages. Intended for one-time use....
... Urinary Control offers a revolutionary approach ... symptoms of overactive bladder, including urinary ... urgency-frequency alone or in combination in ... not tolerate more conservative treatments. Medtronic ...
Medicine Products: