Navigation Links
Researchers Spot Genes Behind Macular Degeneration
Date:2/24/2012

FRIDAY, Feb. 24 (HealthDay News) -- New research has identified more than 50 genes that can predict age-related macular degeneration, one of the leading causes of blindness worldwide.

Eyes with age-related macular degeneration (AMD) were especially likely to have an overexpression of 20 of these genes, according to researchers from the University of California Santa Barbara (UCSB), the University of Iowa and the University of Utah John Moran Eye Center. Macular degeneration causes a loss of peripheral vision and can lead to blindness.

The study was published in the journal Genome Medicine.

"Not only are these genes able to identify people with clinically recognized AMD and distinguish between different advanced types, some of these genes appear to be associated with preclinical stages of AMD," Dr. Monte Radeke, one of the study's lead authors and an assistant research scientist at UCSB's Center for the Study of Macular Degeneration, said in a journal news release. "This suggests that they may be involved in key processes that drive the disease."

Researchers used a human donor-eye repository to identify differences in gene expression in people with AMD and those with normal eyes. They found that genes expressed below and in the retina, thought to be involved in inflammatory and immune response and wound healing, were overexpressed in eyes with AMD.

Radeke said better understanding of AMD's genetic basis may help in the search for treatments, which currently are very limited.

"Now that we know the identity and function of many of the genes involved in the disease, we can start to look among them to develop new diagnostic methods," he said. "[And we can look] for new targets for the development of treatments for all forms of AMD."

More information

The National Institutes of Health provides more on macular degeneration.

-- Mary Elizabeth Dallas

SOURCE: BioMed Central, news release, Feb. 23, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. 90 percent of firefighters exhibit symptoms of PTSD according to Ben-Gurion University researchers
2. New blood test for early cancer detection developed by Ben-Gurion University researchers
3. UC Davis MIND Institute researchers to present on autism at AAAS Annual Meeting in Vancouver
4. Nasty superbug is being studied by UB researchers
5. Researchers see differences in Autism brain development as early as 6 months
6. As diabetes emerges, researchers track diseases first steps
7. Salk researchers find new drug target for lung cancer
8. GW researchers reveal digital transcriptome of breast cancer
9. PRP treatment aids healing of elbow injuries say researchers
10. Helmet fit critical to preventing concussion, say researchers
11. Rothman at Jefferson researchers show benefits of local anesthesia after knee replacement surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... , ... October 13, 2017 , ... Ellevate Network, the ... business to advocate for action towards gender equality at their inaugural Summit in New ... the globe, and reached a social audience of over 3 million. To watch the ...
(Date:10/13/2017)... ... 2017 , ... Talented host, actor Rob Lowe, is introducing ... new episode of "Success Files," which is an award-winning educational program broadcasted on ... subject in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the ... “America On The Brink” is the creation of published author, William Nowers. Captain ... As a WWII veteran, he spent thirty years in the Navy. Following his ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Planet Fitness, ... the U.S., announced today its plans to open a flagship location in Covington, LA ... the former Rooms To Go store next to Office Depot in the Holiday Square ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical ... Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. ... honor of Morris F. Collen, a pioneer in the field of medical informatics, this ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... , Oct. 12, 2017 West ... in innovative solutions for injectable drug administration, today announced ... the market opens on Thursday, October 26, 2017, and ... results and business expectations at 9:00 a.m. Eastern Time. ... or 253-336-8738 (International). The conference ID is 94093362. ...
(Date:10/11/2017)... CHICAGO , Oct. 11, 2017  Hill-Rom Holdings, ... its Aspen Surgical facility in Las Piedras, ... surgical scalpels and blades. ... confirmed that the facility sustained minor structural damage, temporary ... Hurricane Maria. Repairs have been completed, manufacturing operations have ...
(Date:10/5/2017)... Ill. , Oct. 5, 2017  In ... Association of Oral and Maxillofacial Surgeons (AAOMS) released ... opioids – to be used as a first-line ... pain. Recognizing ... the AAOMS White Paper "Opioid Prescribing: Acute and ...
Breaking Medicine Technology: