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Researchers at the Gladstone Institutes find novel approach to reactivate latent HIV
Date:6/5/2014

quire multiple rounds of treatment, and these new results suggest that noise-enhancing compounds may allow each round of treatment to be more effective at getting HIV to reveal itself. Additional screens for noise-enhancing activity may identify compounds that synergize with activators even better and are more efficient at reactivating the virus in order to eliminate it for good.

"The implications for using noise also extend far beyond HIV reactivation, since random cellular activity contributes to a wide range of processes, from antibiotic persistence to cancer metastasis", said Dr. Weinberger. "Thus, this approach could represent a new tool for drug discovery across multiple fields."


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Contact: Ann Carollo
ann.carollo@gladstone.ucsf.edu
415-734-2008
Gladstone Institutes
Source:Eurekalert

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