Navigation Links
Researchers ID Genetic Markers for Esophageal Cancer
Date:11/5/2008

Having 4 or more of these 11 genotypes triples risk of disease, study funds

WEDNESDAY, Nov. 5 (HealthDay News) -- Eleven genetic variations believed to be predictors of esophageal cancer have been identified by U.S. researchers.

The University of Texas M. D. Anderson Cancer Center team pinpointed 11 single-nucleotide polymorphisms (SNPs) in microRNA-related genes that showed an association with esophageal cancer.

Each of these unfavorable genotypes was linked with an increased risk of cancer. People with more than four of the 11 genotypes had a more than threefold increased risk of esophageal cancer, according to the study, published in the November issue of Cancer Prevention Research.

"Our ultimate goal is to construct a quantitative cancer risk prediction model based on an individual's epidemiological profile, environment exposure and genetic makeup. This risk prediction model can evaluate each person's relative risk and absolute risk of developing esophageal cancer within a certain time period," study author Dr. Xifeng Wu, a professor in the department of epidemiology, said in an American Association for Cancer Research news release.

Esophageal cancer is the fastest growing cancer in the United States, and the majority of patients are diagnosed at an advanced stage. Being able to identify people at high risk for the disease may improve screening, monitoring and prevention.

"Considering the dramatic increase in incidence, difficulty of early diagnosis, the poor survival rate for esophageal cancer, and the limited knowledge of the natural history of the tumor, we need a greater understanding of the etiology of esophageal cancer for improvement of diagnosis and hopefully a better prognosis," Wu said.

Along with genetics, other risk factors for esophageal cancer include obesity, smoking and gastrointestinal reflux disease.

More information

The U.S. National Cancer Institute has more about esophageal cancer.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, Nov. 5, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Researchers identify mechanism, possible drug treatment for tumors in neurofibromatosis
2. Cancer requires support from immune system to develop, UT Southwestern researchers report
3. Researchers find new chemical key that could unlock hundreds of new antibiotics
4. Penn researchers find key to Sonic hedgehog control of brain development
5. Temple researchers look for behavioral link between breastfeeding and lower risk of obesity
6. MU researchers advance health communication for at-risk populations
7. Researchers Find More Genes Linked to Lung Cancer
8. Researchers estimate lives lost due to delay in antiretroviral drug use for HIV/AIDS in South Africa
9. Georgetown University Med Center reproductive health researchers tackle public health concerns
10. Stem-cell sentry sounds the alarm to maintain balance between cancer and aging, U-M researchers find
11. Steroids aid recovery from pneumonia, UT Southwestern researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers ID Genetic Markers for Esophageal Cancer
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... International Protein, ... nutritional and bodybuilding supplements, announced it attended the January ECRM trade show in Hilton ... and nutritional scientist who was determined to create a line of products that would ...
(Date:1/20/2017)... ... , ... “Mary Magdalene: Grace is Greater than Sin”: a unique and ... Christ firsthand. “Mary Magdalene: Grace is Greater than Sin” is the creation of published ... with countless women who had little knowledge of the female characters portrayed in the ...
(Date:1/20/2017)... Farmville, NC (PRWEB) , ... January 20, 2017 ... ... the vPEP ® Oscillating Positive Expiratory Pressure (OPEP) device, was featured in ... article by Doug Pursley, MEd, RRT-ACCS, FAARC, “Analysis of Three Oscillating Positive ...
(Date:1/20/2017)... ... 20, 2017 , ... “The Land of More and More”: a brilliant ... hunger, and shares the simple and achievable answer. “The Land of More and More” ... Fairview Missionary Church in Angola, Indiana where he works with the children’s ministry department. ...
(Date:1/19/2017)... ... 19, 2017 , ... Next week after January 20th, the fear for many ... that circumvent health needs of over 30 million. Many interviews with Dr. Carol Francis ... government public servants were suppose to prioritize. Interviews provided below. , Among ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... YORK , Jan. 19, 2017 This ... the current and future scenario of the global market. ... rising opioid consumption. Severe chronic constipation is a major ... to traditional laxatives. Hence, novel targeted therapy has been ... OIC sufferers, launch of targeted medicines, and growing awareness ...
(Date:1/19/2017)... 19, 2017  Stealth BioTherapeutics Inc. ( Stealth ), ... dysfunction, today announced new additions to its senior leadership ... Medical Officer, and Daniel Geffken as interim ... Jim Carr , Pharm.D. has been promoted to Chief ... to welcome Doug and Daniel to our management team, ...
(Date:1/19/2017)... January 19, 2017 According to a study ... is set to witness a CAGR of 6.5% during the forecast ... will continue to be the leading market for cryotherapy globally ... ... emphasizing on ensuring affordable and adequate supply of gas in order ...
Breaking Medicine Technology: