Navigation Links
Researchers Create Protective Sac for Growing Stem Cells
Date:3/27/2008

Miniature lab would carry therapeutic cells to their destination in the body

THURSDAY, March 27 (HealthDay News) -- A "mini stem cell lab" created by U.S. researchers holds promise for use in cell therapy and other biological applications, as well as in the design of certain kinds of electronic devices and new materials.

The team at the Institute for BioNanotechnology in Medicine at Northwestern University in Evanston, Ill. uses one polymer and one small molecule that instantly assemble into a flexible but strong sac that creates a "miniature laboratory" in which human stem cells can be grown.

When used in cell therapy, this sac could protect stem cells from the body's immune system until the stem cells reach their destination. The sac would then biodegrade and release the stem cells to do their work, the researchers said.

In tests, they've demonstrated that human stem cells will grow in the sacs, that the sacs can survive for weeks in culture, and that proteins, even large ones, can travel freely across the sac membranes.

The research is described in the March 28 issue of Science.

The Northwestern team also said this method can produce thin films with tailored sizes and shapes, and may have applications in the design of electronic devices by self-assembly (such as solar cells), and the design of new materials.

"We started with two molecules of interest, dissolved in water, and brought the two solutions together," research leader Samuel I. Stupp, a professor of materials science and engineering, chemistry and medicine, said in a prepared statement.

"We expected them to mix, but, much to our surprise, they formed a solid membrane instantly on contact. This was an exciting discovery, and we then proceeded to investigate why it happened. Understanding the surprising molecular mechanism was even more exciting," Stupp said.

One of the molecules is a peptide amphiphile, synthetic molecules developed by Stupp seven years ago that are essential in his work on regenerative medicine. The other molecule is the biopolymer hyaluronic acid, readily found in the human body in places such as joints and cartilage.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



SOURCE: Northwestern University, news release, March 27, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... Maryland (PRWEB) , ... December 09, 2016 , ... ... digital whiteboard display solutions, proudly announced today that a new solution for Emergency ... to fit in the tight space in Emergency Department examination rooms, and with ...
(Date:12/9/2016)... (PRWEB) , ... December 09, 2016 , ... ... program through the Pennsylvania Cable Network (PCN) during the summer of 2016. The ... Implementation Grant provided by the United States Department of Health and Human Services ...
(Date:12/8/2016)... ... 2016 , ... The Florida Hospital Tampa Wound Healing Institute ... (UHMS), the leading authority in hyperbaric medicine. This accreditation identifies the Institute as ... facilities have earned this distinction. This is the second time the Florida Hospital ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... LLC, announced the first national #QuackGivesBack campaign which supported local breast cancer ... our first franchise-wide Quack Gives Back initiative, and we’re very pleased ...
(Date:12/8/2016)... JENNERSVILLE, Pa. (PRWEB) , ... December 08, 2016 ... ... Penn Medicine Southern Chester County, a Property owned by an affiliate of Seavest, ... 72,000 square foot Penn Medicine Southern Chester County ambulatory care center (ACC) was ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... NORWALK, Connecticut , 8 de dezembro de 2016  A Mederi ... a terapia Stretta, um tratamento não cirúrgico para a doença do refluxo gastroesofágico ... Reading ... Live Stretta procedure performed ... Director of Endoscopy at Wuhan Union Hospital ...
(Date:12/8/2016)... , Dec. 8, 2016  Valeant Pharmaceuticals ... TSX: VRX) ("Valeant") today announced positive results from ... study to assess the safety and efficacy of ... treatment of plaque psoriasis. Within ... with moderate to severe psoriasis, IDP-118 showed statistical ...
(Date:12/8/2016)... -- Information products and services provider Elsevier ... , the world,s largest abstract and citation database of peer-reviewed literature, ... from over 5,000 publishers. The new set of metrics will improve ... when to adjust a journal,s editorial strategy. ... , , CiteScore ...
Breaking Medicine Technology: