Navigation Links
Researchers Discover a Gene That Is Associated with Obesity
Date:7/19/2013

Washington, USA (PRWEB) July 19, 2013

In an article found on Sciencedaily.com, researchers from the Spanish National Cancer Research Centre (CNIO) discovered the key role of the gene RAP1, a gene that protects telomeres – the ends of chromosomes – and it’s link to obesity.

"We still don't know what evolutionary significance to attach to it, but it is at the very least interesting that a telomere gene is related to obesity," says Maria Blasco, CNIO director and co-author of the study published today in the journal Cell Reports.

RAP1 forms part of what’s called the shelterin complex, which is a group of proteins that makes up the protective hood of telomeres. Telomeres are found at the end of the chromosomes that shortens with each celluar division and thus, measures the ageing of the organism. Studies show that RAP1 is not essential for the survival of the organism, but that won’t mean it doesn’t have its importance in the body. When comparing the genomes of different species, it was shown that RAP1 is the most conserved shelterin of all. RAP1 has not changed at all, despite the long history of evolutionary change. But what is the role in the organism?

The researchers at CNIO found that RAP1 is also present in the rest of the chromosome, not just at in telomeres. They felt that it acts as a regulation for the action of the other genes. CNIO researchers created a lineage of mice without RAP1, and found that they had a model for obesity. In other words, mice lacking RAP1 will gain more weight than those with the RAP1 gene.

"Mice -- especially female mice -- without RAP1 do not eat more, but do gain weight. They suffer from metabolic syndrome, accumulate abdominal fat and present high glucose and cholesterol levels, amongst other symptoms," says Paula Mart&
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related medicine news :

1. Researchers report a complete description of gene expression in the human retina
2. Researchers Find That Setting Weight Loss Ranges Are More Beneficial than Specifics, Making Weight Loss Via Supplements Like Prescopodene More Likely
3. Single dose of ADHD drug can reduce fall risk in older adults -- Ben-Gurion U researchers
4. UCLA researchers find link between intestinal bacteria and white blood cell cancer
5. Cancer researchers discover how BRCA1 mutation starts breast, ovarian cancers
6. Notre Dame researchers offer new insights on cancer cell signaling
7. Use redistricting maps to make organ allocation more equitable, Johns Hopkins researchers advocate
8. Sanford-Burnham researchers develop novel nanoparticle to deliver powerful RNA interference drugs
9. Researchers investigate mechanism of Alzheimers therapy
10. Researchers pinpoint sources of fibrosis-promoting cells that ravage organs
11. Researchers use immunocytochemistry to determine ALK status
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... December 26, 2014 This is a ... the global Sterilizers industry with a focus on the ... market status of the Sterilizers manufacturers and is a ... individuals interested in the industry. This report provides a ... and manufacturing technology. In this part, the report presents ...
(Date:12/25/2014)... 26, 2014 “Every three months the trends ... A-line sweetheart evening dress will be one of the hottest ... of Yunx.co.uk says. Today, the company releases 26 A-line sweetheart ... to 80% off. , “We are trying our best ... with our latest designs. Along with affordable prices, we provide ...
(Date:12/25/2014)... 25, 2014 BambooFlooringChina.com sells many bamboo ... bamboo flooring. Today, the company announces big discounts ... styles and colors. , BambooFlooringChina.com is the world’s leader ... promotion is valid until Jan. 20, 2015. , The ... woven with a natural thread. All the bamboo strips ...
(Date:12/25/2014)... 25, 2014 (HealthDay News) -- The risk of burns ... so you need to be extra cautious, an expert ... see a significant increase in patients coming in with ... Suffolk County Volunteer Firefighters Burn Center of Stony Brook ... be full of joy, but if not careful, could ...
(Date:12/25/2014)... New York, New York (PRWEB) December 25, 2014 ... ) continue to move forward in a number ... Southern District of West Virginia, Bernstein Liebhard LLP reports. ... the Court is scheduled to convene a Joint Status ... 2015, at 10:00 a.m. Parties have been directed to ...
Breaking Medicine News(10 mins):Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2Health News:Don't Let Burns Mar Your Holidays 2Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 3Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 4
... Genome Project (HGP) have identified chromosomes which are believed ... 23 pairs of human chromosomes, 3 are believed to ... the research at the Wellcome Trust's Sanger Centre, near ... treating all kinds of major ailments// ranging from asthma ...
... can be hard on the body. Stress affects the metabolism ... to reduce impact of stress, and it's probably good advice ... rep, found that appointments and deadlines can be stressful. She ... small, but they do tend to affect your blood sugar. ...
... lesions known as Kaposi's sarcoma are densely related to ... among US gay men before the HIV epidemic ever ... HIV when more men were implementing safe anal sex ... virus remained common.// They think that transmission routes other ...
... future, small handheld echocardiography machines will be used ... The smaller machines can detect heart abnormalities needing ... just minimal training, says Dr. John Alexander, based ... Duke University.// ,For years, cardiologists have recommended ...
... telesurgical operation has been carried out. ,Doctors in the ... in eastern France by remotely operating a surgical robot ... surgeon to perform an operation on a patient anywhere ... Telesurgery in Strasbourg say the procedure was successful and ...
... can actually repair itself by growing new cells after a heart ... and Italy. Dr. Piero Anversa and colleagues of the New York ... myocytes continued to divide after a heart attack.// , ... 13 people who died within a few days of having a ...
Cached Medicine News:Health News:Oral Sex may carry AIDS related Cancer Virus 2Health News:Handheld ECG: stethoscope of the future 2
(Date:12/24/2014)... 24, 2014  The International Trade Commission (ITC) issued its ... BMC Medical. In a notice issued on December 23, the ... patent on its humidifier was invalid. BMC President, ... "We are very excited with the ITC,s decision in this ... have taken since the very beginning on the key patents ...
(Date:12/24/2014)... and FARMINGTON, Conn. ... Inc. (NYSE MKT: PTN), a biopharmaceutical company developing ... diseases with significant unmet medical need and commercial ... a private placement of 2,050,000 shares of its ... 24,949,325 shares of its common stock.  Funds under ...
(Date:12/24/2014)... 2014 Echo Therapeutics, Inc. (NASDAQ: ... on skin permeation, continuous glucose monitoring and associated ... has been appointed Chief Executive Officer effective ... 20 years of experience in the medical device, ... served as Vice President, Business Development, Otsuka Pharmaceuticals as ...
Breaking Medicine Technology:ITC Final Decision Goes Against ResMed (RMD) Monumental Win for 3B/BMC 2Palatin Completes $20 Million Equity and $10 Million Debt Financings 2Palatin Completes $20 Million Equity and $10 Million Debt Financings 3Palatin Completes $20 Million Equity and $10 Million Debt Financings 4Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 2Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: