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Researchers Report Combined Molecules in Red Wine by Far Exceed the Biological Activity of Plain Resveratrol, Consistent With the Composition of Longevinex(R)
Date:3/10/2009

SAN DIMAS, Calif., March 10 /PRNewswire/ -- A recent CBS 60 Minutes TV program drew considerable attention to resveratrol (rez-vair-ah-trawl), a red wine molecule believed to largely be responsible for the French Paradox, the fact the French have far more people living beyond 100 years and exhibit a far lower mortality rate from heart disease than other people living in other developed countries, despite the high-calorie, high-fat diet in France.

(Photo: http://www.newscom.com/cgi-bin/prnh/20080422/LATU004)

Now researchers in Sweden report that the full array of molecules provided in red wine by far exceed the biological effects of plain resveratrol.

The results of the study are consistent with an earlier research study conducted among mice which showed that the combination of resveratrol, quercetin and rice bran phytate-IP6 (Longevinex(R)) exerted a 9-times greater genomic effect than plain resveratrol or a calorie restricted diet. [Experimental Gerontology 2008 Sep; 43(9):859-66]

Researchers instilled various white and resveratrol-rich red wines as well as research-grade resveratrol into lab dishes with various types of cells (brain, lung, colon, cervical, kidney). Surprisingly researchers found the total array of molecules in red wine, but not white wine, produced a far greater biological effect than resveratrol alone. Furthermore, the beneficial effects were produced independently from alcohol or activation of the Sirtuin1 gene, considered a survival and longevity gene.

Only at higher concentrations did resveratrol cause unhealthy cells to die off (21%), compared to untreated cells (6%). Such a high concentration may produce long-term side effects in humans. But within 24 hours, red wine abolished virtually all (100%) the unhealthy cells. Red wine exerted its effect by disarming protective
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SOURCE Longevinex
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