Navigation Links
Researchers Identify 2 Genes Linked to Fatty Liver Disease
Date:3/24/2010

hibits an enzyme that breaks down fats, Shulman said. The excess fats are deposited in the liver. Thirty-eight percent of the men with the gene variants had fatty liver disease.

The Yale group then did the same genetic study in a mixed ethnic group of 163 men and found a similar incidence of fatty liver disease and insulin resistance among those with the gene variants.

The next step in the Yale program will be an effort to learn why the condition is more common in East Asian men, Shulman said. But a longer-term goal is to put the finding to use to detect high-risk individuals, he noted.

"If you have a test, you can make them careful about their weight," he said. "The good news is that we have shown that even modest weight reduction can reduce the risk. Dropping 15 pounds reverses fatty liver disease and insulin resistance."

Beyond that would be a treatment aimed at the gene variants, Shulman said. "It's even better if you have something you can do about it," he said. "You could screen people, test for fatty liver and insulin resistance and treat that with agents."

A screening test could help single out people whose fatty livers were not dangerous, said Dr. Anna Mae Diehl, chief of gastroenterology at Duke University, who wrote an accompanying editorial in the journal.

"Simply having extra fat in the liver is of unknown significance," Diehl said. "Many people who have it are fine. Some get more advanced forms of liver disease. We want to know if this polymorphism is associated not only with fat, but also with damage."

Such a determination now requires a biopsy to remove a segment of the liver for examination, Diehl said. "We still don't have a noninvasive blood test," she said. "That might help sort out who has more serious damage. We are hoping that in the next few years better tests become available."

More information

To learn more about fatty liver disease, visit the <
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. NIA researchers find gene to explain mouse embryonic stem cell immortality
2. Researchers discover fundamental step in immune-system development
3. Scott & White Healthcare researchers studying investigational agent that targets breast cancer
4. SRI International Researchers to Present Work on Early Detection Tool for Neglected Tropical Diseases at 2010 American Chemical Society (ACS) Meeting
5. Researchers find new chemotherapy combination shows promise in endometrial cancer
6. Researchers ID brain abnormalities in children exposed to methamphetamine in utero
7. Mount Sinai researchers are the first to identify heart abnormalities in World Trade Center workers
8. Researchers discover chemical that may protect hearts of muscular dystrophy patients
9. Researchers recommend curriculum on unhealthy substance use
10. Using new approach, Mayo Clinic researchers find level of gene alters risk of Alzheimers disease
11. Researchers discover brain tumors grow-or-go switch
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... 2014 The regional economy is about ... is on the grow again. The plant will ... 2016 to boost production of the popular Highlander midsize ... overall investment to $4 billion. This step allows Toyota ... additional flexibility to adjust its product mix to meet ...
(Date:8/22/2014)... Americans know little about how Ebola is transmitted and harbor ... United States, a new survey shows. About four in ... a major Ebola outbreak in the United States, and one-quarter ... get sick with the deadly virus in the next year, ... However, those opinions don,t match reality, the Harvard researchers ...
(Date:8/22/2014)... Las Vegas, NV (PRWEB) August 22, 2014 ... that teaches readers how they can use natural methods ... for years has caught the attention of Shane Michaels, ... only a condition that affects the skin, it can ... suffer from it,” reports Michaels. “The intense itching and ...
(Date:8/22/2014)... Epidermal growth factor receptor (EGFR) mutations found in ... of advanced non-small cell lung cancer (NSCLC) patients correlates ... DNA. , EGFR tyrosine kinase inhibitor (TKI) therapy is ... NSCLC, but the standard for determining mutation status is ... be limited or not available. A more abundant and ...
(Date:8/22/2014)... August 22, 2014 Advancements in ... some clinical applications due to their cost-effectiveness, non-invasiveness, ... innovations in ultrasound, such as the evolution of ... to keep the market moving throughout 2014 and ... can enhance not only the point-of-care (POC) testing ...
Breaking Medicine News(10 mins):Health News:Toyota Indiana Adding 300 Jobs to Build More Highlanders 2Health News:Many Americans Harbor Unfounded Fears About Ebola Outbreak: Survey 2Health News:Beat Eczema: Review Exposes Susan Clark’s Guide to Curing Eczema Naturally 2Health News:High concordance between EGFR mutations from circulating-free tumor DNA and tumor tissue in non-small cell lung cancer 2Health News:Global Top Ultrasound Market Suppliers Assessed in New VPG Research Report Available at MarketPublishers.com 2Health News:Global Top Ultrasound Market Suppliers Assessed in New VPG Research Report Available at MarketPublishers.com 3
... FAIRFAX, Va., Sept. 18 The American Society,for Therapeutic ... growing staff; Barbara Muth is ASTRO,s new director of ... policy analyst., Ms. Muth brings nearly 20 years ... she worked with the American Red Cross for,eight years ...
... HOUSTON, Sept. 18 Today US Oncology, Inc., ... network,announced the appointment of Michael A. Sicuro as ... position Sicuro will lead and manage,the finance function ... financial,analytical, operational, and transactional issues, including accounting,financial reporting, ...
... claim that internationally adopted children can undergo puberty at ... variety of health risks as adults: abdominal obesity, hypertension, ... are internationally adopted children really more at risk? , ... their living conditions up until their adoption," says Hlne ...
... complication of severe burns. Injury to GI function, ... initiator as well as a stimulator for occurrence ... organ dysfunction syndrome following severe burns. With the ... the stereotype of clinical treatment in recent 30 ...
... present brief clinical report showed that Contrast-enhanced ... agent, Sonazoid, can allow surgeons to investigate ... to find new metastases intraoperatively. , ,Contrast-enhanced ... conventional IOUS to identify new occult lesions ...
... an essential role in filling the gap of transplants ... Considering that living related donors are healthy individuals at ... return to quality of life. , A research article ... World Journal of Gastroenterology addresses this question. ...
Cached Medicine News:Health News:ASTRO Names New Research Director, Health Policy Analyst 2Health News:US Oncology Appoints Michael A. Sicuro Executive Vice President and Chief Financial Officer 2Health News:Strategies for preventing gastrointestinal complications in severely burned patients 2Health News:An analysis of the surgical and perioperative complications in right hepatectomies 2
(Date:8/21/2014)...  Vermillion, Inc. (NASDAQ: VRML ), a ... health, has appointed Holly B. Bauzon as ... Ms. Bauzon has a proven track record in both ... services companies. She has more than 20 years of ... held the position of Director, Lab Services Sales and ...
(Date:8/21/2014)... YORK , Aug. 21, 2014  Publicis Groupe ... Shannon Hartley , Managing Partner and Healthcare Industry Group ... PharmaVoice 100, which recognizes the most inspiring people in ... are leaders in research and development, marketing, technology, creativity, ... agency in 2006 as a partner in its leading ...
(Date:8/21/2014)... 2014 /PRNewswire-iReach/ -- Inc. magazine today ... third straight year, No. 349 in Health on ... of the nation,s fastest-growing private companies. The list ... important segment of the economy—America,s independent entrepreneurs. Companies ... LinkedIn, Zillow, and many other well-known names gained ...
Breaking Medicine Technology:Vermillion Appoints Holly B. Bauzon as VP of Sales and Managed Markets 2Shannon Hartley Shines in PharmaVOICE 100 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3
... 2, 2010 BioMarin Pharmaceutical Inc. (Nasdaq: BMRN ... Agency (MHRA) in the UK has completed review of the ... acceptance for BMN 673 for genetically-defined cancers.  The company expects ... of 2011. "BMN 673 has been proven to ...
... THOUSAND OAKS, Calif., Dec. 2, 2010 Amgen (Nasdaq: ... from several key Nplate® (romiplostim) studies at the 52nd Annual ... Dec. 4-7, 2010, in Orlando, Fla. Results from six studies ... purpura (ITP) add to the growing body of data supporting ...
Cached Medicine Technology:MHRA Completes Review of CTA and Issues Notice of Acceptance for BMN 673 for Genetically-Defined Cancers 2MHRA Completes Review of CTA and Issues Notice of Acceptance for BMN 673 for Genetically-Defined Cancers 3Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 2Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 3Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 4Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 5Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 6Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 7Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 8Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 9Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 10Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 11Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 12Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 13Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 14Amgen Highlights Data to Be Presented at American Society of Hematology Annual Meeting 15
Used to introduce large devices for vascular intervention....
Used for the introduction of catheters, balloons and other vascular devices....
Used to introduce balloon, closed and non-tapered end catheters or other devices for intervention....
Sheath Introducer featuring patented SLIX Valve, rotating collar, kink-resistant cannula and atraumatic tip transitions....
Medicine Products: