Navigation Links
Researchers Make Stem Cells That Secrete Insulin
Date:2/20/2008

Mouse study suggests it could help control diabetes in humans

WEDNESDAY, Feb. 20 (HealthDay News) -- Scientists have found a way to convert human embryonic stem (ES) cells into cells that release insulin in response to glucose and ease a diabetes-like condition in mice, a new study says.

Further research and development of this technique could lead to a renewable source of cells for treatment of people with diabetes, according to Emmanuel Baetge, of Novocell Inc., in San Diego, and colleagues, who published their work online in the current issue of Nature Biotechnology.

Type 1 and some forms of type 2 diabetes involve the loss of pancreatic beta cells, which regulate blood glucose (sugar) levels by releasing insulin, according to background information in a news release about the study.

In previous work, Baetge and the team were able to coax human ES cells part of the way toward becoming beta cells, but not far enough for them to carry out the key function of mature beta cells, which is the release of insulin in response to glucose.

In this new study, the researchers transplanted immature beta cells derived from human ES cells into mice whose beta cells had been destroyed by chemical treatment. After one to three months, the transplanted cells developed into glucose-responsive, insulin-secreting cells and helped control blood glucose levels in the mice.

Previous research demonstrated that transplantation of pancreatic beta cells (within islets) can help control diabetes in humans. But the therapy relies on cells from donor pancreases, meaning that the supply of such cells is limited. That's why scientists are trying to develop alternative sources of beta cells, such as those derived from human ES cells.

More information

The American Diabetes Association has more about islet transplantation.



-- Robert Preidt



SOURCE: Nature Biotechnology, news release, Feb. 20, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. U of M researchers determine structure of protein that mutates DNA of the AIDS virus HIV-1
2. Researchers create first chikungunya animal model
3. Researchers aim to prevent global prematurity and stillbirths
4. Researchers Aim to Prevent Global Prematurity and Stillbirths
5. UH researchers study Hispanic childrens activities, views on places to play
6. Researchers discover new way to reverse poor circulation and heal wounds
7. Bacterial toxin closes gate on immune response, Penn researchers discover
8. UD researchers discover technique for repairing gene defect that causes spinal muscular atrophy
9. Veterinary researchers study poultry virus as human cancer treatment
10. UD researchers discover promising technique for repairing gene that causes spinal muscular atrophy
11. Researchers at BMC find disability does not necessarily follow disease in living to old age
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers Make Stem Cells That Secrete Insulin
(Date:2/27/2017)... CA (PRWEB) , ... February 27, 2017 , ... ... for hair transplantation therapy, is proud to announce a new informational post on ... therapy procedures. Follicular Unit Extraction (FUE) hair transplant and Follicular Unit Transplantation (FUT) ...
(Date:2/27/2017)... Morristown, New Jersey (PRWEB) , ... February 27, 2017 , ... ... the highest cancer rates, among all types and genders. And the need for advanced ... led by RWJ and its top-rated cancer care program, in collaboration with their non-profit ...
(Date:2/26/2017)... ... 2017 , ... Today, A' Design Awards & Competition has ... Design Awards. , The 7th A' Social Design Award is open for ... with realized projects and conceptual works. , The first phase of the International ...
(Date:2/26/2017)... ... February 26, 2017 , ... NuevaCare, a leading home care agency based ... and Palo Alto, is proud to announce an important upgrade to its geographic information ... home care close to home, and by having city-specific pages, NuevaCare is answering that ...
(Date:2/26/2017)... ... February 26, 2017 , ... IndustryArchive.Org . is announcing a new ... B2B Sellers will now only pay for B.A.N.T. quality sales leads based on the ... said, “Given the new reality that B2B buyers are controlling the sales process via ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... CUPERTINO, Calif. , Feb. 24, 2017  In ... fourth quarter 2016 financial results press release, you are ... be broadcast live over the internet on Tuesday, March ... Pacific Time). A live audio webcast of ... at www.durect.com and clicking "Investor Relations."  If ...
(Date:2/24/2017)... 2017 Report analyzes the worldwide markets for Endodontic ... for the US, Canada , ... Asia-Pacific , Latin America , and ... the period 2015 through 2022. Also, a six-year historic analysis ... derived from primary and secondary research. Company profiles are primarily ...
(Date:2/24/2017)... Feb. 23, 2017  This report analyzes the worldwide ... following Products: Intermediates, Analytical, and Others. ... include Pharmaceuticals, and Agrochemicals. The report provides separate comprehensive ... Europe , and Rest of World. ... 2015 through 2022. Also, a six-year historic analysis is ...
Breaking Medicine Technology: