Navigation Links
Researchers ID Genetic Markers for Esophageal Cancer
Date:11/5/2008

Having 4 or more of these 11 genotypes triples risk of disease, study funds

WEDNESDAY, Nov. 5 (HealthDay News) -- Eleven genetic variations believed to be predictors of esophageal cancer have been identified by U.S. researchers.

The University of Texas M. D. Anderson Cancer Center team pinpointed 11 single-nucleotide polymorphisms (SNPs) in microRNA-related genes that showed an association with esophageal cancer.

Each of these unfavorable genotypes was linked with an increased risk of cancer. People with more than four of the 11 genotypes had a more than threefold increased risk of esophageal cancer, according to the study, published in the November issue of Cancer Prevention Research.

"Our ultimate goal is to construct a quantitative cancer risk prediction model based on an individual's epidemiological profile, environment exposure and genetic makeup. This risk prediction model can evaluate each person's relative risk and absolute risk of developing esophageal cancer within a certain time period," study author Dr. Xifeng Wu, a professor in the department of epidemiology, said in an American Association for Cancer Research news release.

Esophageal cancer is the fastest growing cancer in the United States, and the majority of patients are diagnosed at an advanced stage. Being able to identify people at high risk for the disease may improve screening, monitoring and prevention.

"Considering the dramatic increase in incidence, difficulty of early diagnosis, the poor survival rate for esophageal cancer, and the limited knowledge of the natural history of the tumor, we need a greater understanding of the etiology of esophageal cancer for improvement of diagnosis and hopefully a better prognosis," Wu said.

Along with genetics, other risk factors for esophageal cancer include obesity, smoking and gastrointestinal reflux disease.

More information

The U.S. National Cancer Institute has more about esophageal cancer.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, Nov. 5, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Researchers identify mechanism, possible drug treatment for tumors in neurofibromatosis
2. Cancer requires support from immune system to develop, UT Southwestern researchers report
3. Researchers find new chemical key that could unlock hundreds of new antibiotics
4. Penn researchers find key to Sonic hedgehog control of brain development
5. Temple researchers look for behavioral link between breastfeeding and lower risk of obesity
6. MU researchers advance health communication for at-risk populations
7. Researchers Find More Genes Linked to Lung Cancer
8. Researchers estimate lives lost due to delay in antiretroviral drug use for HIV/AIDS in South Africa
9. Georgetown University Med Center reproductive health researchers tackle public health concerns
10. Stem-cell sentry sounds the alarm to maintain balance between cancer and aging, U-M researchers find
11. Steroids aid recovery from pneumonia, UT Southwestern researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers ID Genetic Markers for Esophageal Cancer
(Date:3/24/2017)... ... March 24, 2017 , ... As the standards bearer ... communications platform that positions them as the go-to thought leader in all matters ... publication as an always-on, always-fresh news, views and advocacy engine, called ONS Voice. ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... ) announced their partnership to prep patients for colonoscopy at the HyGIeaCare® Center ... in 87th Ave., Miami, FL. , The HyGIeaCare® Prep, cleared by ...
(Date:3/24/2017)... ... ... “Vintage and Harvest A Cultivation of Christian Love” is the creation of ... Carolina with his wife, Anna Marie. He and his wife are the proud parents ... the author of “Shadow and Substance.” , “Love, the agape kind, is seen as ...
(Date:3/23/2017)... ... ... The physicians of KSF Orthopaedic Center PA are proud to announce the ... located at 2255 E. Mossy Oaks Rd., Suite 440, Spring, Texas 77389 inside the ... living in the north Houston area (The Woodlands, Conroe, Magnolia, Kingwood, Humble) with an ...
(Date:3/23/2017)... Grimsby, Ontario (PRWEB) , ... March 23, 2017 , ... The MBI “Hall of Fame” ... or whose acts have had a significant impact on the careers of all others involved. ... with NRB Inc. was inducted into the MBI’s Hall of Fame. The induction took ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , Mar 24, 2017 The Board ... the company,s Annual Report 2016 including the complete 2016 Annual ... and available on Nordic Nanovector,s website in the section Investor ... ... IR enquiries: Tone Kvåle, Chief Financial Officer Cell: +47-91-51-95-76 Email: ...
(Date:3/23/2017)... March 23, 2017  Transportation Insight, a multi-modal lead ... supply chain management firm with expertise serving clients in ... Rick Zaffarano was named a 2017 ... Chain by the only publication exclusively dedicated to covering ... chain. "Rick has brought to Transportation Insight ...
(Date:3/23/2017)... Summary Global ... guide Primary Hyperoxaluria - Pipeline Review, H1 2017, ... Urinary System And Sex Hormones) pipeline landscape. ... recurrent kidney and bladder stones. It results from ... include blood in the urine, pain when urinating, ...
Breaking Medicine Technology: