Navigation Links
Researchers Create Protective Sac for Growing Stem Cells
Date:3/27/2008

Miniature lab would carry therapeutic cells to their destination in the body

THURSDAY, March 27 (HealthDay News) -- A "mini stem cell lab" created by U.S. researchers holds promise for use in cell therapy and other biological applications, as well as in the design of certain kinds of electronic devices and new materials.

The team at the Institute for BioNanotechnology in Medicine at Northwestern University in Evanston, Ill. uses one polymer and one small molecule that instantly assemble into a flexible but strong sac that creates a "miniature laboratory" in which human stem cells can be grown.

When used in cell therapy, this sac could protect stem cells from the body's immune system until the stem cells reach their destination. The sac would then biodegrade and release the stem cells to do their work, the researchers said.

In tests, they've demonstrated that human stem cells will grow in the sacs, that the sacs can survive for weeks in culture, and that proteins, even large ones, can travel freely across the sac membranes.

The research is described in the March 28 issue of Science.

The Northwestern team also said this method can produce thin films with tailored sizes and shapes, and may have applications in the design of electronic devices by self-assembly (such as solar cells), and the design of new materials.

"We started with two molecules of interest, dissolved in water, and brought the two solutions together," research leader Samuel I. Stupp, a professor of materials science and engineering, chemistry and medicine, said in a prepared statement.

"We expected them to mix, but, much to our surprise, they formed a solid membrane instantly on contact. This was an exciting discovery, and we then proceeded to investigate why it happened. Understanding the surprising molecular mechanism was even more exciting," Stupp said.

One of the molecules is a peptide amphiphile, synthetic molecules developed by Stupp seven years ago that are essential in his work on regenerative medicine. The other molecule is the biopolymer hyaluronic acid, readily found in the human body in places such as joints and cartilage.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



SOURCE: Northwestern University, news release, March 27, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ProVest Insurance ... greater Dallas, Miami, and Raleigh regions, is organizing an extended charity drive to ... and deadly chromosome abnormality. , After struggling since birth with several health challenges, ...
(Date:10/13/2017)... IL (PRWEB) , ... October 13, 2017 , ... ... which established the certification process to promote standards of excellence for the field ... Symposium, scheduled for March 22 – 25, 2018 in Orlando, Florida at the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Many families have ... many long-term care insurance companies have a waiver for care if the client has ... period, when the family pays for care, is often waived, so the benefits from ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... viewers the lowdown on sciatica in a new episode of "Success Files," which ... current events and innovation and investigates each subject in-depth with passion and integrity. ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and ... apnea using cutting-edge Oventus O2Vent technology. As many as 18 million Americans ... frequent cessation in breathing. Oral appliances can offer significant relief to about 75 ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)...  South Korean-based healthcare product Development Company I.M. Lab ... Kickstarter. The device will educate the user about ,proper, ... efficiency compared to the dated and pricey CPR training ... of the compression for a more informed CPR training. ... raise $5,000. cprCUBE ...
(Date:10/2/2017)... INDIANAPOLIS , Oct. 2, 2017  Eli Lilly ... its financial results for the third quarter of 2017 ... a conference call on that day with the investment ... performance. The conference call will begin at ... public can access a live webcast of the conference ...
(Date:9/28/2017)... Sept. 28, 2017 Hill-Rom Holdings, Inc. (NYSE: ... conference call and webcast on Friday, November 3, 2017, ... and ending at approximately 8:30 a.m. (CDT) / 9:30 ... company,s 2017 financial performance and guidance for 2018, Hill-Rom ... to enhance operational performance, and long-range financial outlook through ...
Breaking Medicine Technology: