Navigation Links
Researchers at LSTM part of the international team to sequence the tsetse genome

Researchers from LSTM are among those who have sequenced the genome of a species of tsetse fly (Glossina morsitans). The outcomes of this research will be invaluable to understanding more about the tsetse and other insect vector biology, knowledge which can be applied to improving the current vector control methods and may lead to more effective and affordable control strategies.

A paper summarising some of the findings will be published in the journal Science today, with more specific and in depth analyses of various aspects of tsetse biology being published as a collection of 10 papers within the PLOS family of journals.

The tsetse fly is the vector for African trypanosomiasis, a potentially fatal disease in people (sleeping sickness) and livestock (Nagana), throughout sub-Saharan Africa, with an estimated 70 million people at risk of infection. Unlike other disease vectors, such as mosquitoes and sandflies, both sexes of the tsetse fly feed exclusively on vertebrate blood, meaning that all tsetse are capable of spreading the disease. To deal with the nourishment issues arising from feeding exclusively on blood the tsetse has formed complex relationships with three different symbiotic bacteria. It is also unusual among insects as it gives birth to live young having evolved to lactate in order to provide nourishment to intrauterine offspring.

The work was carried out over a 10 year period following the formation of the International Glossina Genome Initiative in 2003. Around 146 scientists have contributed to the work, including members of the departments of Vector Biology, Parasitology and Clinical Sciences within LSTM, along with colleagues from around the world, with at least half of the contributors being from African institutions.

LSTM's Professor Mike Lehane was a member of the project leadership team and describes the significance of the work: "Human infections with African trypanosomes can be fatal if left untreated. It has not been possible to develop a vaccine for the disease due to the ability of trypanosomes to evade the mammalian immune system, this coupled with the fact that there are some significant side-effects and reports of growing resistance to current trypanocidal drug treatments means that vector control strategies remain the best hope to eliminate the disease.

"The work that has been carried out by such a large group of international researchers and scientists has not been without its challenges, but has given us detailed information on a wide range of aspects of tsetse biology. It has provided us with a vital research tool, which will be continually added to over time and may well lead to control strategies that can bring an end to suffering caused by the disease both in terms of the human cost as well as the economic losses due to affected livestock."


Contact: Clare Bebb
Liverpool School of Tropical Medicine

Related medicine news :

1. Oxygen diminishes the hearts ability to regenerate, researchers discover
2. Finnish team of researchers finds a mutation in a tumor of the jaw
3. Depressed? Researchers identify new anti-depressant mechanisms, therapeutic approaches
4. Life stressors trigger neurological disorders, researchers find
5. Penn researchers find link between sleep and immune function in fruit flies
6. Penn Medicine researchers uncover hints of a novel mechanism behind general anesthetic action
7. CU researchers discover target for treating dengue fever
8. BUSM researchers find anti-seizure drug may reduce alcohol consumption
9. Researchers identify children with emotional behavior difficulties
10. Researchers identify similarities between HIV/AIDS and opioid addiction epidemics
11. Oxytocin, the love hormone, promotes group lying, according to Ben-Gurion U. researchers
Post Your Comments:
(Date:11/28/2015)... ... 28, 2015 , ... Safe storage for contraceptive devices may not always be ... New Jersey and the other from Bradley Beach, New Jersey, there is an easy ... of having to replace NuvaRings more often than necessary. As such, it affords peace ...
(Date:11/27/2015)... CA (PRWEB) , ... November 27, 2015 , ... According ... at the recent 2015 American Dental Association meeting in Washington D.C. revolved around the ... protect a patient’s overall health. The talk stressed the link between periodontal disease (more ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... and convenient way to dispense prescription medications at home, so he invented the ... to monitor and dispense prescription medications. In doing so, it could help to ...
(Date:11/27/2015)... ... , ... MPWH, the No.1 Herpes-only dating community in the world, revealed that over 50% of ... than 3.7 billion people under the age of 50 – or 67% of the population ... global estimates of HSV-1 infection . , "The data shocks us highly!" said Michelle ...
(Date:11/27/2015)... ... 2015 , ... Keeping in mind challenges faced by parents ... consultation, has collaborated with a leading web-based marketplace for extra-curricular activities for children ... and bring advice from parenting experts within their reach. As a part of ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... --> adds "Global ... and "Investigation Report on China Repaglinide ... 2021 forecasts data and information to ... . --> ...
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ... the "2016 Future Horizons and Growth Strategies ... Supplier Shares, Country Segment Forecasts, Competitive Intelligence, Emerging ... --> --> This ... the Italian therapeutic drug monitoring market, including emerging ...
(Date:11/26/2015)... , November 26, 2015 ... the addition of the  "2016 Future ... European Cell Surface Marker Testing Market: ...  report to their offering.  --> ... addition of the  "2016 Future Horizons ...
Breaking Medicine Technology: