Navigation Links
Researcher wins $2.5 million award from National Institute on Drug Abuse
Date:9/21/2010

CINCINNATIA University of Cincinnati (UC) researcher will receive $2.5 million over five years from the National Institute on Drug Abuse (NIDA) to support his work on a potential immunotherapy for cocaine addiction.

Andrew Norman, PhD, a professor in the psychiatry and behavioral neuroscience department, is one of four winners of the NIDA's first Translational Avant-Garde Awards for Innovative Medication Development Research. Award winners receive $500,000 per year for five years to support their research.

Norman, in collaboration with W. James Ball, PhD, of the pharmacology and cell biophysics department, is working on the development of a human monoclonal antibody (an antibody derived from a single cell for use against a specific target) against cocaine. Such an antibody, when injected into the bloodstream, would attach to cocaine, preventing it from entering the brain and thereby limiting its behavioral effects.

This humanized monoclonal antibody has previously been shown by Norman and Ball to reduce cocaine's effects in an animal model of relapse.

"I'm grateful to NIDA for this award, which is vital to our multidisciplinary translational research," says Norman, who is director of the psychiatry and behavioral neuroscience department's neuroscience laboratory and is based at the College of Medicine and at UC's Reading Campus. "It will greatly enhance our development of this potential medication for the treatment of cocaine addiction."

The other three awardees are William Brimijoin, PhD, of the Mayo Clinic; Jia Bei Wang, PhD, of the University of Maryland at Baltimore; and Daniele Piomelli, PhD, of the University of California, Irvine. Brimijoin and Wang are also researching cocaine therapies; Piomelli is pursuing a new medication for smoking cessation.

"Science has clearly shown that drug addiction results from profound disruptions in brain structure and function, presenting numerous potential targets for medications developmentyet, few medications have come to fruition," says NIDA Director Nora Volkow, MD. "The array of problem-solving approaches submitted by the awardees could help us quicken the pace to find urgently needed medications for addiction."

NIDA is a component of the National Institutes of Health, U.S. Department of Health and Human Services. The newly announced awards are an extension of NIDA's Avant-Garde Award for Innovative HIV/AIDS Research, now in its third year.


'/>"/>

Contact: Keith Herrell
keith.herrell@uc.edu
513-558-4559
University of Cincinnati Academic Health Center
Source:Eurekalert

Related medicine news :

1. Queens University researchers locate impulse control center in brain
2. Researchers investigate differences in quality of care delivered by US resident and staff physicians
3. UNC researchers identify genetic patterns that may predict osteoarthritis
4. Mayo-led researchers discover genetic variants modifying breast cancer risk
5. Rutgers researchers discover how HIV resists AZT
6. Researchers at SUNY Downstate find drug combination may treat traumatic brain injury
7. Do the math, say UCLA researchers
8. MIT researchers discover an unexpected twist in cancer metabolism
9. OHSU researchers able to determine brain maturity through analyzing MRI scans
10. University of Houston researcher receives National Award of Excellence in Research
11. Lung cancer culprit could offer target for therapy, UT Southwestern researchers report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)... ... ... Image One USA veteran franchise owner Maria Bogacki is bringing ... Nashville that will benefit. , “I’ve enjoyed being a part of the Image One ... question that I would bring my business with me,” Bogacki said. “The entire Image ...
(Date:2/11/2016)... ... February 11, 2016 , ... The ... among the top five firms in the “2015/2016 Best in KLAS: Software and ... Staffing. KLAS is a research and insights firm on a global mission to ...
(Date:2/11/2016)... FL (PRWEB) , ... February 11, 2016 , ... ... and advocates will discuss how to improve care by making data on heart ... heart disease. The Summit on Transparency and Public Reporting of Pediatric and Congenital ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... Surgery, Dallas plastic surgeon , Dr. Rod J. Rohrich, and colleagues, examine ... Dr. Rohrich outlines recommendations for rhinoplasty surgeons when addressing this vital area. , ...
(Date:2/11/2016)... ... February 11, 2016 , ... veEDIS Clinical ... technology, with highly adaptable algorithms, has been updated to help Emergency Department physicians ... symptoms consistent with Zikas and a travel history to affected regions, or potential ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... 2016 Potrero Medical, Inc., the developer of the ... appointment of George M. Rapier, III , MD, to ... , WellMed is one of the nation,s largest physician ... members in Texas and ... his own internal medicine practice, he has been instrumental to ...
(Date:2/11/2016)... AAIPharma Services Corp./Cambridge Major Laboratories, Inc. ... development services for the pharmaceutical and biotechnology industries, ... in its Charleston, SC ... recent investments. Charleston ... with small-scale lyophilization. The site has invested in ...
(Date:2/11/2016)... SEOUL, South Korea , Feb. 11, 2016 Wearable posture tracker, ALEX , has ... project fully funded and just seven days left to go, ALEX is said to be delivered to ... http://photos.prnewswire.com/prnh/20160211/332248 ... ... ...
Breaking Medicine Technology: