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Researcher, magnet lab receive $2 million grant to target tuberculosis
Date:1/17/2008

Cross thinks the eventual development of a new family of TB drugs could attack the disease in a new and more effective way. He explained that a specific set of proteins appears to be important to TBs ability to attack the body. His team will identify the target proteins that allow bacteria to infect lung tissue. When a drug binds to one of these proteins, it can render the protein ineffective, shutting down its ability to do harm.

We ought to be able to solve the molecular structure of these drug targets, he said. If you know the shape of the protein, then you can design a drug that can bind to it specifically. Getting detailed information about the correct drug target makes it far easier for the pharmaceutical companies to develop safer, more effective treatment.

There has been a lot of interest in our proposal, Cross said, adding, The quality of the graduate students here at FSU made the difference for us. Without a quality research team like this one, this project goes nowhere and our chance of funding work this important would have been zero.


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Contact: Timothy A. Cross
cross@magnet.fsu.edu
850-644-0917
Florida State University
Source:Eurekalert  

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Researcher, magnet lab receive $2 million grant to target tuberculosis
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