Navigation Links
Researchers at BMC find disability does not necessarily follow disease in living to old age
Date:2/11/2008

Boston, MA--Researchers from Boston Medical Centers (BMC) New England Centenarian Study report that for a substantial proportion of their centenarian subjects, avoiding age-related diseases (i.e. stroke, cardiovascular disease, diabetes) may not be the key to their longevity; rather, the avoidance of disability may be a key feature in their exceptional survival. These findings appear in the February 11th issue of Archives of Internal Medicine.

The researchers examined the health histories of 739 centenarians and found about one third of the subjects had age-related diseases for 15 or more years (age of onset prior to the age of 85). We expected to find that nearly all centenarians have to compress the time they are sick towards the very end of their lives, otherwise how could they get to such old age" asked senior author, Thomas Perls, MD, MPH, director, of BMCs New England Centenarian Study and associate professor of medicine at Boston University School of Medicine. One factor enabling the survival of these sick centenarians-to-be appears to be a delay or compression of their disability, he added.

Seventy two percent of the male centenarians and 34 percent of the female centenarians in this survivors-of-disease group (centenarians who developed age-related diseases prior to age 85) scored in the independent range on the Barthel Activities of Daily Living Index at the age of 97 or older. According to the researchers, for a significant proportion of people surviving to extreme old age, compression of disability, rather than morbidity is a key feature of their ability to live such long lives.

The ramifications of our findings are that among older people, morbidity and disability do not always go hand in hand, said lead author Dellara Terry, MD, MPH, co-director of the New England Centenarian Study and assistant professor of medicine at Boston University School of Medicine. Eventually being able to understand the underlying mechanisms for delaying disability in the presence of important age related diseases could lead to better prognostication and perhaps even therapies, she added.

The researchers also found that though far fewer in number, male centenarians tend to have significantly better cognition and physical function than their female counterparts. One possible explanation for this may be that women are more resilient compared to men when it comes to aging. Thus, for a man to live to 100 or older, he must be in truly fantastic shape as close to the end of his life, whereas, the women can better handle living with age-related illnesses.


'/>"/>

Contact: Allison Rubin
allison.rubin@bmc.org
617-638-8491
Boston University
Source:Eurekalert

Related medicine news :

1. Oregon researchers discover a mechanism leading to cleft palate
2. Penn childhood obesity researchers panelists at AAAS Town Hall Event
3. Researchers at Pulmonary Associates to study airway bypass procedure for severe emphysema
4. European blood researchers receive award to pursue research opportunities in US
5. SfN releases Best Practices for Protecting Researchers and Research
6. Researchers discover new battleground for viruses and immune cells
7. Researchers find less invasive, highly accurate methods
8. MSU researchers make new discoveries on what does and doesnt affect immune system
9. Researchers query FDA about updating requirements for drug approval
10. MITs McGovern Institute researchers awarded $8.5M to study brain basis of autism and dyslexia
11. U of M researchers discover a pathway to turn off immune system cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... Portland, Maine (PRWEB) , ... December 02, 2016 , ... ... support group for caregivers of those affected by autism spectrum disorder (ASD) and other ... and Easter Seals Maine, will give parents and other caregivers the opportunity to share ...
(Date:12/2/2016)... ... December 02, 2016 , ... U.S. Surgeon General, Dr. Vivek Murthy, ... Murthy explains how he was inspired to practice medicine at an early age by ... about more than making diagnoses and prescribing medicine,” he states. “It is about building ...
(Date:12/2/2016)... ... December 02, 2016 , ... Mediaplanet’s newest campaign, “Digestive Heath,” ... living proof that attitude and determination can combine into the most remarkable achievements. ... the holidays. This campaign will offer patients a new-found hope, by seizing the ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... More than ... and while 84 percent of parents report speaking with their child about sex related ... sexually transmitted diseases. , Mediaplanet is proud to announce the launch of its second ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... of its SaaS LIMS, CloudLIMS Lite. CloudLIMS Lite helps biobanks, clinical, research and ... storing, shipping and disposal. The new version is a faster and a more ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... , Dec. 2, 2016  Maxor National Pharmacy Services, ... of Pharmaceutical Specialties, Inc. ("PSI").  The combination of ... Georgia -based PSI bring together both company,s clinical ... manufacturers, and payers an industry-leading specialty pharmacy. About ... , , ...
(Date:12/2/2016)... 2, 2016 Lianluo Smart Limited (Nasdaq: ... Company") which develops, markets and sells medical devices ... China and international markets, recently attended ... Treatment New Progress Forum, co-hosted by the Institute ... , Guangdong Provincial People,s Hospital and Cardiology ...
(Date:12/2/2016)... Dec. 1, 2016 The concept of rare diseases ... given to this sector has been taking shape in ... the political aspects and initiatives related to orphan medicinal products ... the level of member states individually. Many member states in ... the space of orphan medicinal products, the result of which ...
Breaking Medicine Technology: