Navigation Links
Researcher wins $2.5 million award from National Institute on Drug Abuse

CINCINNATIA University of Cincinnati (UC) researcher will receive $2.5 million over five years from the National Institute on Drug Abuse (NIDA) to support his work on a potential immunotherapy for cocaine addiction.

Andrew Norman, PhD, a professor in the psychiatry and behavioral neuroscience department, is one of four winners of the NIDA's first Translational Avant-Garde Awards for Innovative Medication Development Research. Award winners receive $500,000 per year for five years to support their research.

Norman, in collaboration with W. James Ball, PhD, of the pharmacology and cell biophysics department, is working on the development of a human monoclonal antibody (an antibody derived from a single cell for use against a specific target) against cocaine. Such an antibody, when injected into the bloodstream, would attach to cocaine, preventing it from entering the brain and thereby limiting its behavioral effects.

This humanized monoclonal antibody has previously been shown by Norman and Ball to reduce cocaine's effects in an animal model of relapse.

"I'm grateful to NIDA for this award, which is vital to our multidisciplinary translational research," says Norman, who is director of the psychiatry and behavioral neuroscience department's neuroscience laboratory and is based at the College of Medicine and at UC's Reading Campus. "It will greatly enhance our development of this potential medication for the treatment of cocaine addiction."

The other three awardees are William Brimijoin, PhD, of the Mayo Clinic; Jia Bei Wang, PhD, of the University of Maryland at Baltimore; and Daniele Piomelli, PhD, of the University of California, Irvine. Brimijoin and Wang are also researching cocaine therapies; Piomelli is pursuing a new medication for smoking cessation.

"Science has clearly shown that drug addiction results from profound disruptions in brain structure and function, presenting numerous potential targets for medications developmentyet, few medications have come to fruition," says NIDA Director Nora Volkow, MD. "The array of problem-solving approaches submitted by the awardees could help us quicken the pace to find urgently needed medications for addiction."

NIDA is a component of the National Institutes of Health, U.S. Department of Health and Human Services. The newly announced awards are an extension of NIDA's Avant-Garde Award for Innovative HIV/AIDS Research, now in its third year.


Contact: Keith Herrell
University of Cincinnati Academic Health Center

Related medicine news :

1. Queens University researchers locate impulse control center in brain
2. Researchers investigate differences in quality of care delivered by US resident and staff physicians
3. UNC researchers identify genetic patterns that may predict osteoarthritis
4. Mayo-led researchers discover genetic variants modifying breast cancer risk
5. Rutgers researchers discover how HIV resists AZT
6. Researchers at SUNY Downstate find drug combination may treat traumatic brain injury
7. Do the math, say UCLA researchers
8. MIT researchers discover an unexpected twist in cancer metabolism
9. OHSU researchers able to determine brain maturity through analyzing MRI scans
10. University of Houston researcher receives National Award of Excellence in Research
11. Lung cancer culprit could offer target for therapy, UT Southwestern researchers report
Post Your Comments:
(Date:11/28/2015)... CA (PRWEB) , ... November 28, 2015 , ... Pixel ... fully customizable media panels to choose from, the possibilities are endless. Users have full ... more. With the ProPanel: Pulse masking effects, users are sure to get heads to ...
(Date:11/27/2015)... Los Angeles, CA (PRWEB) , ... November 27, 2015 , ... ... new study carried out by the University of Toronto and the University of British ... number of hospitalizations for head injuries. The article explains that part of the reason ...
(Date:11/27/2015)... ... 2015 , ... A team of Swiss doctors has released a report on ... just posted the findings on the website. Click here to read the details ... mesothelioma patients who were treated with chemotherapy followed by EPP surgery. Among the 106 ...
(Date:11/27/2015)... ... November 27, 2015 , ... Lizzie’s Lice Pickers just announced a special promotion ... off of their purchase of lice treatment product. In addition, customers will receive a ... company spokesperson. “Finding lice is a sure way to ruin the holidays, so we ...
(Date:11/27/2015)... LOS ANGELES, CA (PRWEB) , ... November 27, 2015 , ... MPWH, the No.1 Herpes-only ... age of 30 (see Table 1-1 ). More than 3.7 billion people under ... simplex virus type 1 (HSV-1), according to WHO's first global estimates of HSV-1 infection ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 2015 ... the  "2016 Future Horizons and Growth ... Testing Market: Supplier Shares, Competitive Intelligence, ... --> ) has ... Future Horizons and Growth Strategies in ...
(Date:11/26/2015)... Research and Markets ( ) has announced the ... Type (Dressings, Therapy Devices, Active Wound Care), Application (Surgical ... Geography - Global Forecast to 2020" report to ... --> The purpose of this report is to ... advanced wound care market. It involves deep dive analysis ...
(Date:11/26/2015)... DUBLIN , November 26, 2015 ... of the "Self Administration of High Viscosity ... ) has announced the addition of ... report to their offering. --> ... the addition of the "Self Administration of ...
Breaking Medicine Technology: