Navigation Links
Researchers Successfully Create Computer-Simulated Model for Evaluating Artificial Pancreas
Date:3/31/2009

- Key Step in Ongoing Research to Replicate Insulin-Producing Function of Healthy Pancreas for Type 1 Diabetes Patients -

SANTA BARBARA, Calif., March 31 /PRNewswire/ -- A key step toward the successful development of an artificial pancreas for patients with diabetes has been achieved, according to new research published in this month's issue of Diabetes Technology & Therapeutics.

Researchers at the University of California at Santa Barbara, Sansum Diabetes Research Institute and Stanford Medical Center have effectively created a computer-simulated system for evaluating an investigational artificial pancreas comprised of the OmniPod(R) Insulin Management System--including the OmniPod insulin pump and Personal Diabetes Manager that controls it--and a continuous glucose monitor, in this case either the FreeStyle Navigator(R) or the DexCom STS7(R). The system also includes an algorithm that automates the interaction between the pump and monitor, and facilitates the running of a variety of tests and challenges to the software and component devices. The UC Santa Barbara-developed software and algorithms are also being used with a number of other pumps and monitors in developing additional systems.

"While we still have a ways to go, this new system brings us much closer to making the artificial pancreas a reality for type 1 diabetes patients," explained lead author Eyal Dassau, PhD, Diabetes Team Research Manager at UC Santa Barbara (UCSB). "This achievement is vital--we now have a way, prior to patient trials, to fully verify and validate that an artificial pancreas can efficiently operate in the variety of conditions reflective of a large group of patients with this disease."

The research is part of the artificial pancreas project, which is funded by the Juvenile Diabetes Research Foundation and is being conducted by an international group of diabetes research centers. The project's first goal is to integrate an insulin pump and continuous blood glucose monitor to closely replicate a healthy pancreas for patients with type 1 diabetes--patients whose pancreases no longer produce insulin, which is used by the body to control blood glucose levels. An artificial pancreas will allow for tighter and automated control of blood glucose levels, which would significantly help to avoid the long-term complications of the disease.

"This new system will really help streamline the preclinical trials; it will provide data central to the regulatory review process," said investigator Howard Zisser, MD, Director of Clinical Research and Diabetes Technology at the Sansum Diabetes Research Institute in Santa Barbara, CA. "We plan to begin using it in the next several months."

UC Santa Barbara (UCSB) is a leading research institution. The two groups involved in this study at UCSB are the Department of Chemical Engineering, which is committed to excellence in teaching and research and in 2007 was ranked ninth in the United States and second in the University of California by U.S. News and World Report, and its Biomolecular Science and Engineering Program, which offers a unique interdisciplinary approach to graduate training and research spanning Biochemistry, Molecular Biology, Bioengineering and Biomolecular Materials.

Sansum Diabetes Research Institute is a non-profit research center devoted to the prevention, treatment and cure of diabetes through research and education. In particular, it is known for its work on methods to detect and chart the progress of diabetes and its expertise in new diabetes technology.

The OmniPod Insulin Management System is manufactured and sold by Insulet Corporation (Nasdaq: PODD). The FreeStyle Navigator is a product of Abbott Diabetes Care, and the DexCom STS7 is a product of DexCom, Inc.

    Media Contacts:

    Mark Sahl, Lazar Partners
    (609) 992-5205
    msahl@lazarpartners.com

    Tony Rairden
    College of Engineering, UCSB
    (805) 893-4301
    TRairden@Engineering.UCSB.edu


'/>"/>
SOURCE UC Santa Barbara Engineering
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Yale researchers discover mechanism for
2. Three Johns Hopkins researchers named Howard Hughes Medical Institute early career scientists
3. Researchers decipher blood stem cell attachment, communication
4. Researchers studying hearing loss find auditory regions of the brain convert to the sense of touch
5. UIC researchers measure health effects of Chicagos waterways
6. Focus on treating malnutrition in cancer patients, researchers say
7. Researchers Suspect Genetic Link to COPD
8. Syracuse University researchers build a new surface material that resists biofilm growth
9. Researchers Use Gene to End High Blood Sugar in Mice
10. Penn researchers identify new protein important in breast cancer genes role in DNA repair
11. Fish health claims may cause more environmental harm than good: UBC-St. Michaels researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... ... May 27, 2016 , ... Southland Log Homes ... classic American timber frame barn kits, which can be found on its website at ... historic American barn plans, and they highlight the craftsmanship of timber post and beam ...
(Date:5/27/2016)... , ... May 27, 2016 , ... This campaign aims ... stroke, which we as a society can control and change. , As nearly 795,000 ... every 40 seconds within the United States. Plus, with an estimated 129,000 of these ...
(Date:5/27/2016)... New York, NY (PRWEB) , ... May 27, 2016 , ... ... bolstered by inspiring human interest stories, which come courtesy of leaders in the nursing ... within the industry, from leading advocates and associations—namely Abilene Christian University. , As ...
(Date:5/26/2016)... ... , ... W.S. Badger Co. Inc ., the maker of certified organic ... Works Award for its use of effective workplace strategies to increase business and employee ... by the Families and Work Institute (FWI) and the Society for Human Resource Management ...
(Date:5/26/2016)... ... 2016 , ... On Memorial Day, Hope For Heroes and USA ... battle for the country. The nonprofit Hope For Heroes partnered with the leading ... independence for disabled military veterans, as well as police, firemen, and EMS professionals across ...
Breaking Medicine News(10 mins):
(Date:5/30/2016)... 30, 2016 LifeScienceIndustryResearch.com adds ... research report with comprehensive information on the therapeutic ... at various stages, therapeutics assessment by drug target, ... and molecule type, along with latest updates, and ... key players involved in the therapeutic development for ...
(Date:5/27/2016)... LONDON , May 27, 2016 ... an innovative biopharma company focused on the highly ... built a substantial pipeline of potential first-in-class or ... which are in development with strategic partners. HCM,s ... the fast-growing domestic market. We expect progress of ...
(Date:5/26/2016)... -- A key trend that will boost ... new treatments. Cardax, a development stage life sciences company, ... is expected to fulfil large unmet medical needs in ... to develop new treatments for osteoarthritis. One such study ... osteoarthritis are being investigated, and early trials of stem-cell ...
Breaking Medicine Technology: