Navigation Links
Researchers Identify Genes Tied to Breast Cancer that Spreads to the Brain
Date:9/20/2013

Chicago (PRWEB) September 20, 2013

Researchers have identified the epigenetic markers that determine whether breast cancer will spread to the brain, which could lead to earlier diagnoses and more effective treatment, suggests a study being presented today at ASCP 2013 Chicago, the annual meeting of the American Society for Clinical Pathology.

Breast cancer is the leading cause of cancer and the second most common cause of cancer death among U.S. women, according to the Centers for Disease Control and Prevention (CDC). Some breast cancers are more likely to spread beyond the breast (metastasize), including to the brain. Currently, doctors don’t have a clear picture at diagnosis regarding which breast cancers are likely to metastasize to the brain and which are not. Encouragingly, researchers have recently identified molecular markers called micro ribonucleic acids (RNAs) as potentially playing a role.

“Survival rates are low once breast cancer metastasizes to the brain,” said Seema Sethi, MD, a resident at Wayne State University and Detroit Medical Center, and lead author of the study. “This research will help us develop targeted therapies so we can more aggressively treat patients with this form of breast cancer.”

Researchers extracted micro RNA from the tumors of 90 women with breast cancer, including 45 whose cancer had spread to the brain (metastasized) and 45 whose cancer had not. After analyzing the data, researchers found that several micro RNAs were significantly altered in patients whose breast cancer had spread to the brain. They also identified several target genes involved in the process.

Researchers believe these micro RNAs and their target genes could help identify which breast cancers eventually will metastasize to the brain when the cancer is first diagnosed and determine the course of therapy, including how aggressive treatment should be. This newer approach, called personalized medicine, means targeted therapies and specific treatment options would be available depending on each patient’s medical history and epigenetic markers.

# # # # #

ASCP 2013 Chicago will be held at the Hyatt Regency Chicago, 151 E. Upper Wacker Dr., in Chicago. For more information about the meeting, visit http://www.ascp.org/ascp2013.

About the American Society for Clinical Pathology
Founded in 1922 in Chicago, ASCP is a medical professional society with more than 100,000 member board-certified anatomic and clinical pathologists, pathology residents and fellows, laboratory professionals, and students. ASCP provides excellence in education, certification, and advocacy on behalf of patients, pathologists, and laboratory professionals. For more information, visit http://www.ascp.org.

Read the full story at http://www.prweb.com/releases/2013/9/prweb11145625.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. UC Davis Researchers Find How Viral Infection Disrupts Neural Development in Offspring, Increasing Risk of Autism
2. IOActive Ramps Up Recruitment for Top Security Researchers and Consultants in South America
3. UI researchers: Bracing is effective in adolescents with idiopathic scoliosis
4. CWRU researchers find what stresses parents with a chronically ill child
5. Yale researchers see decline in hospitalizations for serious heart infection
6. Researchers identify novel biomarker for diabetes risk
7. Tufts researchers identify how Yersinia spreads within infected organs
8. Approved cancer drug potentially could help treat diabetes, Stanford researchers find
9. Mount Sinai Researchers Show Stem Cells Are Wired for Cooperation, Down to the DNA
10. Virginia Tech Carilion researchers find surprising relationships in brain signaling
11. Researchers to identify genetic biomarkers for aggressive breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa ... contributed a medical article to the newly revamped Cosmetic Town journal ... the hair transplant procedure known as Follicular Unit Extraction (FUE). , ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Leading pediatric ... peers in Washington, D.C., for the 49th Congress of the International Society of ... Vice President of the Center for Cancer and Blood Disorders at Children’s ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... one of Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. ... awards program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at ...
(Date:10/12/2017)... ... October 12, 2017 , ... In the United States, ... In some states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the ... have extremely low property-tax rates, which contributes to the relatively lower cost of ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... at the University of California Berkeley, and other leading institutions in announcing the ... power of institutions to change the way animals are raised for food. , ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... -- Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today provided an ... Puerto Rico , where the company ... Following a comprehensive onsite assessment, ... damage, temporary loss of power and minimal water damage ... operations have resumed, and the company expects to return ...
(Date:10/7/2017)... Oct. 6, 2017   Provista, a proven ... $100 billion in purchasing power, today announced a new ... The Newsroom is the online home for ... infographics, expert bios, news releases, slideshows and events. ... a wealth of resources at their fingertips, viewers can ...
(Date:10/4/2017)... , Oct. 4, 2017  According to the Centers for Disease Control ... of October . PhysicianOne Urgent Care is helping communities across ... NY , by offering no-cost* flu shots through the end of ... by certain health insurance regulations. ... best time to get a flu shot is by the end of ...
Breaking Medicine Technology: