Navigation Links
Researchers ID Suite of Genes in Aging Process
Date:11/19/2008

Biomarkers could provide scientific baseline for anti-aging drug trials, study says

WEDNESDAY, Nov. 19 (HealthDay News) -- Genetic biomarkers that are highly accurate in determining physiological age have been identified by researchers at California's Buck Institute for Age Research, who said it may be possible to use these biomarkers to test anti-aging drugs.

The study, which included nematode worms, microarrays that measure changes in gene expression, and complex computer algorithms, was published in the Nov. 20 online edition of Aging Cell.

Chronological age (time from birth) and physiological age (level of function) are rarely in sync, the researchers noted. It's easy to determine chronological age simply by counting forward from birth. But physiological age is more subjective. For example, some 70-year-old people function at the level of someone in their 50s, while other 70-year-olds seem prematurely aged. The same is true of the nematode worms used in the study.

The Buck Institute team conducted individual whole-genome profiles of 104 worms and correlated the results with age-related behavior and survival. The researchers identified a suite of genes actively involved in the aging process.

"This is the first evidence that physiological age can be predicted non-subjectively. This is a first step; our results were not perfect, but we were able to predict the ages of the animals 70 percent of the time, which is far better than anything that has been done before," study author Simon Melov said in a Buck Institute news release.

In humans, being able to examine aging-related biomarkers could help determine if a person is aging faster or slower than would normally be expected. In addition, examining such biomarkers over time would provide a scientific baseline for clinical trials of anti-aging drugs.

"I am optimistic that we will be able to pursue this line of research further," M
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Researchers: Ban on fast food TV advertising would reverse childhood obesity trends
2. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
3. Leeds researchers reshape the future of drug discovery
4. UNC researchers find clue to stopping breast-cancer metastasis
5. U of U researchers to use patients own stem cells to treat heart failure
6. Researchers identify toehold for HIVs assault on brain
7. Researchers Tackle CLL, Diabetes and Trauma-Hemorrhage
8. Researchers Use New Method to Control Bleeding in Hemophilia
9. Stem cells with potential to regenerate injured liver tissue identified by Penn researchers
10. Protein can nurture or devastate brain cells, depending on its friends, researchers find
11. Researchers find stem cells from monkey teeth can stimulate growth and generation of brain cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers ID Suite of Genes in Aging Process
(Date:1/22/2015)... Illinois (PRWEB) January 22, 2015 Deer Path ... will host a Valentine’s Day Happy Hour from 3 p.m. to ... at 12500 Regency Parkway in Huntley, Illinois, serves adults with physical ... Hour event will include Valentine's Day treats, games and sweetheart-themed karaoke. ...
(Date:1/22/2015)... California (PRWEB) January 22, 2015 The City of ... at 10 a.m., to commemorate the 42nd anniversary of the Supreme ... States. , “It’s been 42 years since the Roe vs. Wade ... is still as present as ever,” said City of West Hollywood ...
(Date:1/22/2015)... (PRWEB) January 23, 2015 VogueQueen is a ... affordable prices and many designers are thrilled to have it ... business announces its new collection of prom dresses for the ... to drive the strategic vision and he focuses on continuing ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, has recently released ... website of AngelWeddingDress.com to find more details. , ... for a bridal party. AngelWeddingDress offers a variety of ... maternity wedding dresses are specially designed for 2015. , ...
(Date:1/22/2015)... New York, New York (PRWEB) January 22, 2015 ... filed after Fresenius Medical Care recalled its GranuFlo ... the federal multidistrict litigation underway in U.S. District Court, ... an Order dated January 20th, the Court has remanded ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4
... therapy has always excited scientists, even after twenty years ... tame the evil ways of viruses, such as those ... have realized there is one stumbling block to this ... of an effective transport system, equipped to deliver therapeutic ...
... we shed tears. But exactly what our tears are made of ... sheds some light on the complex design of tears. What we ... up of three distinct, microscopic layers. The middle, watery layer – ... is sandwiched between a layer of mucus and an outer layer ...
... from a more advanced screening process allowing for a ... the plenary session today at the Multidisciplinary Head and ... the American Society for Therapeutic Radiology and Oncology, the ... and Neck Society. ,"By combining conventional techniques ...
... granted a whopping $8.1 million to develop a tool kit ... virus. This was announced by the National Institute of Allergy ... the Avian influenza or the H5N1 virus has the potential ... from the terrorists all over that there could be a ...
... finds that, winning a Nobel Prize adds almost two years ... the cash that accompanies the award.// ,Professor Andrew ... Rablen conducted a study on the effect of status on ... it becomes difficult to say which has more influence on ...
... giant, is finalizing its plan of action, to test its ... bid to establish the most effective vaccine against cervical cancer. ... United States, will seek to evaluate the immune responses of ... of the human papillomavirus. This virus is known to be ...
Cached Medicine News:Health News:Researchers Explore the Effect of Engineered Immune Cells on HIV 2Health News:Researchers Explore the Effect of Engineered Immune Cells on HIV 3Health News:Tears Reveal Some of Their Deepest Secrets to Researchers 2Health News:Tears Reveal Some of Their Deepest Secrets to Researchers 3Health News:New Screening Process Helps Better Diagnose Oral Cancers 2
(Date:1/23/2015)... , Jan. 23, 2015  A new analysis of ... D 2015 enrollment data shows that 81 percent of ... access and extra discounts at certain pharmacies. The findings ... "Preferred pharmacy plans are now the foundation of Medicare ...
(Date:1/23/2015)... , Jan. 23, 2015  Immune Therapeutics, Inc. today announced the ... the compounding, packaging and distributing of its naltrexone tablets.  The ... United States . KRS Global is ... tablets in various strengths for individual patients in response to ...
(Date:1/23/2015)... Idaho , Jan. 23, 2015  Now available for ... No. 7,849,611) support that prevents ankle sprains by cushioning ... brace, it fits securely around the outside of any ... mobility & comfort while still offering protection against sprains. ...
Breaking Medicine Technology:New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2
... Heygood, Orr & Pearson are announcing a Los Angeles Superior ... (NYSE: WPI ) and its subsidiary companies to ... lawsuit over the death of a 37-year-old woman who died while ... represents the parents of Nicole Bristol, who died on Feb. ...
... DIEGO, March 21, 2011 Marshall Edwards, Inc.(Nasdaq: ... clinical development of novel therapeutics targeting cancer metabolism, announced ... clinical trial of intravenous Phenoxodiol in combination with cisplatin ... now available on the International Journal of Gynecological ...
Cached Medicine Technology:Heygood, Orr & Pearson: Los Angeles Court Orders Watson Pharmaceuticals to Produce Documents, Provide Depositions in Fentanyl Patch Death Lawsuit 2Marshall Edwards Announces Publication of Phase II Clinical Trial Results Highlighting Activity of Intravenous Phenoxodiol 2Marshall Edwards Announces Publication of Phase II Clinical Trial Results Highlighting Activity of Intravenous Phenoxodiol 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: