Navigation Links
Researchers Use Gene to End High Blood Sugar in Mice
Date:3/18/2009

Whether method might someday help people awaits further study

WEDNESDAY, March 18 (HealthDay News) -- Delivering a gene called neurogenin3 into the livers of diabetic mice activates adult stem cells that promote steady insulin production, say researchers at the Baylor College of Medicine in Houston.

The mice had type 1 diabetes. Within a week after the gene was delivered using a disarmed virus, the researchers said, the rodents' blood sugar levels returned to normal and remained that way for the rest of their lives.

The gene triggers a two-step response. First, neurogenin3 goes into the mature liver cells and causes them to make small quantities of insulin, enough to reduce blood sugar levels to normal.

"This is a transient effect. Liver cells lose the capacity to make insulin after about six weeks," Dr. Vijay Yechoor, assistant professor of medicine-endocrinology at Baylor and the study's first author, said in a news release from the college.

Other cells that make larger amounts of insulin show up later. These cluster around the portal veins, which carry blood from the intestines and abdominal organs to the liver. These new cells, which look similar to pancreatic islet cells that normally make insulin, come from a small population of adult stem cells usually found near the portal vein, the authors said.

These stem cells normally act as reserves in case of liver injury. When the liver is damaged, the stem cells form mature liver cells or bile duct cells. But neurogenin3 changes their programming so that they become insulin-producing beta cells in the liver, the researchers said.

The study appears in the March issue of Developmental Cell.

Though the finding is important, much more research is needed before similar results might be seen in humans, Yechoor and his colleagues said.

More information

The U.S. National Diabetes Information Clearingh
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers Use Gene to End High Blood Sugar in Mice
(Date:5/19/2013)... Dalla, TX (PRWEB) May 19, 2013 ... comprehensive analysis for US, UK, Spain, Japan, Italy, ... pertaining to the molecular diagnostics laboratory practice, as ... technological trends with significant market impact during the ... of DNA probe and biochip technologies, test formats, ...
(Date:5/19/2013)... NY (PRWEB) May 19, 2013 Americans ... According to the newest American Veterinary Medical Association (AVMA) ... of American dog owners consider their dog a member ... who had said as much five years earlier. , ... dollar value of the national income dedicated to pets ...
(Date:5/19/2013)... 19, 2013 Vegas Hotel Escapes, the ... to announce the launch it's all new vacation packages ... Grand on 5/19/2013. Consumers traveling to Las Vegas will ... available on VegasHotelEscapes.com's website. Travelers will be pleased to ... competitors price. , Vegas Hotel Escapes specializes in helping ...
(Date:5/19/2013)... May 19, 2013 Passages Malibu, the ... center, has announced this week the launch of a ... brands’ social media channels. “We are always looking ... community and to get feedback regarding sobriety, what’s working ... and co-founder of the Passages Addiction Treatment Centers ...
(Date:5/19/2013)... Florida (PRWEB) May 19, 2013 ... market access, is pleased to unveil a new and ... environment that provides a powerful array of real-time communication ... in the US and abroad. , HE-Xpo is powered ... offer attendees the look and feel of being at ...
Breaking Medicine News(10 mins):Health News:Molecular Diagnostics Market - US, UK, Spain, Japan, Italy, Germany & France Analysis in New Research Report at ReportsnReports.com 2Health News:Molecular Diagnostics Market - US, UK, Spain, Japan, Italy, Germany & France Analysis in New Research Report at ReportsnReports.com 3Health News:Molecular Diagnostics Market - US, UK, Spain, Japan, Italy, Germany & France Analysis in New Research Report at ReportsnReports.com 4Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 2Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 3Health News:Passages Malibu Announces its Sobriety, Health, and Wellness Social Media Survey 2Health News:Passages Malibu Announces its Sobriety, Health, and Wellness Social Media Survey 3Health News:HealthEconomics.Com Announces HE-Xpo, a New Virtual Trade Show Devoted to Healthcare Value and Market Access 2Health News:HealthEconomics.Com Announces HE-Xpo, a New Virtual Trade Show Devoted to Healthcare Value and Market Access 3
... Universal Capital,Management, Inc. (OTC Bulletin Board: UCMT.OB), ... management and strategic growth,resources to emerging growth ... of its,holdings, iVolution Medical Systems, Inc. will ... to fruition. , ...
... Schizophrenia could be caused by faulty signalling in the ... journal Molecular Psychiatry . In the biggest study ... samples donated by people with the condition have identified ... schizophrenia patients compared to controls. , Many of these ...
... Company, Inc.,s new ,Feel Good, Light Lenses are perfect decorating pieces ... economical time. , ... (PRWEB) March 3, 2009 -- ... nation, the Flag Company, Inc. recently launched ,Feel Good, Light Lenses ...
... Bingo tickets for the Cystic Fibrosis Trust and raised over £10,000 for ... ... -- JackpotCity.com Online Bingo has ensured that both the Cystic Fibrosis Trust ... fight against this life-threatening disease. , , , , ,For over 40 ...
... Guinea The southeast Pacific nation of Papua ... diverse ecosystems on Earth, has created its first national ... tropical forest larger than Singapore. , The decision by ... local communities neighboring the newly established YUS Conservation Area, ...
... the flu vaccine and flu vaccine supplies has unveiled their annual 2009 ... , ... (Vocus) March 2, 2009 -- Nationwide Medical/Surgical , a distributor ... 2009 list of what to do if exposed to the flu virus., ...
Cached Medicine News:Health News:iVolution Medical Systems to Assist Healthcare Providers With Compliance of President Obama's Stimulus Plan 2Health News:iVolution Medical Systems to Assist Healthcare Providers With Compliance of President Obama's Stimulus Plan 3Health News:Schizophrenia linked to signaling problems in new brain study 2Health News:The Flag Company, Inc. Releases 'Feel Good' Light Lenses to Help Counter Gloomy Economic Outlook 2Health News:The Flag Company, Inc. Releases 'Feel Good' Light Lenses to Help Counter Gloomy Economic Outlook 3Health News:JackpotCity.com Online Bingo Raises Over 10,000 for Cystic Fibrosis Trust 2Health News:Papua New Guinea declares first national conservation area 2Health News:Papua New Guinea declares first national conservation area 3Health News:Papua New Guinea declares first national conservation area 4Health News:Nationwide Medical/Surgical Reveals Their Help Sheet For Those Infected with Influenza Virus 2
(Date:5/17/2013)... , May 17, 2013  Serving a region of 650,000 ... , Caribbean Imaging and Radiation Therapy (CIRT, ... capabilities with the acquisition of an Elekta Versa HD™ system, ... HD offers clinicians the versatility to deliver conventional therapies to ... also enabling treatment of highly complex cancers that require extreme ...
(Date:5/17/2013)... N.J. , May 17, 2013  PENTAX ... and Hitachi-Aloka Medical, a global leader in ultrasound ... two global companies to enable further innovation in ... years, the Hitachi-Aloka ultrasound systems and PENTAX Medical ... most trusted families of EUS systems. This agreement ...
(Date:5/17/2013)... Oramed Pharmaceuticals Inc. (NASDAQCM: ORMP) ( http://www.oramed.com ... today that the United States Food and Drug Administration ... for ORMD-0801, its oral insulin capsule. "We ... proceed," stated Nadav Kidron , CEO ... for Oramed and we look forward to continuing to ...
Breaking Medicine Technology:Puerto Rico's Caribbean Imaging and Radiation Therapy Center Orders Elekta's New Versa HD System for Treatment of Cancer Patients 2PENTAX Medical And Hitachi-Aloka Medical Continue Joint Innovation And Global Leadership In Endoscopic Ultrasound Systems 2PENTAX Medical And Hitachi-Aloka Medical Continue Joint Innovation And Global Leadership In Endoscopic Ultrasound Systems 3Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 2Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 3
... 2, 2011 Bionovo, Inc. (NASDAQ: BNVI ), ... safe and effective treatments for women,s health and cancer, today ... clinical trial of their lead drug candidate for postmenopausal symptoms, ... community at the 13th Annual World Congress on Menopause in ...
... 2011 / PRNewswire / -- Cadence Pharmaceuticals, ... focused on in-licensing, developing and commercializing proprietary products principally ... the company,s President and CEO Ted Schroeder will present ... at 1:30pm Eastern Time (10:30am Pacific Time) during the ...
Cached Medicine Technology:Bionovo to Present the Clinical Promise of Menerba (MF101) for Postmenopausal Vasomotor Symptoms at World Congress on Menopause 2Bionovo to Present the Clinical Promise of Menerba (MF101) for Postmenopausal Vasomotor Symptoms at World Congress on Menopause 3Bionovo to Present the Clinical Promise of Menerba (MF101) for Postmenopausal Vasomotor Symptoms at World Congress on Menopause 4
... Facilitates grasping and implanting the ... and within the capsular bag without ... mm long jaws are placed in ... handle. Smooth, flat, cross action handle ...
Fine 3.0 mm platformed angled 60 degrees 10 mm from angle to tip. Serrated handle with dull finish....
Puntenney curved forceps, curved, smooth 10 mm platforms....
Hatsis tying forceps, titanium, long thin tying platforms....
Medicine Products: