Navigation Links
Researcher finds elderly lose ability to distinguish between odors
Date:11/10/2011

AURORA, Colo. -- Scientists studying how the sense of smell changes as people age, found that olfactory sensory neurons in those 60 and over showed an unexpected response to odor that made it more difficult to distinguish specific smells, putting them at greater risk from dangerous chemicals and poor nutrition.

"We found clear changes in olfactory sensory neuron responses to odors for those 60 and up," said Professor Diego Restrepo, Ph.D., director of the Center for NeuroScience at the University of Colorado School of Medicine who led the researchers. "When we presented two different odors to the olfactory sensory neurons of younger people they responded to one or the other. The sensory neurons from the elderly responded to both. This would make it harder for the elderly to differentiate between them."

According to the study published in the latest issue of Neurobiology of Aging, those losing their sense of smell are at a higher risk of malnutrition since taste and smell are closely related, they may also be unable to detect spoiled food, leaking gas or toxic vapors.

Researchers looked at 440 subjects in two age groups those 45- years-old and younger and those 60 and over. Their olfactory sensory neurons (OSNs) were tested for their responses to two distinct odors as well as subsets of those odors.

Restrepo wanted to determine if age-related differences in the function of OSNs might contribute to an impairment of the sense of smell. For this, in a collaboration with Monell Chemical Senses Center in Philadelphia, researchers biopsied cells from both age groups.

"Whereas cells from younger donors were highly selective in the odorants to which they responded, cells from older donors were more likely to respond to multiple odor stimuli suggesting a loss of specificity," the study said.

The scientists had expected to find less OSNs in older subjects and they thought the neurons would be less likely to respond to stimuli. In fact, they found as many neurons in the old as the young but those over 60 could not differentiate between two odors, they blended together.

The study suggests that changes in nose and the brain contribute to smell loss in the elderly, Restrepo said.


'/>"/>
Contact: David Kelly
david.kelly@ucdenver.edu
303-315-6374
University of Colorado Denver
Source:Eurekalert

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Tiny fruit fly could offer big clues in fight against obesity, researcher says
6. Researchers create drug to keep tumor growth switched off
7. MSU researcher linking breast cancer patients with alternative therapies
8. UT researcher receives $2.4 million to research obesity, high-risk pregnancy
9. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
10. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
11. Clemson researchers develop hands-free texting application
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, ... and his M.D from the David Geffen School of Medicine at UCLA. He trained ... Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may ... to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To ... for healthy coping following a traumatic event. , Trauma sufferers tend to feel a ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Dr. Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile ... orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Research and Markets has ... 2015-2025: Applications, Technologies, Forecasts" report to their ... Electronics, Smart Skin, Structural Health Monitoring, Composite Smart ... electronics involves electronic and/or electrical components and circuits ... structures such as vehicle bodies or conformally placed ...
(Date:6/24/2016)... 24, 2016 Research and Markets has ... Companion Diagnostic Tests" report to their offering. ... Diagnostics The World Market for Companion Diagnostics ... diagnostics. Market analysis in the report includes the following: ... Vitro Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, a ... invasive and more durable cerebrospinal fluid treatments, today ... The Series-A funding is led by Innova Memphis, ... and other private investors.  Arkis, new financing will ... and the market release of its in-licensed Endexo® ...
Breaking Medicine Technology: