Navigation Links
Researchers Tackle CLL, Diabetes and Trauma-Hemorrhage,
Date:11/14/2008

Molecular Medicine, a bimonthly, biomedical journal published by The Feinstein Institute for Medical Research, strives to understand normal body functioning and disease pathogenesis at the molecular level which may allow researchers and physician-scientists to use that knowledge in the design of specific molecular tools for disease diagnosis, treatment, prognosis, and prevention. Featured in the November/December issue: “Chronic Lymphocytic Leukemia Cells Recognize Conserved Epitopes Associated with Apoptosis and Oxidation”, “Angiogenesis and Diabetes: Different Responses to Pro-Angiogenic Factors in the Chorioallantoic Membrane Assay”, and “Estradiol’s Salutary Effects on Keratinocytes following Trauma-Hemorrhage Are Mediated by Estrogen Receptor (ER)- and ER-”.

(Vocus) November 14, 2008 -- Chronic Lymphocytic Leukemia (CLL) is a disease of the B lymphocytes of the immune system. Under normal conditions, B lymphocytes (or B cells) play an important role in battling infection. CLL is a disease manifested by uncontrolled growth of these B lymphocytes. In this month’s issue of Molecular Medicine, Rosa Catera and her colleagues found that CLL cells react with cells undergoing programmed cell death (apoptosis), and those with the worst outcomes have the most potent reactivity. CLL comes in several forms and has different outcomes for patients. Some can live for years or decades with few symptoms, while others progress quickly into advanced stages of disease and thus have a shorter life expectancy.

Catera and her colleagues have been trying to unravel a curious observation that many of the antibodies in CLL patients share a similar genetic sequence, no matter where in the world they live. The finding suggests that apoptosis generates substances that could stimulate CLL cell growth. In laboratory models, they have shown that this type of reactivity is seen in a small subset of B cells, suggesting that CLL might evolve from this type of normal B lymphocyte. Chronic Lymphocytic Leukemia Cells Recognize Conserved Epitopes Associated with Apoptosis and Oxidation. Rosa Catera and colleagues can be reached at rcatera @ nshs.edu.

In other major news in the journal, scientists at INSERM in France have evidence that hyperglycemia impedes therapeutic angiogenesis, which could be a problem when designing ways to test these new treatment. Angiogenesis and Diabetes: Different Responses to Pro-Angiogenic Factors in the Chorioallantoic Membrane Assay Giovana Di Marco, Etienne Larger and colleagues can be reached at etienne.larger@college-de-france.fr. Scientists at the University of Alabama report stunning findings of estrogen receptor involvement in trauma and hemorrhage. Estradiol’s Salutary Effects on Keratinocytes following Trauma-Hemorrhage Are Mediated by Estrogen Receptor (ER)-± and ER-². Fariba Moeinpour, Irshad H Chaudry and colleagues can be reached at Irshad.Chaudry @ ccc.uab.edu.

To read the journal online and view this month’s popular podcast go to www.molmed.org. For more information contact Margot Puerta, managing editor of Molecular Medicine at 516-562-1129.

###

Read the full story at http://www.prweb.com/releases/2008/11/prweb1613334.htm


'/>"/>
Source: PRWeb
Copyright©2008 Vocus, Inc.
All rights reserved  

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers Tackle CLL, Diabetes and Trauma-Hemorrhage,
(Date:2/22/2017)... ... February 22, 2017 , ... THR ... “NANOCALM 300” Microemulsified Hemp Extract. This premier nanoemulsified CBD product utilizes Quicksilver ... the bloodstream. Far outpacing the absorption speed of all other products, ...
(Date:2/22/2017)... (PRWEB) , ... February 22, 2017 , ... ... a contract to Quality Insights to help small practices in Delaware, New Jersey, ... Program, established by the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA). ...
(Date:2/22/2017)... Cranbury, NJ (PRWEB) , ... February 22, 2017 ... ... full-service healthcare communications company, launched a new media platform connecting healthcare technology professionals ... which will be followed by a quarterly publication starting on March 1, announced ...
(Date:2/22/2017)... ... February 22, 2017 , ... Pet obesity in the U.S. ... dogs, according to the Association for Pet Obesity Prevention (APOP). During the ninth annual ... issues such as the benefits of corn and grains, value of raw and organic ...
(Date:2/22/2017)... Dallas, TX (PRWEB) , ... February 22, 2017 ... ... of security threats. Yet with so many different solutions on the market, it ... through their choices, Texas Premier Locksmith offers a complimentary security consultation. ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)... 2017 The top three ... Olympus Corporation, Nikon Corporation, and Leica Microsystems. Collectively ... the overall market in 2015. The oligopolistic market ... result-oriented research and development activities and mergers and ... on expanding their business to emerging economies as ...
(Date:2/22/2017)... and PUNE, India , February 22, 2017 ... was valued at $3,453 million in 2015 and is projected to reach $5,334 million ... implants segment held nearly two-fifths of the total market in 2015. ... ... ...
(Date:2/22/2017)... Feb. 22, 2017  Known for selling everyday ... the widow of prominent California ... know something else about the British conglomerate that makes ... by attempting to steal her late husband,s invention, business ... operated by Dr. Gilbert until his violent death in ...
Breaking Medicine Technology: