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Researchers: Biomarkers predict effectiveness of radiation treatments for cancer
Date:3/27/2014

ponse to radiation therapy and concurrent chemoradiation, thus allowing for tailored patient-specific treatment strategies."

The study followed two groups of patients. In the first group, researchers screened 18,000 genes and identified five distinct markers. The second group was larger and confirmed these findings and two of them in particular. Two markers were good at predicting whether or not radiation-based therapy would be effective.

Adds Dr. Akervall, "While our findings are encouraging, and a step toward personalized medicine, we hope to do more of this research with a larger, randomized trial."

According to the National Cancer Institute, most cancers of the head and neck usually begin in the squamous cells that line the moist surfaces of the mouth, nose and throat. Three risk factors identified with squamous cell carcinomas of the head and neck include - tobacco and alcohol use, as well as infection with cancer-causing types of human papillomavirus or HPV.


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Contact: Robert Ortlieb
rortlieb@beaumont.edu
248-551-1077
Beaumont Health System
Source:Eurekalert

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