Navigation Links
Researchers Report Stem Cell Advance
Date:9/25/2008

Using cold virus to deliver pluripotent cells circumvents safety concerns, scientists say

THURSDAY, Sept. 25 (HealthDay News) -- Researchers report that they have sidestepped a major technical hurdle in the generation of pluripotent stem cells from adult cells.

A team of Boston scientists developed a way to generate induced pluripotent stem cells (iPS) -- which are functionally similar to embryonic stem cells, but which can be produced from adult cells, rather than via the creation or destruction of an embryo -- more safely than ever.

Should the findings, which involved mouse cells, be repeated with humans, they could pave the way for using iPS to delve into the biology of a wide range of genetic diseases. Longer term, they could lead to patient-specific stem-cell therapies.

"I think it's a really important, landmark study," said Kevin Eggan, an assistant professor of Stem Cell and Regenerative Biology and an assistant investigator of the Stowers Medical Institute at Harvard University. He was not involved in the study.

The results were published in the Sept. 25 online edition of Science.

Shinya Yamanaka, of Kyoto University, Japan, first demonstrated in 2006 that adult mouse cells -- for instance, skin cells -- could be reprogrammed into something akin to an embryonic stem cell by the introduction of four specific genes. According to the lead author of this latest study, Matthias Stadtfeld, that "was like a gigantic, essentially quantum leap for biology." The following year, Yamanaka and James Thomson, of the University of Wisconsin, Madison, demonstrated the same approach could create human iPS cells.

Normally, the four genes -- all of which can induce cancer if left unchecked -- are delivered using retroviruses, which integrate their viral DNA into the cells' chromosomes; the worry is that these random insertions will introduce mutations into the cells that would alter their
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. ALS Patients and Researchers Unite in Boston for 4th Annual Leadership Summit
2. OHSU Cancer Institute researchers study breathing during radiation
3. Satellite Healthcare Announces 2008 Norman S. Coplon Extramural Grants : Grants Foster Next-Generation Kidney Disease Researchers
4. New leukemia signal could point way to better treatment, Stanford researchers find
5. Penn researchers use honeybee venom toxin to develop a new tool for studying hypertension
6. Johns Hopkins researchers suppress hunger hormone
7. Penn researchers identify natural tumor suppressor
8. Two U.S. Researchers Win Prestigious International Science Award
9. Researchers receive grant to study ways of preventing heart disease
10. Yerkes researchers create animal model of chronic stress
11. Surgical technique halts cell loss, Parkinsons researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers Report Stem Cell Advance 
(Date:7/11/2014)... Stamford, CT (PRWEB) July 11, 2014 ... – the nation’s only non-profit dedicated exclusively to ... announced that Joshua Corday has joined the organization ... veteran fundraising professional with deep experience securing gifts ... he served as Annual Giving Director for NewYork ...
(Date:7/11/2014)... Global enterprises today are shifting towards the changing ... Managed services offer these global enterprises a strategic method ... into rising operational costs to companies. The aim to ... the global market driver for expanding the managed services ... market is estimated to grow from $142.75 billion in ...
(Date:7/11/2014)... 11, 2014 Presently, disposable medical suppliers ... equipment and supplies segment. During the past two decades, ... growth (on an average 12.5% per year), primarily owing ... Currently, the US is the largest market for disposable ... of 40%. The second position is held by Europe ...
(Date:7/11/2014)... PROVIDENCE, R.I. -- Researchers from The Miriam ... under age 65 have significantly higher rates of ... with mobility impairments were less likely to attempt ... quit-smoking treatments may not be sufficient for this ... online in advance of print in the ...
(Date:7/11/2014)... largest study of its kind has found that ... advantages over their conventional counterparts, including more antioxidants ... study looked at an unprecedented 343 peer-reviewed publications ... and conventional plant-based foods, including fruits, vegetables, and ... to quantify differences between organic and non-organic foods. ...
Breaking Medicine News(10 mins):Health News:Alliance for Cancer Gene Therapy (ACGT) Welcomes Joshua Corday as Senior Development Officer 2Health News:Alliance for Cancer Gene Therapy (ACGT) Welcomes Joshua Corday as Senior Development Officer 3Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 2Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 3Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 4Health News:Global Disposable Medical Supplies Market to See Robust Growth Through Next Decade, According to New TriMark Report Available at MarketPublishers.com 2Health News:Global Disposable Medical Supplies Market to See Robust Growth Through Next Decade, According to New TriMark Report Available at MarketPublishers.com 3Health News:Miriam Hospital study examines smoking prevalence 2Health News:Major study documents nutritional and food safety benefits of organic farming 2Health News:Major study documents nutritional and food safety benefits of organic farming 3
... trips to their GP under a new scheme that has ... The electronic transfer of repeat prescriptions between general practices and ... a bid to streamline the system and make it faster ... down on prescription errors. , And now the scheme is ...
... be much tougher than is typically done, study finds , ... small (1 centimeter or less), certain kinds of breast cancer ... researchers say. , A team at the Mayo Clinic in ... (HER2+) and triple negative (HER2- and ER/PR-) tumors that have ...
... (Oakland, Calif.) The Agency for Healthcare Research and ... Health Research for a study that uses electronic medical ... 175,000 adults to find ways to improve the quality ... which will begin to yield findings next summer, will ...
... Dec. 17 Incisionless surgery is the,most significant ... being,rapidly adopted by a wide variety of academic ... StomaphyX(TM) and EsophyX(TM) procedures already,performed globally. Despite the ... clearance this year, over 50 U.S. centers,have already ...
... babies are born with severe heart defects that must be operated ... odds for these infants are much better now than they were ... be a way to give them an even better chance at ... at handling such cases. , In the first national study of ...
... Find items or activities that stretch youngsters, creativity and ... 16 (HealthDay News) -- When you,re Christmas shopping for ... toys that promote healthy childhood development and reinforce personal ... allow for creativity, imagination, manipulation, and change. If a ...
Cached Medicine News:Health News:Prescription for an electronic revolution? 2Health News:Prescription for an electronic revolution? 3Health News:Even Tiny Breast Tumors May Need Aggressive Treatment 2Health News:Agency for Healthcare Research and Quality funds KP study of electronic records for heart disease 2Health News:EndoGastric Solutions Opens Three Training Centers to Keep Up with Demand from Surgeons Wanting to Learn StomaphyX(TM) Procedures 2Health News:EndoGastric Solutions Opens Three Training Centers to Keep Up with Demand from Surgeons Wanting to Learn StomaphyX(TM) Procedures 3Health News:EndoGastric Solutions Opens Three Training Centers to Keep Up with Demand from Surgeons Wanting to Learn StomaphyX(TM) Procedures 4Health News:For babies with heart defects, death risk is far lower at most experienced hospitals 2Health News:For babies with heart defects, death risk is far lower at most experienced hospitals 3Health News:For babies with heart defects, death risk is far lower at most experienced hospitals 4Health News:Picking the Right Toys Isn't Child's Play 2
(Date:7/11/2014)... July 11, 2014 On ... down 0.52%, the Dow Jones Industrial Average finished the day ... 1,964.68, down 0.41%. The losses were broad based as eight ... S&P 500 Health Care Sector Index ended the day at ... the last one month. Investor-Edge has initiated coverage on the ...
(Date:7/11/2014)... Research and Markets ( http://www.researchandmarkets.com/research/tjlw9k/immunoprotein ) ... Diagnostic Testing Market - Forecasts to 2019: Expected ... and is expected to be valued at USD ... http://photos.prnewswire.com/prnh/20130307/600769 ... segmented according to immunoprotein types which include immunoglobulins, ...
(Date:7/11/2014)... Show organisers report ... Expo 2014 were a brand new audience ... London , plus a 10% increase ...      (Logo: http://photos.prnewswire.com/prnh/20130723/629764-a) ...      (Photo: http://photos.prnewswire.com/prnh/20140711/696892-b ) ...
Breaking Medicine Technology:Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 3UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 4
... 6, 2011 The Female Health Company (NASDAQ-CM: FHCO) ... Industria e Comercio (Semina), was successful in a public ... with up to 20 million FC2 Female Condoms.  The ... quantity purchased will be determined at the Ministry of ...
... InspireMD, Inc. (OTC BB: NSPR) ("Inspire" or the ... system, today announced that Mr. Ofir Paz, InspireMD,s co-founder ... financial officer, will participate in the Benchmark Company, LLC ... The Pfister Hotel, 424 East Wisconsin Ave., Milwaukee, Wis. ...
Cached Medicine Technology:The Female Health Company's Brazilian Distributor, Semina, Awarded Contract For Up To 20 Million FC2 Female Condoms 2The Female Health Company's Brazilian Distributor, Semina, Awarded Contract For Up To 20 Million FC2 Female Condoms 3InspireMD to Participate in Benchmark Company, LLC 2011 One-On-One Investor Conference 2InspireMD to Participate in Benchmark Company, LLC 2011 One-On-One Investor Conference 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: