Navigation Links
Researchers attack stem cells that cause colon cancer
Date:4/28/2010

Many of the colon cancer cells that form tumors can be killed by genetically short-circuiting the cells' ability to absorb a key nutrient, a new study has found. While the findings are encouraging, the test tube study using human colon cancer cells also illustrates the difficulty of defeating these cells, known as cancer stem cells (CSCs).

"It is becoming more evident that only a small number of cells in the tumor are capable of forming the tumor, namely the cancer stem cells," said one of the study's authors Adhip P.N. Majumdar of the VA Medical Center and Karmanos Cancer Institute, Wayne State University in Detroit. "So the new strategy is to eliminate the cancer stem cells and thus lower the recurrence of cancer."

Colorectal cancer remains the third deadliest cancer in the U.S. There are 147,000 new cases of colorectal cancer each year, and 49,920 deaths, according to the American Cancer Society. About half of all cancers, including colon cancer, reoccur within five years of treatment, Majumdar said.

Majumdar will present the study, "IFG-1R regulation of colon cancer stem cells," on Wednesday, April 28 at the Experimental Biology 2010 conference. The presentation is part of the cancer stem cell track sponsored by the American Society for Investigative Pathology. The conference takes place April 24-28 at the Anaheim Convention Center. Majumdar carried out the study with Yingie Yu and Bhaumik B. Patel, who are also with Wayne State University.

Tumor factories

Unlike most cells in the body, which are programmed to die after dividing a number of times, normal adult stem cells have a remarkable ability to renew themselves by dividing almost without limit. In addition to this ability to replicate, they can also develop into many different types of cells, such as new heart muscle cells or intestinal cells. In the mature organism, stem cells play a critical role of renewal, replacing dead cells and repairing tissue.'/>"/>

Contact: Donna Krupa
media@faseb.org
714-765-2012
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Nutrition researchers to develop new growth charts for children with Down syndrome
2. MU researchers show potential for new cancer detection and therapy method
3. Researchers successfully lower radiation dose associated with pediatric chest CT scans
4. Researchers identify a new breast and ovarian cancer susceptibility gene
5. Researchers show that nitric oxide-donating naproxen can boost colorectal cancer prevention
6. Vitamin K may protect against developing non-Hodgkins lymphoma, say Mayo Clinic researchers
7. UAB researchers find 4 biomarkers important in colorectal cancer treatment prognosis
8. UAB researchers find 4 biomarkers important in colerectal cancer treatment prognosis
9. USC researchers discover new molecular subtype of brain cancer
10. Plant pathogen genetically tailors attacks to each part of host, say Stanford researchers
11. Researchers find compound effective in destroying antibiotic-resistant biofilms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2015)... ... ... BeverlyD, owner and founder of BeverlyD Luxe Organic Hair Care, has announced her ... to kick off the campaign for healing and Well-Being. , BeverlyD has helped women ... of raw, organic hair care products, as well as her book, Hair Now!— The ...
(Date:7/31/2015)... ... July 31, 2015 , ... Ticket Down is a reputable source of authentic tickets ... Garden Arena. Fans of every genre of music will have an act they are ... day of the festival, the following artists will perform: Sam Smith, Coldplay, Kenny Chesney, ...
(Date:7/31/2015)... ... ... Ticket Down is a reliable source for authentic tickets for the 2015 ... festival will end on Sunday, August 2nd. , Music fans have traveled ... unique and unbelievably popular festival attracts the best in entertainment from around the world. ...
(Date:7/31/2015)... ... July 31, 2015 , ... The 2nd annual Ride to Fight On ... on October 3, 2015. The Ride to Fight On is a cycling fundraiser that ... Healthcare, The West Clinic and The University of Tennessee Health Science Center. A health ...
(Date:7/31/2015)... ... July 31, 2015 , ... ... Group, Inc. has re-branded their social media profiles to better connect with the ... consumers to communicate, find information, share insights and opinions. The Rally Insurance Group, ...
Breaking Medicine News(10 mins):Health News:March4thforWellBeing Foundation Kickoff 2Health News:Cheap 2015 iHeartRadio Music Festival Tickets in Las Vegas at MGM Grand Garden Arena: Ticket Down Slashes Ticket Prices on the iHeart Radio Music Festival in Vegas 2Health News:Cheap 2015 iHeartRadio Music Festival Tickets in Las Vegas at MGM Grand Garden Arena: Ticket Down Slashes Ticket Prices on the iHeart Radio Music Festival in Vegas 3Health News:Cheap 2015 Lollapalooza Tickets: Ticket Down Slashes Ticket Prices on Lollapalooza Tickets at Grant Park in Chicago for Saturday, August 1st and Sunday, August 2nd 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 3Health News:Rally Insurance Group, Inc. Connects to Customers Through Re-branded Social Media Profiles 2
... Jeffrey A. Toretsky, M.D., a pediatric oncology physician ... Center has received a prestigious Clinical Scientist Award ... (BWF). The $750,000 award, one of only 13 ... independent physician-scientists who are dedicated to translational research ...
... Medicare Strike Force, WASHINGTON, March 7 A ... and operators of two durable medical,equipment companies and a ... Alice S. Fisher of the Criminal Division and,U.S. Attorney ... today., After a five week trial in Miami, ...
... Longs Drug,Stores Corporation (NYSE: LDG ) today ... vice president and chief operating officer, effective,immediately. He ... Vasos will,be responsible for store operations, marketing, merchandising, ... 2001 as senior vice president of marketing. He,was ...
... activates p53 tumor-suppressor function without causing DNA damage , , ... targets a protein interaction involved in many types of ... , In cell cultures, the small-molecule inhibitor MI-219 was ... protein p53 from being blocked in the presence of ...
... This release is available in Spanish . , ... Health from the University of Granada have ... conclusion they have come to is that an efficient response ... of the cases caused by three of the most frequent ...
... Telehealth capabilities to the ... help across Canada., TORONTO, March 7 /PRNewswire/ - Healthanywhere, ... they have partnered with We,Care Health Services Inc. "We Care" ... services for those with chronic diseases,and their caregivers. We Care ...
Cached Medicine News:Health News:Lombardi Cancer Center's Toretsky awarded prestigious Burroughs Wellcome Fund Award 2Health News:Miami Jury Convicts Physician and Three Business Owners of Medicare Fraud 2Health News:Miami Jury Convicts Physician and Three Business Owners of Medicare Fraud 3Health News:Longs Drug Stores Announces Todd Vasos Executive Vice President and Chief Operating Officer 2Health News:Researchers Design Promising Cancer Drug 2Health News:An efficient response in primary care would reduce the use of hospitals by elderly people 2Health News:We Care Health Services Inc. partners with IgeaCare Systems Inc. to deliver Healthanywhere(TM) for Chronic Disease Management in Canada. 2Health News:We Care Health Services Inc. partners with IgeaCare Systems Inc. to deliver Healthanywhere(TM) for Chronic Disease Management in Canada. 3
(Date:7/31/2015)... , July 31, 2015 ... decades of experience, the domestic pharmaceutical industry is strong, ... manufacture products to high international standards. One ... known is in sub-Saharan Africa: Morocco has quietly become ... South Africa . Indeed, Moroccan pharma ...
(Date:7/31/2015)... 31, 2015  Xencor, Inc. (NASDAQ: XNCR ), ... the treatment of autoimmune diseases, asthma and allergic diseases, ... S. Hata to its board of directors. ... corporate development is a tremendous asset to our board," ... executive officer of Xencor. "Xencor faces a range of ...
(Date:7/30/2015)... International Inc. (NYSE: MTD ) today announced second ... , Sales in local currency increased 3% ... sales decreased 4% as currency reduced sales growth by ... diluted share as reported (EPS) were $2.73, compared with ... , an increase of 9% over the prior-year ...
Breaking Medicine Technology:PharmaBoardroom Releases New Morocco Pharmaceuticals Report 2PharmaBoardroom Releases New Morocco Pharmaceuticals Report 3Xencor Appoints Yujiro S. Hata to Board of Directors 2Xencor Appoints Yujiro S. Hata to Board of Directors 3Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 2Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 3Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 4Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 5Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 6Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 7Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 8Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 9Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 10Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 11Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 12Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 13Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 14
... Feb. 19 A natural health company located ... results of,recent clinical studies indicating their oxygen colon ... and Irritable Bowel,Syndrome. In fact, the scientific data ... 85% MORE EFFECTIVE AT ELIMINATING SYMPTOMS,THAN TRADITIONAL LAXATIVES ...
... Feb. 19 Compendia Bioscience, Inc.,today announced results ... expanding commitment from all major customers and the ... its customer roster. The new,customers and existing customer ... increase, with similar growth forecasted for 2008., ...
Cached Medicine Technology:Oxygen Relieves IBS and Constipation Symptoms in New Clinical Studies 2On Second Anniversary, Compendia Bioscience Announces Significant Revenue Growth, Completion of Product Milestone and Expansion of Pharma Customer Commitments 2On Second Anniversary, Compendia Bioscience Announces Significant Revenue Growth, Completion of Product Milestone and Expansion of Pharma Customer Commitments 3
... many patients with a diseased heart, the only therapy ... heart transplant. However, donor organs are not always readily ... they are on the waiting list for a donor ... can save the life of a patient. On the ...
... InstaTest AFP is an immunochromatographic in ... protein (AFP) in human serum. AFP is ... 67,000 to 74,000 D. Its normal concentration ... concentrations are associated with hepatoma and ovarian, ...
... STA Compact is a ... coagulation analyser for clotting, ... based .coagulation tests.The medium-throughput ... of primary tubes, 45 ...
... Our high-quality MPD Lancets are designed with ... the tri-bevel, thin gauge needle with its ... smoother, less painful penetration without tearing the ... body is easy to grip, even for ...
Medicine Products: