Navigation Links
Research uncovers a potential link between Parkinson's and visual problems
Date:2/15/2013

The most common genetic cause of Parkinson's is not only responsible for the condition's distinctive movement problems but may also affect vision, according to new research by scientists at the University of York.

Parkinson's, the second most common form of neurodegenerative disease, principally affects people aged over 60. Its most common symptom is tremor and slowness of movement (bradykinesia) but some people with Parkinson's also experience changes in vision.

Now for the first time, researchers in the University's Department of Biology have established a link between a mutation which triggers Parkinson's and problems with vision in an animal model.

The latest research, part-funded by leading research charity Parkinson's UK is published in Human Molecular Genetics. Scientists at York studied the impact of the most common Parkinson's-related mutation on nerve cells in the visual system of the fruit fly, Drosophila.

Using electroretinagram (ERG) technology they found a gradual loss of function in eye nerve cells with the mutant gene. The fly visual system is a useful laboratory model as it contains similar amounts of dopamine to the human eye.

However, the research team, which was supported by the University's Centre for Chronic Disease and Disorders (C2D2), found that other Parkinson's-related mutations did not affect eye nerve cell function and there was no loss of vision.

Dr Chris Elliott, who led the research, said: "This is a significant step forward as it will help to identify those people with Parkinson's who may be at greater risk of changes in their vision. It will assist clinicians to manage the condition more effectively.

"We have to get away from the idea that Parkinson's is only about movement problems. This work indicates that changes in vision may also affect people with the most common form of inherited Parkinson's."

Claire Bale, Research Communications Manager at Parkinson's UK added: "This new research has uncovered a potentially interesting relationship between one of the most common genes linked to Parkinson's and the development of visual problems.

"But crucially this study looked at fruit flies, so we need to do more research to find out how relevant the findings are to people living with the condition.

"If you have Parkinson's and notice changes in your eyesight, such as blurred or double vision, it's important to discuss this with your specialist or Parkinson's nurse."


'/>"/>

Contact: David Garner
david.garner@york.ac.uk
44-019-043-22153
University of York
Source:Eurekalert

Related medicine news :

1. Researchers uncover new findings on genetic risks of Behçets disease
2. Biocides Market - New Industry Research Report is Now Available for Pre-order at Transparency Market Research
3. Research Foundation for Tick-Borne Infections Fights Lyme Disease, Babesiosis and Encephalitis with Pilot Studies
4. Moffitt researchers find potential new therapeutic target for treating non-small cell lung cancer
5. Researchers discover breakthrough in ovarian cancer
6. The MPN Research Foundation and LLS partner
7. New Research Says Topically Applied L-Carnitine Effective in Treating Oily Skin
8. Benaroya Research Institute announces $4.4 million grant for type 1 diabetes
9. Plasticizers Market - New Industry Research Report is Now Available for Pre Order at Transparency Market Research
10. UNC researchers discover gene that suppresses herpesviruses
11. Researchers discover biological diversity in triple-negative breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/19/2017)... ... ... Braun Industries will be participating as an exhibitor at EMS Today 2017. ... 23-25, 2017 at the Calvin L. Rampton Salt Palace Convention Center in Salt Lake ... on display. , “JEMS is a leader in EMS news and education. ...
(Date:2/19/2017)... ... February 19, 2017 , ... ... in better care, and MEDfx and the Delaware Health Information Network (DHIN) have ... As the nation’s first state-wide health information exchange, DHIN stores and shares real-time ...
(Date:2/18/2017)... ... February 17, 2017 , ... ... Axendia, **FDAnews Free Webinar**, March 1, 2017 — 1:30 p.m. – 2:30 ... regulatory burden? Pay dividends in enhanced and predictable product performance? Streamline processes ...
(Date:2/18/2017)... ... 17, 2017 , ... Butler Mobility invited Ken Matthews to visit its manufacturing ... Ken was impressed with the safety and reliability of the Stannah Stairlift as ... show. This endorsement by Ken Matthews can be heard on News Radio WHP ...
(Date:2/18/2017)... ... February 17, 2017 , ... Park Cities Pet Sitter ... Show on the Pet Life Radio network. The episode, which was posted this ... topics including: what factors led to Park Cities Pet Sitter’s being awarded the 2017 ...
Breaking Medicine News(10 mins):
(Date:2/16/2017)... Research and Markets has announced the addition of ... report to their offering. ... Traditional medical devices include devices (e.g., ... implantables, large endoscopes, needle based drug delivery, lab based diagnostics ... to three decades for the treatment and management of various ...
(Date:2/16/2017)... -- DaVita Inc. (NYSE: DVA ) today announced ... Net income attributable to DaVita Inc. for ... million, or $0.80 per share and $880 million, or $4.29 ... to DaVita Inc. for the quarter and year ended December ... million, or $0.98 per share, and $789 million, or $3.85 ...
(Date:2/16/2017)... 16, 2017  Aralez Pharmaceuticals Inc. (NASDAQ: ... today announced that executive management will participate in the ... February 22-23, 2017. Adrian Adams , Chief Executive ... 1:35 p.m. local time on Wednesday, February 22, 2017. ... the event may be accessed from the Investors section ...
Breaking Medicine Technology: