Navigation Links
Researchers Use New Techniques to Assess PTSD
Date:12/8/2009

Findings with Newly Returning Veterans

NASHVILLE, Tenn., Dec. 8 /PRNewswire-USNewswire/ -- Veterans of Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) frequently experience high rates of PTSD along with symptoms of depression and pain. However, little is known about why these symptoms occur together or the most effective treatments that can be used to alleviate them. One approach that may yield new insights is to search for biomarkers -- indicators of a biological state that can be easily and reliably measured in people with an illness -- to see if their presence or absence can predict symptoms that an individual will experience and identify optimal treatment strategies.

Dr. Christine Marx and her team at Duke University and the Durham VA Medical Center sought to determine if there are biomarkers associated with PTSD symptoms. They hypothesized that veterans who have PTSD (and who often experience depression and pain symptoms) show changes in neurosteroids, which are brain chemicals thought to play a key role in responsiveness to stress.

Dr. Marx based her approach on prior work involving animal models showing that levels of neurosteroids found in blood samples accurately reflect levels found in the brain. Dr. Marx measured blood neurosteroid levels in 90 male OEF/OIF veterans to examine whether they may be predictive of PTSD, depression, and pain symptoms. She found that several candidate biomarkers could be important to identifying the changes that occur in the brain with PTSD, which could aid in the development of more effective treatments.

"The neurosteroid allopregnanolone looks like a particularly promising biomarker that we might use to help assess symptom severity in PTSD, depression, and pain disorders, understand their neurobiological underpinnings, develop new treatment options, and predict therapeutic response," said Marx, an Associate Member of ACNP.

Her work was funded by the Veterans Administration, National Institutes of Health, the Department of Defense, and NARSAD.

ACNP, founded in 1961, is a professional organization of more than 700 leading scientists, including four Nobel Laureates. ACNP's mission is to further research and education in neuropsychopharmacology and related fields.

SOURCE American College of Neuropsychopharmacology


'/>"/>
SOURCE American College of Neuropsychopharmacology
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Innovative Applications of Flow Cytometry Win U.S. and European Researchers Free Accuri C6 Flow Cytometer(R) Systems
2. City of Hope Researchers Present Data on more than 30 Studies During American Society of Hematology Meeting Dec. 5 to 8 in New Orleans
3. Case Western Reserve researchers new pathway discovery published as Paper of the Week
4. Researchers find increased dairy intake reduces risk of uterine fibroids in black women
5. Wayne State Researchers Report a Possible Proofreading Step in DNA Synthesis by Observing Single Molecules of DNA Polymerase
6. Researchers identify gene that spurs deadly brain cancer
7. CWRU researchers report poor outcomes for CCI patients leaving hospitals on ventilators
8. VAI Researchers Find Long Awaited Key to Creating Drought Resistant Crops
9. Parent mentors can improve the asthmatic care of minority children, UT Southwestern researchers find
10. Researchers identify proteins in lung cancer cells that may provide potential drug targets
11. Researchers Identify Possible Causative Mutation for Crohn's Disease: Crohn's & Colitis Foundation Annual Conference to Present Emerging Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... ... May 24, 2016 , ... Educational opportunities, ... housing, with more advantaged communities providing richer opportunities. Recognizing the key role of ... school improvement policies; (b) school choice policies; (c) school desegregation policies; (d) wealth-focused ...
(Date:5/24/2016)... ... ... New Brunswick, New Jersey: This year marks Children’s Specialized Hospital ’s 125th anniversary ... anniversary, the hospital has themed the milestone “Hats Off” and kicked off the yearlong ... Saturday, May 21, at Johnson Park in Piscataway, New Jersey. , “Hats ...
(Date:5/24/2016)... ... (PRWEB) May 24, 2016 -- Grow Healthy ... Advisory Board. Joining the Grow Healthy Advisory Board team are ... embody the mission of our organization and bring talent, expertise and ... as we continue to expand our footprint as the leader in ...
(Date:5/24/2016)... ... May 24, 2016 , ... Boyd Industries, a leading supplier of ... groundbreaking new product for pediatric dentistry , at AAPD 2016, the annual conference ... May 26-29. The Concealed Delivery Unit keeps dental hand pieces and other anxiety-provoking pieces ...
(Date:5/24/2016)... ... May 24, 2016 , ... Eggsurance, the first independent, non-clinic ... its community and education hub for women considering fertility preservation, as well as ... safe and welcoming place for women to find cycle buddies, get clinic recommendations ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 2016 The innovator of ... , s first dual therapy stent, introduces catheters ... OrbusNeich, a global company specializing in the provision ... include products to treat peripheral artery disease. The JADE™ ... devices for lower limb and arteriovenous (AV) fistula intervention. ...
(Date:5/24/2016)... , May 24, 2016 Dutch surgeons ... best practices around the world and treat patients on a global ... Africa , Asia and the US ... with instant messaging and networking in a totally secure environment. ... in a war zone working together with a surgeon at Harvard ...
(Date:5/23/2016)... FLINT, Mich. , May 23, 2016 Diplomat ... the third annual Fellowship and Internship programs. The hands-on ... 12. The full-time, paid Fellowship ... Flint, Michigan . Fellows and interns are ... downtown Flint at the Riverfront ...
Breaking Medicine Technology: