Navigation Links
Researchers Identify Genes Tied to Breast Cancer that Spreads to the Brain
Date:9/20/2013

Chicago (PRWEB) September 20, 2013

Researchers have identified the epigenetic markers that determine whether breast cancer will spread to the brain, which could lead to earlier diagnoses and more effective treatment, suggests a study being presented today at ASCP 2013 Chicago, the annual meeting of the American Society for Clinical Pathology.

Breast cancer is the leading cause of cancer and the second most common cause of cancer death among U.S. women, according to the Centers for Disease Control and Prevention (CDC). Some breast cancers are more likely to spread beyond the breast (metastasize), including to the brain. Currently, doctors don’t have a clear picture at diagnosis regarding which breast cancers are likely to metastasize to the brain and which are not. Encouragingly, researchers have recently identified molecular markers called micro ribonucleic acids (RNAs) as potentially playing a role.

“Survival rates are low once breast cancer metastasizes to the brain,” said Seema Sethi, MD, a resident at Wayne State University and Detroit Medical Center, and lead author of the study. “This research will help us develop targeted therapies so we can more aggressively treat patients with this form of breast cancer.”

Researchers extracted micro RNA from the tumors of 90 women with breast cancer, including 45 whose cancer had spread to the brain (metastasized) and 45 whose cancer had not. After analyzing the data, researchers found that several micro RNAs were significantly altered in patients whose breast cancer had spread to the brain. They also identified several target genes involved in the process.

Researchers believe these micro RNAs and their target genes could help identify which breast cancers eventually will metastasize to the brain when the cancer is first diagnosed and determine the course of therapy, including how aggressive treatment should be. This newer approach, called personalized medicine, means targeted therapies and specific treatment options would be available depending on each patient’s medical history and epigenetic markers.

# # # # #

ASCP 2013 Chicago will be held at the Hyatt Regency Chicago, 151 E. Upper Wacker Dr., in Chicago. For more information about the meeting, visit http://www.ascp.org/ascp2013.

About the American Society for Clinical Pathology
Founded in 1922 in Chicago, ASCP is a medical professional society with more than 100,000 member board-certified anatomic and clinical pathologists, pathology residents and fellows, laboratory professionals, and students. ASCP provides excellence in education, certification, and advocacy on behalf of patients, pathologists, and laboratory professionals. For more information, visit http://www.ascp.org.

Read the full story at http://www.prweb.com/releases/2013/9/prweb11145625.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. UC Davis Researchers Find How Viral Infection Disrupts Neural Development in Offspring, Increasing Risk of Autism
2. IOActive Ramps Up Recruitment for Top Security Researchers and Consultants in South America
3. UI researchers: Bracing is effective in adolescents with idiopathic scoliosis
4. CWRU researchers find what stresses parents with a chronically ill child
5. Yale researchers see decline in hospitalizations for serious heart infection
6. Researchers identify novel biomarker for diabetes risk
7. Tufts researchers identify how Yersinia spreads within infected organs
8. Approved cancer drug potentially could help treat diabetes, Stanford researchers find
9. Mount Sinai Researchers Show Stem Cells Are Wired for Cooperation, Down to the DNA
10. Virginia Tech Carilion researchers find surprising relationships in brain signaling
11. Researchers to identify genetic biomarkers for aggressive breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... California (PRWEB) , ... May 26, 2016 , ... ... associated with discovery of thousands of defective respirators, according to court documents and ... the case of William and Becky Tyler v. American Optical Corporation, Case No. ...
(Date:5/26/2016)... , ... May 26, 2016 , ... On Memorial Day, ... women who lost their lives in military battle for the country. The nonprofit ... 2015 to provide more programs that empower independence for disabled military veterans, as well ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... MadgeTech will ... designed, engineered, and manufactured in Warner, New Hampshire at the MadgeTech headquarters. With products ... reliable monitoring solutions trusted by government agencies, including NASA. , In 2012, NASA ...
(Date:5/26/2016)... ... ... In an effort to provide hair restoration information to the widest possible audience, Dr. Parsa ... not use the app. Dr. Mohebi, the founder of Parsa Mohebi Hair Restoration, is making ... , Dr. Mohebi says, “The positive response to the Snapchat videos we started last month ...
(Date:5/26/2016)... Tampa, Fla. (PRWEB) , ... May 26, 2016 , ... ... Center (AHEC) to host a six-week smoking cessation class starting June 6 at their ... AHEC’s website, http://www.gnahec.org . , Additionally, the Lung Institute has created a free ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... Germany and GERMANTOWN, Maryland , ... QGEN ; Frankfurt Prime Standard: QIA) today announced ... agreement with Therawis Diagnostics GmbH to develop and commercialize predictive ... and market PITX2 as a marker to predict effectiveness of ... patients. "We are pleased to partner with Therawis, ...
(Date:5/25/2016)... 25, 2016 As illustrated by ... this month, the numbers and momentum of cannabis in ... into the billions, more research and development push the ... State of Legal Marijuana Markets Report  from from ArcView ... much of the increase in sector is attributed to ...
(Date:5/25/2016)... England , May 25, 2016 ... company employing the precision of circulating tumour DNA ... today announces the appointment of Professor Clive ... provide medical leadership across the clinical development programme, ... Inivata,s products help deliver significant improvements in clinical ...
Breaking Medicine Technology: