Navigation Links
Researchers Identify New Method to Selectively Kill Metastatic Melanoma Cells
Date:8/3/2009

or mda-5, a gene initially cloned in Fisher's laboratory, that activates a protein called NOXA that is involved with programmed cell death. This series of chemical reactions results in induction of a cell-killing process involving self-digestion that leads to programmed cell death specifically in melanoma cells. Fisher said that mda-5 is a key regulator of innate immunity that induces interferon beta production limiting replication of specific pathogenic viruses.

This work was supported by grants from the National Institutes of Health, the Spanish Ministry of Science and Innovation, the Spanish Association Against Cancer and the Spanish National Cancer Research Center.

The project team in Spain was led by Soengas, with the Melanoma Laboratory, Molecular Pathology Program, Spanish National Cancer Research Center, Madrid, Spain. Fisher, who also is professor and chair of the Department of Human and Molecular Genetics, and director of the VCU Institute of Molecular Medicine in the VCU School of Medicine, lead the investigative team at VCU which included Paola M. Barral, Ph.D., assistant professor in the Department of Human and Molecular Genetics; and Rupesh Dash, Ph.D., postdoctoral research scientist, in the Department of Human and Molecular Genetics, and the VCU Institute of Molecular Medicine.

EDITOR'S NOTE: A copy of the study is available for reporters by email request from the Cell Press communications office: cgenova (at) cell (dot) com.

About the VCU Massey Cancer Center: The VCU Massey Cancer Center is one of 65 National Cancer Institute-designated institutions that leads and shapes America's cancer research efforts. Working with all kinds of cancers, the Center conducts basic, translational and clinical cancer research, provides state-of-the-art treatments and clinical trials, and pr
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine news :

1. Researchers identify new method to selectively kill metastatic melanoma cells
2. Researchers effectively treat tumors with use of nanotubes
3. Fox Chase researchers identify differences in treatments and outcomes of patients with second primary lung cancers versus those with one primary lung cancer
4. Researchers Discover the Tale Behind Short Dogs
5. Higher drug doses needed to defeat tuberculosis, UT Southwestern researchers report
6. Mayo researchers find anesthesia not harmful for babies during birth process
7. Mayo Researchers Find Anesthesia Not Harmful for Babies During Birth Process
8. Pinpointing cause of colic: UT Houston researchers identify organism
9. Zucker Hillside Researchers to Receive Large Federal Grant to Test for the Early Treatment of Schizophrenia
10. Researchers find that eating high levels of fructose impairs memory in rats
11. Ben-Gurion U. researchers identify how stressed fat tissue malfunctions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... Angeles, CA (PRWEB) May 22, 2013 Many ... a great deal of pain for a patient if left ... that their pain could be easily fixed through occlusal adjustment. ... teeth, or neck and back pain should have their dentist ... can change the bite and can lead to problems if ...
(Date:5/22/2013)... is available in German . ... Research Foundation) is establishing 11 new Research Training Groups ... decision was made by the relevant Grants Committee in ... awarded to the new programmes for an initial period ... the 11 new Research Training Groups, the Grants Committee ...
(Date:5/22/2013)... Hopkins researchers have developed new guidelines the first ... amount of blood ordered for surgical patients. The recommendations, ... The Johns Hopkins Hospital (JHH), can potentially save the ... patient safety, researchers say. , A report on the ... online in the journal Anesthesiology , suggests millions ...
(Date:5/22/2013)... Ethos Spa Skin and Laser Center , has ... lifestyle of the modern man and woman. All customers have ... whether it is for an anniversary or birthday present, a ... , Clients should know that they have a wide selection ... the Ethos Spa’s website, ranging from abstract artistic drawings to ...
(Date:5/22/2013)... May 22, 2013 Beginning Aug. 22, ... the Conrad Foundation’s Spirit of Innovation Challenge . ... plan competition, free and open to students ages 13 ... Spirit of Innovation Challenge celebrates the life and entrepreneurial ... on the Moon. The program challenges teens to work ...
Breaking Medicine News(10 mins):Health News:Dr. Martin N. Gorman: Make Headaches, Sensitive Teeth and Neck or Back Pain a Thing of the Past 2Health News:DFG establishes 11 new research training groups 2Health News:DFG establishes 11 new research training groups 3Health News:DFG establishes 11 new research training groups 4Health News:DFG establishes 11 new research training groups 5Health News:Johns Hopkins rewrites obsolete blood-ordering rules 2Health News:Johns Hopkins rewrites obsolete blood-ordering rules 3Health News:Ethos Spa Skin And Laser Center Has Launched Their Customizable Gift Certificates 2Health News:Conrad Foundation Announces 2013-2014 Spirit of Innovation Challenge Launch Date 2
... , FRIDAY, Jan. 20 (HealthDay News) -- Rapid ... with an increased risk of asthma symptoms in preschool children, ... infancy might be a critical period for the development of ... Netherlands. They examined data collected from 5,125 children who ...
... non-intubated,patients may be an effective strategy for bridging patients ... Germany. "As waiting times for donor organs continue ... for patients with end-stage lung disease awaiting transplantation," said ... Hannover Medical School in Hannover, Germany. "Our study shows ...
... Shortages of key drugs used to fight infections represent ... risk, according to a review published in Clinical ... anti-infective shortages can substantially alter clinical care and may ... development of new anti-infectives has slowed and the prevalence ...
... , THURSDAY, Jan. 19 (HealthDay News) -- Allowing homeless ... were provided with housing actually decreased their heavy drinking by ... found. The study, published in the Jan. 19 issue ... included residents of a program called project-based Housing First, which ...
... aggressive and spread they are the most deadly. Unfortunately, ... A new imaging platform developed by Lawson Health Research ... insight into just that - the exact moment when ... E-cadherin, are important for the maintenance of normal tissue ...
... With a growing need for family-friendly workplace policies, ... Women & Families, with support from the Rockefeller Foundation, ... to positive economic outcomes for working families, businesses and ... for Women and Work at Rutgers, the State University ...
Cached Medicine News:Health News:Rapid Infant Growth Linked to Asthma in Study 2Health News:Extracorporeal membrane oxygenation as a bridge to lung transplantation 2Health News:Anti-infective drug shortages pose threat to public health and patient care 2Health News:Alcohol OK in Housing for Formerly Homeless, Study Says 2Health News:Lawson researchers engineer a switch to tame aggressive cancers 2Health News:Rutgers study finds paid family leave leads to positive economic outcomes 2Health News:Rutgers study finds paid family leave leads to positive economic outcomes 3
(Date:5/22/2013)... May 22, 2013 Hemoglobin A1C levels ... with Type 2 diabetes, while modest improvements in ... outcomes and can lead to substantial healthcare cost ... International Society for Pharmacoeconomics and Outcomes Research (ISPOR) ... studies, sponsored by Valeritas, makers of the V-Go ...
(Date:5/22/2013)... , May 22, 2013  Generex Biotechnology Corporation ... demonstrating the superiority of the AE37 breast cancer vaccine ... ( www.antigenexpress.com ). The presentations will be made at ... Oncology (ASCO) to be held in Chicago ... The presentation entitled " Booster inoculations of ...
(Date:5/22/2013)...  Flagship Ventures, a leading venture capital and ... today announced the appointment of Stephane ... this role, Mr. Bancel will provide strategic counsel ... addition to working closely with companies in the ... and Chief Executive Officer of Moderna Therapeutics, a ...
Breaking Medicine Technology:Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 2Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 3Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 4Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 5Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 6Generex Announces ASCO Presentations on the Antigen Express Advanced Stage AE37 Cancer Vaccine 2Generex Announces ASCO Presentations on the Antigen Express Advanced Stage AE37 Cancer Vaccine 3Generex Announces ASCO Presentations on the Antigen Express Advanced Stage AE37 Cancer Vaccine 4Life Science Industry Veteran Stephane Bancel Joins Flagship Ventures 2Life Science Industry Veteran Stephane Bancel Joins Flagship Ventures 3
... Administration Control System, provides the healthcare ... are administering the correct medication to ... bar coded patient bracelet and a ... of the hospital's pharmacy system to ...
... administration, any error is one you simply ... the Dynamic Hospital AdministratOR. This powerful application ... suitable for hospitals of all sizes. It ... as a fully-integrated component of existing systems. ...
... that support the nursing process. The caregiver ... I&O information at the point of collection ... This design supports compliance with documentation requirements., ... at the nursing station, wCareAssist™ is right ...
... critical information to the patient's unique bar-coded identifier for accurate, easy recording of tests, diagnosis and care. ... ... ... Patient LinkUp™ Enterprise (PLUE) ...
Medicine Products: