Navigation Links
Researchers advocate for more education and attention regarding rare breast cancer
Date:10/19/2010

sts have often considered IBC a type of locally advanced breast cancer, the reality is that IBC is a distinct disease. "A typical advanced breast cancer has a mass or nodule that grows over months or years, and eventually involves most of the breast and could show also with some redness," Cristofanilli says. "With IBC, you have a tumor that becomes clinically evident in just a few weeks sometimes women describe it as just a few days. The breast is red and inflamed, but there is no fever; within a few days, the cancer is already in the lymph nodes and there is no palpable mass. So if you picture these two situations, you clearly see there is no resemblance."

The difference in presentation and symptoms suggests that IBC has a distinct underlying biology, relative to locally-advanced breast cancer. And many years of research have shown that IBC does not respond to therapies used to treat other forms of breast cancer.

New and more effective therapies are in the works though, according to Cristofanilli and first author Fredika Robertson, Ph.D., professor in the Department of Experimental Therapeutics at The University of Texas MD Anderson Cancer Center. Basic science researchers, such as Robertson, are pinpointing molecular pathways that drive the formation and growth of IBC, and new agents targeted against those pathways are in development.

For example, on-going clinical trials are testing lapatinib, a tyrosine kinase inhibitor that blocks two signaling pathways that are frequently hyperactive in IBC. "Lapatinib is one of the few drugs that shows activity as a single drug in IBC, but this is still an evolution," Cristofanilli says. "The paper addresses some of the areas where we expect to see novel agents come and the direction we will go in the next few years."

"I think the future is bright if we are all able to come together and recognize that there is a need to put resources and research into this disease," he says. "And many r
'/>"/>

Contact: Diana Quattrone
Diana.Quattrone@fccc.edu
215-728-7784
Fox Chase Cancer Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Mount Sinai researchers discover why cocaine is so addictive
2. Temperature rhythms keep body clocks in sync, UT Southwestern researchers find
3. Need a study break to refresh? Maybe not, say Stanford researchers
4. Researchers reach consensus on use of deep brain stimulation to treat Parkinsons
5. AACR to honor leading researchers at breast cancer symposium
6. Medical researchers break down costs to care for heart failure patients at the end of life
7. Researchers Pinpoint Array of Obesity Genes
8. UT Southwestern researchers create experimental vaccine against Alzheimers
9. Wistar researchers discover new class of objects encoded within the genome
10. Blood test could diagnose Alzheimers disease, UT Southwestern researchers find
11. Mayo researchers find biomarkers for personalizing radiation cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... AZ (PRWEB) December 26, 2014 ... source for the best in heating, cooling and ... for 24 hour emergency services in 2014 with ... alike know that Arizona is known for its ... company that understands the intricacies and details of ...
(Date:12/25/2014)... Dallas, TX (PRWEB) December 26, 2014 ... current state of the global Sterilizers industry with a ... statistics on the market status of the Sterilizers manufacturers ... for companies and individuals interested in the industry. This ... its definition, applications and manufacturing technology. In this part, ...
(Date:12/25/2014)... The report “Nintedanib (Colorectal Cancer) ... on the current treatment landscape, unmet needs, current ... market. Stivarga is a drug which is used ... Boehringer Ingelheim is developing nintedanib (BIBF-1120), an orally ... CRC in the US, Europe, and Japan. The ...
(Date:12/25/2014)... 25, 2014 Product liability lawsuits filed ... recall ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in ... Order issued in the U.S. District Court, Northern District ... an open conference on January 7, 2015, at the ... in West Palm Beach, Florida. The Conference is scheduled ...
(Date:12/25/2014)... the popular online supplier of wedding dresses and special occasion ... black one-shoulder cocktail dresses . In addition, all these elegant ... prices, up to 70% off. , The development ... You know, we have thousands of frequent callers in the ... can visit our website for more details. The current special ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2
... According to the infectious disease expert the afro American ... This vaccine was recently approved by the FDA //. ... Disease by researchers at The Miriam Hospital and Brown ... best ay for distributing the vaccine is through school-based ...
... The idea of subjecting drug addicts to shock therapy as ... debates and controversies. Now, the Scottish Executive is doing more ... therapy technically labeled as Neuro-Electric Therapy (NET) is executed with ... which electric pulses are sent into the brain. This is ...
... the University of Manchester, and Dr. John Read, from ... medical conferences //in London and Madrid about the link ... reviewed 40 studies of psychiatric patients and found that ... When reviewed 13 different studies of schizophrenics, they found ...
... confirmed that the bird flu virus found in poultry in ... to humans as well //. ,As chief veterinarian ... laboratory that it was the highly pathogenic H5N1 strain of ... ,This is the first report of the H5N1 virus in ...
... of two hospitals in Jedburgh and Coldstream. For along time ... part of a revamping of services //. This led to ... Jedburgh and the 14-bed complex at Coldstream. But the campaigners ... The Jedburgh Provost Len Wyse said that the decision would ...
... the quake affected areas of Indonesia. It is a Noncommunicable ... Clostridium tetani. It is otherwise called as lockjaw as ... the jaw. If not treated properly it eventually results in ... already killed 18 earthquake survivors in Indonesia. ,The ...
Cached Medicine News:Health News:Afro American Women at a High Risk of HPV and Hence Should Be Vaccinated 2
(Date:12/24/2014)... Dec. 23, 2014 In response to urgent requests ... Sierra Leone , Direct Relief delivered two ... for the treatment of local health workers who contract Ebola ... dedicated Ebola care center was constructed for foreign health care ... not available for local Sierra Leonean health workers. ...
(Date:12/22/2014)... NxStage Medical, Inc. (NASDAQ: NXTM ... announced today that the U.S. Food and Drug ... perform hemodialysis overnight while the patient is at ... System One is the first and only hemodialysis ... Home nocturnal hemodialysis is an ...
(Date:12/22/2014)... --Research and Markets ( http://www.researchandmarkets.com/research/hmlfbq/investment ) ... Analysis of the US Medical Device Sector " ... http://photos.prnewswire.com/prnh/20130307/600769 This analysis ... identifies the key trends and rationale for undertaking ... and acquisitions. The study will be ...
Breaking Medicine Technology:First Ebola Treatment Unit for Local Health Workers Arrives in Sierra Leone 2NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 2NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 3Investment Analysis of the US Medical Device Sector 2
... , SALT LAKE CITY , March 15 Otix Global, Inc. (Nasdaq: OTIX ), announced today that it ... to April 11, 2011 , modifies covenants, and revises the borrowing base formula which allows the Company to obtain additional funds ... ... , ...
... March 14 Siemens Healthcare addresses the ... 59th Annual Scientific Session of the American College of Cardiology ... booth #1018. With a commitment to excellence, Siemens empowers its ... world of cardiology, and help them meet their strategic and ...
Cached Medicine Technology:Otix Global, Inc. Extends Term of Loan and Security Agreement With Silicon Valley Bank 2Otix Global, Inc. Extends Term of Loan and Security Agreement With Silicon Valley Bank 3Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 2Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 3Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 4Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 5Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 6Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 7Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 8Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 9Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 10Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 11Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 12Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 13Siemens Highlights Its Commitment to Excellence in Cardiology at ACC 2010 14
Cushing forceps. Insulated....
Scleral knives designed for trabeculectomy and groove type incisions, scleral standard USA size....
Angled 60 degree blades 5.5 mm....
Fechtner Trabeculectomy Marker...
Medicine Products: