Navigation Links
Researcher wins $2.5 million award from National Institute on Drug Abuse
Date:9/21/2010

CINCINNATIA University of Cincinnati (UC) researcher will receive $2.5 million over five years from the National Institute on Drug Abuse (NIDA) to support his work on a potential immunotherapy for cocaine addiction.

Andrew Norman, PhD, a professor in the psychiatry and behavioral neuroscience department, is one of four winners of the NIDA's first Translational Avant-Garde Awards for Innovative Medication Development Research. Award winners receive $500,000 per year for five years to support their research.

Norman, in collaboration with W. James Ball, PhD, of the pharmacology and cell biophysics department, is working on the development of a human monoclonal antibody (an antibody derived from a single cell for use against a specific target) against cocaine. Such an antibody, when injected into the bloodstream, would attach to cocaine, preventing it from entering the brain and thereby limiting its behavioral effects.

This humanized monoclonal antibody has previously been shown by Norman and Ball to reduce cocaine's effects in an animal model of relapse.

"I'm grateful to NIDA for this award, which is vital to our multidisciplinary translational research," says Norman, who is director of the psychiatry and behavioral neuroscience department's neuroscience laboratory and is based at the College of Medicine and at UC's Reading Campus. "It will greatly enhance our development of this potential medication for the treatment of cocaine addiction."

The other three awardees are William Brimijoin, PhD, of the Mayo Clinic; Jia Bei Wang, PhD, of the University of Maryland at Baltimore; and Daniele Piomelli, PhD, of the University of California, Irvine. Brimijoin and Wang are also researching cocaine therapies; Piomelli is pursuing a new medication for smoking cessation.

"Science has clearly shown that drug addiction results from profound disruptions in brain structure and function, presenting numerous potential targets for medications developmentyet, few medications have come to fruition," says NIDA Director Nora Volkow, MD. "The array of problem-solving approaches submitted by the awardees could help us quicken the pace to find urgently needed medications for addiction."

NIDA is a component of the National Institutes of Health, U.S. Department of Health and Human Services. The newly announced awards are an extension of NIDA's Avant-Garde Award for Innovative HIV/AIDS Research, now in its third year.


'/>"/>

Contact: Keith Herrell
keith.herrell@uc.edu
513-558-4559
University of Cincinnati Academic Health Center
Source:Eurekalert

Related medicine news :

1. Queens University researchers locate impulse control center in brain
2. Researchers investigate differences in quality of care delivered by US resident and staff physicians
3. UNC researchers identify genetic patterns that may predict osteoarthritis
4. Mayo-led researchers discover genetic variants modifying breast cancer risk
5. Rutgers researchers discover how HIV resists AZT
6. Researchers at SUNY Downstate find drug combination may treat traumatic brain injury
7. Do the math, say UCLA researchers
8. MIT researchers discover an unexpected twist in cancer metabolism
9. OHSU researchers able to determine brain maturity through analyzing MRI scans
10. University of Houston researcher receives National Award of Excellence in Research
11. Lung cancer culprit could offer target for therapy, UT Southwestern researchers report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2016)... ... ... Pregnancy Awareness Month offers a great time to get familiar with the latest ... to have a baby, it’s best to get started before age becomes an issue,” ... & Pregnancy Organizer, written for women who plan on becoming pregnant to learn about ...
(Date:5/2/2016)... ... May 02, 2016 , ... Dr. Jonathan Kulbersh of Carolina Facial Plastics isn’t surprised ... five on the list of “ 5 US Cities with the Highest Plastic Rates .” ... and Miami. The results were calculated using a survey by RealSelf and ...
(Date:5/2/2016)... , ... May 02, 2016 , ... The debilitating disease ... and suffering. With no cure, most patients must deal with prescription costs to treat ... card, allowing up to 75% savings at the pharmacy on many common prescriptions. , ...
(Date:5/2/2016)... Ventura, CA (PRWEB) , ... May 02, 2016 ... ... now offering regenerative therapy, which includes amniotic fluid/“stem cells” and Platelet Rich Plasma ... professional athletes and celebrities,” said Dr. James Baranski, D.C., of Advanced Spine & ...
(Date:5/1/2016)... ... 2016 , ... Outdoor Growing Bans Are Sweeping California, which states are next? ... in the hands of the local communities to decide each county’s fate on ... to vote on growing regulations by 3/1/2016 or be forced to follow how the ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... 27, 2016 ... in Zürich gab Strekin AG den Start ... zur Erhaltung des Resthörvermögens von Patienten, denen ... die umfassende Phase-II-Doppelblindstudie mit Placebo-Kontrollgruppe werden momentan ... wird während der Operation direkt ins Mittelohr ...
(Date:4/27/2016)... 27, 2016   ... in Recurring Consumable Sales  Clinical sales grow ... Technologies (Euronext: MKEA, OTCQX: MKEAY) inventor of Cellvizio®, the ... for the first quarter ended March 31, 2016 and ... of its commercial strategy. First Quarter 2016 ...
(Date:4/27/2016)... , April 27, 2016 ... titled, "Skincare Devices Market - Global Industry Analysis, Size, ... to the report, the global skincare devices market was ... anticipated to expand at a CAGR of 10.1% from ... 2023. Browse the full Skincare Devices Market (Treatment ...
Breaking Medicine Technology: