Navigation Links
Research uncovers a potential link between Parkinson's and visual problems
Date:2/15/2013

The most common genetic cause of Parkinson's is not only responsible for the condition's distinctive movement problems but may also affect vision, according to new research by scientists at the University of York.

Parkinson's, the second most common form of neurodegenerative disease, principally affects people aged over 60. Its most common symptom is tremor and slowness of movement (bradykinesia) but some people with Parkinson's also experience changes in vision.

Now for the first time, researchers in the University's Department of Biology have established a link between a mutation which triggers Parkinson's and problems with vision in an animal model.

The latest research, part-funded by leading research charity Parkinson's UK is published in Human Molecular Genetics. Scientists at York studied the impact of the most common Parkinson's-related mutation on nerve cells in the visual system of the fruit fly, Drosophila.

Using electroretinagram (ERG) technology they found a gradual loss of function in eye nerve cells with the mutant gene. The fly visual system is a useful laboratory model as it contains similar amounts of dopamine to the human eye.

However, the research team, which was supported by the University's Centre for Chronic Disease and Disorders (C2D2), found that other Parkinson's-related mutations did not affect eye nerve cell function and there was no loss of vision.

Dr Chris Elliott, who led the research, said: "This is a significant step forward as it will help to identify those people with Parkinson's who may be at greater risk of changes in their vision. It will assist clinicians to manage the condition more effectively.

"We have to get away from the idea that Parkinson's is only about movement problems. This work indicates that changes in vision may also affect people with the most common form of inherited Parkinson's."

Claire Bale, Research Communications Manager at Parkinson's UK added: "This new research has uncovered a potentially interesting relationship between one of the most common genes linked to Parkinson's and the development of visual problems.

"But crucially this study looked at fruit flies, so we need to do more research to find out how relevant the findings are to people living with the condition.

"If you have Parkinson's and notice changes in your eyesight, such as blurred or double vision, it's important to discuss this with your specialist or Parkinson's nurse."


'/>"/>

Contact: David Garner
david.garner@york.ac.uk
44-019-043-22153
University of York
Source:Eurekalert

Related medicine news :

1. Researchers uncover new findings on genetic risks of Behçets disease
2. Biocides Market - New Industry Research Report is Now Available for Pre-order at Transparency Market Research
3. Research Foundation for Tick-Borne Infections Fights Lyme Disease, Babesiosis and Encephalitis with Pilot Studies
4. Moffitt researchers find potential new therapeutic target for treating non-small cell lung cancer
5. Researchers discover breakthrough in ovarian cancer
6. The MPN Research Foundation and LLS partner
7. New Research Says Topically Applied L-Carnitine Effective in Treating Oily Skin
8. Benaroya Research Institute announces $4.4 million grant for type 1 diabetes
9. Plasticizers Market - New Industry Research Report is Now Available for Pre Order at Transparency Market Research
10. UNC researchers discover gene that suppresses herpesviruses
11. Researchers discover biological diversity in triple-negative breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... Woodland Hills, CA (PRWEB) , ... December 09, ... ... center for young adults, celebrated its 10th anniversary with the grand opening of ... Hills, California. The successful event spanned two days, December 2-3, and was attended ...
(Date:12/9/2016)... ... December 09, 2016 , ... Mediaplanet today announces distribution of the latest ... readers to sign up as an organ donor for the 123,000 people in the ... organ donor can save up to 8 saves through organ donation and enhance many ...
(Date:12/9/2016)... ... December 09, 2016 , ... MEDI+SIGN®, a provider ... that a new solution for Emergency Departments (ED) has been added to their ... Emergency Department examination rooms, and with a simplified pallet of information available to ...
(Date:12/9/2016)... (PRWEB) , ... December 09, 2016 , ... ... program through the Pennsylvania Cable Network (PCN) during the summer of 2016. The ... Implementation Grant provided by the United States Department of Health and Human Services ...
(Date:12/8/2016)... ... December 08, 2016 , ... The Florida Hospital Tampa ... Hyperbaric Medical Society (UHMS), the leading authority in hyperbaric medicine. This accreditation identifies ... few hospitals and facilities have earned this distinction. This is the second time ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... , Dec. 8, 2016  Eli Lilly and Company ... of its phase 3 EXPEDITION3 trial at the 9 ... As previously disclosed, solanezumab did not meet the primary ... solanezumab initiated in people with mild dementia due to ... submissions for solanezumab for the treatment of mild dementia ...
(Date:12/8/2016)... Mederi Therapeutics Inc . anunciou aprovação regulatória, pela CFDA, e lançamento de ... refluxo gastroesofágico (DRGE). Foto -  http://photos.prnewswire.com/prnh/20161207/446903 ... ... procedure performed and broadcast during the Chinese Congress of Digestive Endoscopy, by Professor ... , , ...
(Date:12/8/2016)... , Dec. 8, 2016  Pennsylvania Physician General ... Drug and Alcohol Programs Gary Tennis ... medications, known as benzodiazepines, developed with the help ... are medications that are frequently prescribed for anxiety ... are used with opioid pain medications, benzodiazepines pose ...
Breaking Medicine Technology: