Navigation Links
Researchers Develop Quick Way to Create Human Antibodies
Date:4/30/2008

Finding could speed development of vaccines for new flu strains, other health threats

WEDNESDAY, April 30 (HealthDay News) -- Researchers have devised a rapid and efficient method for generating protein sentinels of the immune system, called monoclonal antibodies, which mark and neutralize foreign invaders.

The development could potentially accelerate the traditionally challenging task of generating human antibodies, which can be used both to develop faster disease diagnostics -- for instance, to test for a new flu strain shortly after it emerges -- as well as safer and more effective medications, including vaccines.

"I think it's an important, incremental advance in our ability to provide antigen-specific monoclonal antibodies quickly and efficiently," said Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases. He was not involved with the study, but the institute did fund some of the research.

The findings were published online April 30 in the journal Nature.

When a person is exposed to a germ or a vaccine, the immune system mounts a series of challenges to confront the foreign particles. One of those responses involves so-called B cells, which begin to secrete antibodies. Antibodies are proteins, and each binds to a specific three-dimensional shape, or antigen, on the pathogen's surface, blocking its ability to enter cells, or marking it for destruction by other immune cells.

Each B cell can make only one type of antibody. But because most antigens are relatively large, there may be several different B cells whose antibodies will bind to any given antigen. The resulting pool of antibodies is termed "polyclonal," because it arises from multiple clones of activated B cells.

A monoclonal antibody, as its name implies, is the product of a single B-cell clone, so it binds just to a single shape on the antigen's surface. Monoclonals are
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... Recently, the famous review website, Top10BestSEOHosting.com, has ... . According to the site, GoDaddy, Bluehost and ... the world. “Nowadays, Joomla hosting is a very ... hosting. The account owner is allowed to use ... under a specific name, brand or company,” the ...
(Date:10/25/2014)... York (PRWEB) October 25, 2014 The ... ) will be addressed in December, when the U.S. ... hearing session. According to a Hearing Session Order issued ... the matter will be heard on December 4, 2014, ... at 9:30 a.m. (In Re: Xarelto Products Liability Litigation, ...
(Date:10/25/2014)... TASC (Total Administrative Services Corporation), ... account management services, announces the release of four ... taxes, reduce administrative workload, and lessen liability. ... the efficient handling of complex, time-sensitive, and labor-consuming ... meets their goals and objectives. The four Suites ...
(Date:10/25/2014)... October 25, 2014 The federal ... http://www.vaginalmeshlawsuit2015.com/ ) filed against Boston Scientific Corp. ... District Court, Southern District of West Virginia has ... Punitive Damages in a group of cases filed ... issued on October 21st, U.S. District Judge Joseph ...
(Date:10/25/2014)... -- Not getting the right amount of sleep might ... suggests. Those who sleep less or more than ... be more prone to developing the chronic condition, which ... authors concluded that duration and quality of sleep are ... bowel diseases. "Both short and long durations of ...
Breaking Medicine News(10 mins):Health News:Top10BestSEOHosting.com: GoDaddy, Bluehost And Hostgator Are Among The Most Excellent Suppliers In The World 2Health News:Xarelto Lawsuit News: JPML to Hear Oral Arguments on Proposed Xarelto Multidistrict Litigation at December Hearing, Bernstein Liebhard LLP Reports 2Health News:Xarelto Lawsuit News: JPML to Hear Oral Arguments on Proposed Xarelto Multidistrict Litigation at December Hearing, Bernstein Liebhard LLP Reports 3Health News:TASC’s New Suites Offer Tax Savings and Protection 2Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 2Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 3Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 4Health News:Sleep Duration Linked to Ulcerative Colitis Risk in Study 2
... Inviting, Child-Friendly Online Information Source for ... ... http://www.searchhope.org , LOS ANGELES, March ... created an innovative, inviting,child-friendly web-based portal that allows sick children and ...
... damage that can occur in babies with congenital heart disease is ... defect results in too much blood in the lungs, more blood ... blood vessel growth is abruptly halted. , You get this burst ... we think the system gets shut down and the lungs dont ...
... NC Researchers at Duke University Medical Center say ... more harm to cardiovascular health in women than in ... Brain, Behavior and Immunity, found that poor sleep is ... biomarkers associated with elevated risk of heart disease and ...
... The Children,s,Hospital of Philadelphia is pleased to name ... Nursing Officer. The appointment follows an,extensive national search., ... coming to Children,s Hospital, Esposito-Herr served as the ... of Maryland Medical,Center, where she also held a ...
... Inc. (Nasdaq: GTIV ), the nation,s leading provider ... scheduled to,present from 8:30 a.m. to 8:55 a.m. ET, ... Global Healthcare Conference in Miami,Florida., The event will ... web cast,which may be accessed by visiting http://investors.gentiva.com/events.cfm ...
... stunted growth , , MONDAY, March 10 (HealthDay News) -- ... patients at risk for bone damage and stunted growth, ... concerns a signal transduction inhibitor (STI) medication known as ... by short-circuiting tumor growth on the molecular level. The ...
Cached Medicine News:Health News:Siegel+Gale Designs New 'HOPE Portal' for Childrens Hospital Los Angeles 2Health News:Siegel+Gale Designs New 'HOPE Portal' for Childrens Hospital Los Angeles 3Health News:Lung damage in babies with congenital heart disease under study 2Health News:Lung damage in babies with congenital heart disease under study 3Health News:Poor sleep more dangerous for women 2Health News:Poor sleep more dangerous for women 3Health News:The Children's Hospital of Philadelphia Appoints New Chief Nursing Officer 2Health News:Gentiva(R) Health Services to Present March 18th at Lehman Brothers Eleventh Annual Global Healthcare Conference in Miami 2Health News:Gentiva(R) Health Services to Present March 18th at Lehman Brothers Eleventh Annual Global Healthcare Conference in Miami 3Health News:New Drug for Brain Cancer Too Dangerous for Pediatric Patients 2Health News:New Drug for Brain Cancer Too Dangerous for Pediatric Patients 3
(Date:10/22/2014)... , Oct. 22, 2014  Paper Pak Industries, ... developed APLS ® Body Guard Bio, a ... spread of bacteria and virus while protecting service ... Guard Bio features a rugged, external nylon shell, ... create a leak-proof inner chamber that contains contaminated ...
(Date:10/22/2014)... , October 22, 2014 A ... Gloves Market (Product type, Form, End user, Application and ... Insights, Analysis, Research, Report, Opportunities, Segmentation and Forecast, 2013 ... gloves market. Based on key trends tracked, it is ... at $7.9 billion by 2020, registering a CAGR of ...
(Date:10/22/2014)... YARDLEY, Pa. , Oct. 22, 2014 /PRNewswire/ ... of their animal health medications, a Global Pharmaceutical ... and Antares serialization technology and turnkey solution to ... Photo - http://photos.prnewswire.com/prnh/20141021/153438 ... The product that was serialized and aggregated by ...
Breaking Medicine Technology:New, State-Of-The-Art Body Bag Minimizes The Spread Of Bacteria And Virus 2Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 2Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 3Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 4Xyntek and Antares Serialization Solution Protects Pets Too! 2
... Registration Trials, HAYWARD, Calif., Sept. 6 Kosan ... has successfully,reached a binding agreement with the U.S. Food ... clinical trial, a pivotal Phase 3 trial,of its Hsp90 ... Through the FDA,s Special Protocol Assessment (SPA),process, Kosan and ...
... Prevalence and Continuous,Abstinence by Dose, Schedule and Antibody Response; Nabi to ... ... Today, BOCA RATON, Fla., Sept. 5 Nabi,Biopharmaceuticals (Nasdaq: ... (Nicotine Conjugate Vaccine), the company,s,innovative and proprietary investigational vaccine being developed ...
Cached Medicine Technology:Kosan Receives Completed Special Protocol Assessment for TIME-1 Pivotal Phase 3 Trial of Tanespimycin in Multiple Myeloma 2Kosan Receives Completed Special Protocol Assessment for TIME-1 Pivotal Phase 3 Trial of Tanespimycin in Multiple Myeloma 3Kosan Receives Completed Special Protocol Assessment for TIME-1 Pivotal Phase 3 Trial of Tanespimycin in Multiple Myeloma 4Kosan Receives Completed Special Protocol Assessment for TIME-1 Pivotal Phase 3 Trial of Tanespimycin in Multiple Myeloma 5Kosan Receives Completed Special Protocol Assessment for TIME-1 Pivotal Phase 3 Trial of Tanespimycin in Multiple Myeloma 6Kosan Receives Completed Special Protocol Assessment for TIME-1 Pivotal Phase 3 Trial of Tanespimycin in Multiple Myeloma 7Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months 2Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months 3Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months 4Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months 5Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months 6Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months 7
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: