Navigation Links
Researchers Publish Genome Sequence for Duck-Billed Platypus
Date:5/7/2008

One of the few mammals that lays eggs offers clues to evolution of all mammalian genes

WEDNESDAY, May 7 (HealthDay News) -- An international team of scientists has published the first analysis of the genome sequence of the duck-billed platypus, one of the few mammals that lays eggs.

The research offers clues about how genomes were organized during the early evolution of mammals.

"At first glance, the platypus appears as if it was the result of an evolutionary accident. But as weird as this animal looks, its genome sequence is priceless for understanding how fundamental mammalian biological processes have evolved. Comparisons of the platypus genome to those of other mammals will provide new insights into the history, structure and function of our own genome," Francis S. Collins, director of the U.S. National Human Genome Research Institute (NHGRI), said in a prepared statement.

The NHGRI helped fund the analysis of the genome sequence of the platypus, which is native to Australia and has many unique characteristics. Along with being one of the few mammals that lays eggs, the platypus has a duck-like bill, an electrosensory system it uses to forage for food underwater, and a thick fur coat adapted for icy waters. Males have hind leg spurs that can deliver venom that causes excruciating pain.

The researchers found that the platypus genome contains about the same number of protein-coding genes as other mammals (approximately 18,500) and also shares more than 80 percent of its genes with other mammals whose genomes have been sequenced.

The scientists then looked for unique parts of the platypus genome that have been lost from mammalian genomes, as well as genetic features associated with reptiles.

"The mix of reptilian, mammalian, and unique characteristics of the platypus genome provides many clues to the function and evolution of all mammalian genomes," study senior author Richard K. Wilson, director of Washington University School of Medicine's Genome Sequencing Center, said in a prepared statement. "Now, we'll be able to pinpoint genes that have been conserved throughout evolution, as well as those that have been lost or gained."

The research was published in the May 8 issue of the journal Nature.

"This genome provides a unique perspective on what the genomes of our earliest mammalian ancestors may have looked like. It is fascinating that what we think of as being reptile-like (i.e., egg laying and venom) and mammal-like features can co-exist in the same genome," Adam Felsenfeld, head of the Comparative and Sequencing Analysis Program in NHGRI's Division of Extramural Research, said in a prepared statement.

More information

The NHGRI has more about genomics.



-- Robert Preidt



SOURCE: U.S. National Human Genome Research Institute, news release, May 7, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. UC San Diego researchers target tumors with tiny nanoworms
2. Researchers Find Lubricant Doesnt Hinder Fertility
3. MGH researchers report successful new laser treatment for vocal-cord cancer
4. Stanford researchers synthesize compound to flush HIV out of hiding
5. World first: researchers develop completely automated anesthesia system
6. Researchers Develop Quick Way to Create Human Antibodies
7. Researchers Tackle HIV From a New Angle
8. Researchers important markers of high risk of type 2 diabetes
9. Cancer researchers receive NIH grant to advance brain tumor therapies from lab to clinical trials
10. Researchers Identify Contaminant in Tainted Heparin
11. UMass Medical School researchers awarded pediatric HIV vaccine development grant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... ... May 26, 2016 , ... Metcalf & Associates’ ... years of experience in leading technology and human resources operations for health care, ... Morrow-Fox will be featured on Metcalf’s VoiceAmerica radio show , Innovative Leaders ...
(Date:5/26/2016)... ... May 26, 2016 , ... Dr. LeRoy Perry’s recently authored whitepaper, ... mobile devices on the billions of users, hundreds of millions of whom are coming ... life threatening, the frequent and common action of looking down at hand-held technology devices ...
(Date:5/26/2016)... ... May 26, 2016 , ... Development Team of Pixel Film Studios ... , "This new layered style transition tool will keep a consistent flow to your ... Pixel Film Studios. , TranSweep is an all new layered style transition tool ...
(Date:5/26/2016)... ON (PRWEB) , ... May 26, 2016 , ... ... Organization, is proud to announce that it has successfully completed another Health Canada ... Branch Inspectorate of Health Canada. The rating resulted from a Good Manufacturing Practices ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... weekend to host their second pop-up shop for three consecutive weekends. The pop-up ... to the Santa Barbara community, a community full of women who appreciate the ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... Zealand , May 24, 2016 ... informatics solutions for the healthcare sector, has been named the ... Zealand Hi-Tech Awards 2016. Dr Bruce Davey ... acknowledgement for our team.  It,s really good to be recognised ... healthcare internationally. Our products are used in 35 countries around ...
(Date:5/24/2016)... , May 24, 2016 Celsion ... drug development company, today provided an update on ... escalating clinical trial combining GEN-1, the Company,s DNA-based ... treatment of newly-diagnosed patients with advanced ovarian cancer ... debulking surgery.  GEN-1 is an IL-12 DNA plasmid ...
(Date:5/24/2016)... 2016 The innovator of ... , s first dual therapy stent, introduces catheters ... OrbusNeich, a global company specializing in the provision ... include products to treat peripheral artery disease. The JADE™ ... devices for lower limb and arteriovenous (AV) fistula intervention. ...
Breaking Medicine Technology: